Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Thyroid peroxidase' and Ligand = 'BDBM312173'
TargetThyroid peroxidase(Homo sapiens (Human))TBA
LigandPNGBDBM312173(1-{2-[(1S)-1-Aminoethyl]-4-chlorobenzyl}-2-thioxo-...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD44KMPubMed
TargetThyroid peroxidase(Homo sapiens (Human))TBA
LigandPNGBDBM312173(1-{2-[(1S)-1-Aminoethyl]-4-chlorobenzyl}-2-thioxo-...)copy SMILEScopy InChI
Affinity DataIC50: 6.80E+4nMAssay Description:Methods for the determination of MPO inhibitory activity are disclosed in WO 02/090575. The pharmacological activity of compounds disclosed herein wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7MD4US Patent
TargetThyroid peroxidase(Homo sapiens (Human))TBA
LigandPNGBDBM312173(1-{2-[(1S)-1-Aminoethyl]-4-chlorobenzyl}-2-thioxo-...)copy SMILEScopy InChI
Affinity DataIC50: 6.80E+4nMAssay Description:To detect thyroid peroxidase (TPO) inhibitory activity, the production of hypoiodous acid (HOI) was quantified. HOI was detected by reacting it with ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q24296US Patent
TargetThyroid peroxidase(Homo sapiens (Human))TBA
LigandPNGBDBM312173(1-{2-[(1S)-1-Aminoethyl]-4-chlorobenzyl}-2-thioxo-...)copy SMILEScopy InChI
Affinity DataIC50: 6.80E+4nMAssay Description:MPO: The pharmacological activity of compounds disclosed herein was tested in the following screen (Test A) in which the compounds were tested in the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WW7M2NUS Patent