Found 4 Enz. Inhib. hit(s) with Target = 'Purine nucleoside phosphorylase' and Ligand = 'BDBM50293091' TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research Limited
Curated by ChEMBL
Industrial Research Limited
Curated by ChEMBL
Affinity DataKi: 0.00900nMAssay Description:Inhibition of human PNP by xanthine-oxidase coupled assayMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKd: 55nMAssay Description:Binding affinity to Plasmodium falciparum His6-tagged PNP assessed as reduction in uric acid formation using inosine as substrateMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research Limited
Curated by ChEMBL
Industrial Research Limited
Curated by ChEMBL
Affinity DataKd: 0.00860nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
Affinity DataKd: 55nMT: 2°CAssay Description:The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...More data for this Ligand-Target Pair
