Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Neuromedin-K receptor' and Ligand = 'BDBM50194556'
TargetNeuromedin-K receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194556(CHEMBL221445 | N'-[3-(4-tert-butyl-piperazin-1-ylm...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Antagonist activity at human NK3 receptor expressed in CHO cells assessed as inhibition of inositol phosphate generationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TD9X0SPubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194556(CHEMBL221445 | N'-[3-(4-tert-butyl-piperazin-1-ylm...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Displacement of [125I]neurokinin B from human cloned NK3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TD9X0SPubMed