Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase ULK1' and Ligand = 'BDBM379413'
TargetSerine/threonine-protein kinase ULK1(Homo sapiens (Human))TBA
LigandPNGBDBM379413(N-(cyclopropanecarbonyl)-N-(4-((4-(cyclopropylamin...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant human ULK1 (1-649) expressed in Sf9 cells using myelin basic protein as substrate by ADP-glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3K0JPubMed
TargetSerine/threonine-protein kinase ULK1(Homo sapiens (Human))TBA
LigandPNGBDBM379413(N-(cyclopropanecarbonyl)-N-(4-((4-(cyclopropylamin...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Gamma-32P assays to measure ULK1 kinase activity were performed as previously described. Briefly, Flag ULK1 was transfected into HEK293T cells and 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N30084US Patent
TargetSerine/threonine-protein kinase ULK1(Homo sapiens (Human))TBA
LigandPNGBDBM379413(N-(cyclopropanecarbonyl)-N-(4-((4-(cyclopropylamin...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:ULK1 inhibition assay is a screening assay to identify compounds that inhibit kinase activity of ULK1 using the ULKtide peptide. In some embodiments,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24F1TTDUS Patent
TargetSerine/threonine-protein kinase ULK1(Homo sapiens (Human))TBA
LigandPNGBDBM379413(N-(cyclopropanecarbonyl)-N-(4-((4-(cyclopropylamin...)copy SMILEScopy InChI
Affinity DataIC50: 1.71E+3nMAssay Description:Inhibition of ULK1 (unknown origin) expressed in HEK293T cells incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3K0JPubMed