Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A' and Ligand = 'BDBM14756'
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
St. John's University

Curated by ChEMBL
LigandPNGBDBM14756((R)-4-[3-(5-Chloro-pyrimidin-2-yloxy)-pyrrolidin-1...)copy SMILEScopy InChI
Affinity DataKi:  44nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V988ZCPubMed
LigandPNGBDBM14756((R)-4-[3-(5-Chloro-pyrimidin-2-yloxy)-pyrrolidin-1...)copy SMILEScopy InChI
Affinity DataKi:  44nMAssay Description:PDE activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using a scintillation proximity assay (SPA). [3H]-AMP was captured by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930RDXPubMed