Compile Data Set for Download or QSAR
Found 5 Enz. Inhib. hit(s) with Target = 'Sodium-dependent dopamine transporter' and Ligand = 'BDBM50069813'
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50069813(CHEMBL3407785)copy SMILEScopy InChI
Affinity DataIC50: 229nMAssay Description:Concentration required to inhibit binding of ICAM-1 to LFA-1 (Leukocyte function-associated antigen-1), evaluated ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60RBZPubMed
TargetSodium-dependent dopamine transporter(MOUSE)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50069813(CHEMBL3407785)copy SMILEScopy InChI
Affinity DataIC50: 3.26E+3nMAssay Description:Inhibition of mouse DAT expressed in HEK293 cells assessed as reduction in [3H]-DA uptakeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60RBZPubMed
TargetSodium-dependent dopamine transporter(MOUSE)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50069813(CHEMBL3407785)copy SMILEScopy InChI
Affinity DataEC50:  1.10E+3nMAssay Description:Enhancing of [125I]RTI-55 binding to mouse DAT expressed in HEK293 cells preincubated for 10 mins followed by radioligand addition measured after 90 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60RBZPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50069813(CHEMBL3407785)copy SMILEScopy InChI
Affinity DataEC50:  870nMAssay Description:Enhancing of [3H]mazindol binding to recombinant human DAT expressed in HEK293 cell membranes preincubated for 10 mins followed by radioligand additi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60RBZPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50069813(CHEMBL3407785)copy SMILEScopy InChI
Affinity DataEC50:  9.10nMAssay Description:Enhancing of [125I]RTI-55 binding to recombinant human DAT expressed in HEK293 cell membranes preincubated for 10 mins followed by radioligand additi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60RBZPubMed