Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Proteasome subunit beta type-10' and Ligand = 'BDBM50426994'
TargetProteasome subunit beta type-10(Homo sapiens (Human))
Leiden Institute of Chemistry and Netherlands Proteomics Centre

Curated by ChEMBL
LigandPNGBDBM50426994(CHEMBL2326533)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of 20S immunoproteasome beta 2 in human Raji cell lysates after 1 hr by competitive ABPP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P63XMPubMed
TargetProteasome subunit beta type-10(Homo sapiens (Human))
Leiden Institute of Chemistry and Netherlands Proteomics Centre

Curated by ChEMBL
LigandPNGBDBM50426994(CHEMBL2326533)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of human 20S immunoproteasome beta-2 using Bz-VGR-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4DRMPubMed
TargetProteasome subunit beta type-10(Homo sapiens (Human))
Leiden Institute of Chemistry and Netherlands Proteomics Centre

Curated by ChEMBL
LigandPNGBDBM50426994(CHEMBL2326533)copy SMILEScopy InChI
Affinity DataIC50: 410nMAssay Description:Inhibition of 20S immunoproteasome beta 2 in human RPMI8226 cell lysates after 1 hr by coomassie brilliant blue staining-based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P63XMPubMed