Found 3 Enz. Inhib. hit(s) with Target = 'Lysine-specific demethylase 4E' and Ligand = 'BDBM26119' TargetLysine-specific demethylase 4E(Homo sapiens (Human))
Sapienza University of Rome
Curated by ChEMBL
Sapienza University of Rome
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant JMJD2E (unknown origin) incubated for 15 mins prior to substrate addition by AlphaScreen methodMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 4E(Homo sapiens (Human))
Sapienza University of Rome
Curated by ChEMBL
Sapienza University of Rome
Curated by ChEMBL
In DepthDetails
TargetLysine-specific demethylase 4E(Homo sapiens (Human))
Sapienza University of Rome
Curated by ChEMBL
Sapienza University of Rome
Curated by ChEMBL
Affinity DataIC50: 6.60E+3nMpH: 7.5 T: 2°CAssay Description:A coupled-assay for JMJD2E activity employing formaldehyde dehydrogenase (FDH) from Pseudomonas putida was developed. Formaldehyde release by demethy...More data for this Ligand-Target Pair
