Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4D' and Ligand = 'BDBM14369'
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Purdue Pharma LP

LigandPNGBDBM14369(3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1-(4-meth...)copy SMILEScopy InChI
Affinity DataKi:  6.60nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5KF0PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Purdue Pharma LP

LigandPNGBDBM14369(3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1-(4-meth...)copy SMILEScopy InChI
Affinity DataKi:  7.60nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5KF0PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Purdue Pharma LP

LigandPNGBDBM14369(3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1-(4-meth...)copy SMILEScopy InChI
Affinity DataKi:  347nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5KF0PubMed