Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 1' and Ligand = 'BDBM50258142'
TargetMetabotropic glutamate receptor 1(RAT)
F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandPNGBDBM50258142(2,7-difluoro-N-(4-(trifluoromethyl)oxazol-2-yl)-9H...)copy SMILEScopy InChI
Affinity DataEC50:  44nMAssay Description:Agonist activity at rat mGlu1 receptor expressed in HEK293 cells assessed as increase in intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3K12PubMed
TargetMetabotropic glutamate receptor 1(RAT)
F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandPNGBDBM50258142(2,7-difluoro-N-(4-(trifluoromethyl)oxazol-2-yl)-9H...)copy SMILEScopy InChI
Affinity DataEC50:  90nMAssay Description:Agonist activity at rat mGlu1 receptor expressed in CHO cells assessed as reversal of glutamate-activated K+ currents by electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3K12PubMed