Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Neutrophil elastase' and Ligand = 'BDBM211889'
TargetNeutrophil elastase(Homo sapiens (Human))
Boehringer Ingelheim International GmbH

US Patent
LigandPNGBDBM211889(US9290459, 47.4 | US9670166, 47.4)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:Materials: Human neutrophil elastase was purchased from Calbiochem (Cat. No.: 324681) and the elastase substrate MeOSuc-Ala-Ala-Pro-Val-AMC from Bach...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KS6QD5US Patent
TargetNeutrophil elastase(Homo sapiens (Human))
Boehringer Ingelheim International GmbH

US Patent
LigandPNGBDBM211889(US9290459, 47.4 | US9670166, 47.4)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:Materials: Human neutrophil elastase was purchased from Calbiochem (Cat. No.: 324681) and the elastase substrate MeOSuc-Ala-Ala-Pro-Val-AMC from Bach...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25Q4T8FUS Patent
TargetNeutrophil elastase(Homo sapiens (Human))
Boehringer Ingelheim International GmbH

US Patent
LigandPNGBDBM211889(US9290459, 47.4 | US9670166, 47.4)copy SMILEScopy InChI
Affinity DataEC50: <1nMpH: 7.5Assay Description:Various concentrations of the neutrophil elastase inhibitor are incubated with plasma. Subsequently, the enzyme activity is measured using the fluoro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KS6QD5US Patent