Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with Target = 'Purine nucleoside phosphorylase' and Ligand = 'BDBM50039544'
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50039544(2-Amino-7-thiophen-3-ylmethyl-3,5-dihydro-pyrrolo[...)copy SMILEScopy InChI
Affinity DataKi:  3.5nMAssay Description:Inhibitory activity against calf spleen purine nucleoside phosphorylase (PNP) using 2-amino-6-mercapto-7-methyl purine ribonucleoside (MESG) as subst...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5SKNPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50039544(2-Amino-7-thiophen-3-ylmethyl-3,5-dihydro-pyrrolo[...)copy SMILEScopy InChI
Affinity DataKi:  15.6nMAssay Description:Inhibitory activity against calf spleen purine nucleoside phosphorylase (PNP) using inosine as substrate at a concentration of 10 uM.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5SKNPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50039544(2-Amino-7-thiophen-3-ylmethyl-3,5-dihydro-pyrrolo[...)copy SMILEScopy InChI
Affinity DataIC50: 22.6nMAssay Description:Inhibitory activity against calf spleen purine nucleoside phosphorylase (PNP) using inosine as substrate at a concentration of 10 uM.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5SKNPubMed
TargetPurine nucleoside phosphorylase(Rattus norvegicus)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50039544(2-Amino-7-thiophen-3-ylmethyl-3,5-dihydro-pyrrolo[...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Tested for its ability to inhibit calf spleen purine nucleoside phosphorylase (PNP)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21G0K9TPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50039544(2-Amino-7-thiophen-3-ylmethyl-3,5-dihydro-pyrrolo[...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of purine nucleoside phosphorylase against the enzyme from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50039544(2-Amino-7-thiophen-3-ylmethyl-3,5-dihydro-pyrrolo[...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition of purine nucleoside phosphorylase against the enzyme from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed