Found 2 Enz. Inhib. hit(s) with Target = 'Signal transducer and activator of transcription 5B' and Ligand = 'BDBM50514413' TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Univ. Lille
Curated by ChEMBL
Univ. Lille
Curated by ChEMBL
Affinity DataIC50: 2.90E+3nMAssay Description:Binding affinity to MBP-tagged recombinant STAT5b-SH2 domain (unknown origin) using carboxyfluoresceine-labeled phosphotyrosine octapeptide incubated...More data for this Ligand-Target Pair
Affinity DataIC50: 7.60E+4nMAssay Description:Inhibition of STAT5b in mouse BaF3/FLT3-ITD cells assessed as reduction in cell proliferationMore data for this Ligand-Target Pair
