Found 6 Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4A' and Ligand = 'BDBM50085135' TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
University of Glasgow
Curated by ChEMBL
University of Glasgow
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of full-length PDE4A4 using cAMP as substrate by two-step radiochemical assayMore data for this Ligand-Target Pair
3D Structure (crystal)TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
University of Glasgow
Curated by ChEMBL
University of Glasgow
Curated by ChEMBL
Affinity DataIC50: 88nMAssay Description:Inhibition of human Phosphodiesterase 4A from peripheral blood mononuclear cellsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
University of Glasgow
Curated by ChEMBL
University of Glasgow
Curated by ChEMBL
Affinity DataIC50: 88nMAssay Description:Inhibitory activity against Phosphodiesterase 4A (PDE4A) from human source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
University of Glasgow
Curated by ChEMBL
University of Glasgow
Curated by ChEMBL
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of recombinant human PDE4A10 catalytic domain (290 to 622 residues) expressed in Escherichia coli BL21-CodonPlus(DE3) cells using [3H]cAMP...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
University of Glasgow
Curated by ChEMBL
University of Glasgow
Curated by ChEMBL
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of recombinant human PDE4A10 catalytic domain (290 to 622 residues) expressed in Escherichia coli BL21-CodonPlus(DE3) cells using [3H]cAMP...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
University of Glasgow
Curated by ChEMBL
University of Glasgow
Curated by ChEMBL
Affinity DataEC50: 20nMAssay Description:Induction of SQSTM1-dependent intracellular redistribution of GFP-tagged PDE4A4 assessed as maximal accretion of enzyme into fociMore data for this Ligand-Target Pair
