Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Proteinase-activated receptor 1' and Ligand = 'BDBM50077759'
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50077759(5-[(E)-3-(3-Chloro-phenyl)-acryloylamino]-1H-[1,2,...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of [3H]-S-(p-F-Phe)-Har-L-Har-KY-NH2 binding to Thrombin receptor 1 (PAR-1) on membranes from CHRF cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R78DFPPubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50077759(5-[(E)-3-(3-Chloro-phenyl)-acryloylamino]-1H-[1,2,...)copy SMILEScopy InChI
Affinity DataEC50:  2.40E+3nMAssay Description:Activation of human platelet aggregation (gel-filtered platelets) induced by alpha thrombinMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R78DFPPubMed