Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Replicase polyprotein 1ab' and Ligand = 'BDBM423411'
TargetReplicase polyprotein 1ab(2019-nCoV)TBA
LigandPNGBDBM423411(US11753373, Compound A-1-h | WO2005113580-Ex-05 | ...)copy SMILEScopy InChI
Affinity DataIC50: 10.2nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z89HJV
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Pfizer Inc.

LigandPNGBDBM423411(US11753373, Compound A-1-h | WO2005113580-Ex-05 | ...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:The SARS 3CLpro FRET assay measures the protease catalyzed cleavage of TAMRA- SITSAVLQSGFRKMK-(DABCYL)-OH to TAMRA - SITSAVLQ and SGFRKMK- (DABCYL)-O...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6NRFPubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Pfizer Inc.

LigandPNGBDBM423411(US11753373, Compound A-1-h | WO2005113580-Ex-05 | ...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Please point to the patents.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0C3WPubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Pfizer Inc.

LigandPNGBDBM423411(US11753373, Compound A-1-h | WO2005113580-Ex-05 | ...)copy SMILEScopy InChI
Affinity DataEC50:  2.00E+4nMAssay Description:Protection from SARS Infection: Neutral Red Endpoint The ability of compounds to protect cells against infection by the SARS coronavirus is measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6NRFPubMed