Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Transcription initiation factor TFIID subunit 1 [1504-1635]' and Ligand = 'BDBM346484'
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346484(3-(5-isopropyl-1,3,4-oxadiazol-2-yl)-2,6-dimethyl-...)copy SMILES
Affinity DataIC50: 27.6nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346484(3-(5-isopropyl-1,3,4-oxadiazol-2-yl)-2,6-dimethyl-...)copy SMILES
Affinity DataIC50: 49.5nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1504-1635](Homo sapiens (Human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346484(3-(5-isopropyl-1,3,4-oxadiazol-2-yl)-2,6-dimethyl-...)copy SMILES
Affinity DataIC50: 126nMAssay Description:His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent