Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with Target = 'Prostaglandin E2 receptor EP2 subtype' and Ligand = 'BDBM50092616'
TargetProstaglandin E2 receptor EP2 subtype(Mus musculus (Mouse))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50092616(CHEMBL3586360)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Antagonist activity at mouse EP2 receptor overexpressed in human ECV304 cells assessed as inhibition of prostaglandin E2-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416ZSCPubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50092616(CHEMBL3586360)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Displacement of [3H]-PGE2 from human EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416ZSCPubMed
TargetProstaglandin E2 receptor EP2 subtype(Mus musculus (Mouse))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50092616(CHEMBL3586360)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Displacement of [3H]-PGE2 from mouse EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416ZSCPubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50092616(CHEMBL3586360)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Displacement of [3H]-PGE2 from rat EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416ZSCPubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50092616(CHEMBL3586360)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Antagonist activity at rat EP2 receptor overexpressed in human ECV304 cells assessed as inhibition of prostaglandin E2-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416ZSCPubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50092616(CHEMBL3586360)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Antagonist activity at human EP2 receptor overexpressed in human ECV304 cells assessed as inhibition of prostaglandin E2-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416ZSCPubMed