Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Prostaglandin E2 receptor EP4 subtype' and Ligand = 'BDBM179834'
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
CAYMAN CHEMICAL COMPANY, INC.

US Patent
LigandPNGBDBM179834(US9676712, 2C)copy SMILEScopy InChI
Affinity DataKi:  2.10nM IC50: 5.70nMpH: 6.0Assay Description:200 μl in 96-well plate. Cell membrane homogenates (20 μg protein) are incubated for 120 min at 22° C. with 0.5 nM [3H]PGE2 in the absence ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23X84T9US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
CAYMAN CHEMICAL COMPANY, INC.

US Patent
LigandPNGBDBM179834(US9676712, 2C)copy SMILEScopy InChI
Affinity DataEC50:  0.00100nMAssay Description:1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 μl of reduced serum medium containing 0.5% FBS. Place ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23X84T9US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
CAYMAN CHEMICAL COMPANY, INC.

US Patent
LigandPNGBDBM179834(US9676712, 2C)copy SMILEScopy InChI
Affinity DataEC50:  0.00700nMT: 2°CAssay Description:1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 μL of reduced serum medium containing 0.5% FBE. Place ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23X84T9US Patent