Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Fgr' and Ligand = 'BDBM13216'
TargetTyrosine-protein kinase Fgr(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27D2XFPUS Patent
TargetTyrosine-protein kinase Fgr(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)copy SMILEScopy InChI
Affinity DataKd:  0.5nMAssay Description:Binding constant for FGR kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4RX2PubMed
TargetTyrosine-protein kinase Fgr(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)copy SMILEScopy InChI
Affinity DataKd:  0.5nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JD4V4CPCBioAssay
TargetTyrosine-protein kinase Fgr(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)copy SMILEScopy InChI
Affinity DataKd:  0.5nMAssay Description:Binding constant for FGR kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMed