Compile Data Set for Download or QSAR
Found 171 of ic50 data for polymerid = 2737,2739
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of RSK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4M86PubMed
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Inhibition of RSK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3DWTPubMed
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 0.126nMAssay Description:Inhibition of human RSK1 using KKLNRTLSVA as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W380MTPubMed
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 0.126nMAssay Description:Inhibition of human RSK1 using KKLNRTLSVA as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5KB8PubMed
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM139540(US10189849, staurosporine | US10307427, Staurospor...)copy SMILEScopy InChI
Affinity DataIC50: 0.190nMAssay Description:The compound of Example 39, 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, was subjected to a kinase...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2930RVRUS Patent
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM258601(US9493490, 6-(4-(aminomethyl)-2-chlorophenoxy)-7-i...)copy SMILEScopy InChI
Affinity DataIC50: 0.195nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R2109JUS Patent
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM430037(US10538528, Compound 19)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Akt1 was prepared and assays of inhibitory activity of the compound according to the present invention against Akt1 kinase activity in vitro were con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MK6G95US Patent
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM430036(US10538528, Compound 18)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Akt1 was prepared and assays of inhibitory activity of the compound according to the present invention against Akt1 kinase activity in vitro were con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MK6G95US Patent
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of RSK1 using biotinylated substrate preincubated for 15 mins before substrate addition measured after 30 mins by fluorescence microplate ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NG4R1DPubMed
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM430032(US10538528, Compound 14)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Akt1 was prepared and assays of inhibitory activity of the compound according to the present invention against Akt1 kinase activity in vitro were con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MK6G95US Patent
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM430038(US10538528, Compound 20)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Akt1 was prepared and assays of inhibitory activity of the compound according to the present invention against Akt1 kinase activity in vitro were con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MK6G95US Patent
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM430035(US10538528, Compound 17)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Akt1 was prepared and assays of inhibitory activity of the compound according to the present invention against Akt1 kinase activity in vitro were con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MK6G95US Patent
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM430041(US10538528, Compound 23)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Akt1 was prepared and assays of inhibitory activity of the compound according to the present invention against Akt1 kinase activity in vitro were con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MK6G95US Patent
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM199250(US9221808, 1bo | US9221808, 1bo-HCl | US9221808, 1...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of RSK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571G0RPubMed
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM430056(US10538528, Compound 43)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Akt1 was prepared and assays of inhibitory activity of the compound according to the present invention against Akt1 kinase activity in vitro were con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MK6G95US Patent
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM430050(US10538528, Compound 34)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Akt1 was prepared and assays of inhibitory activity of the compound according to the present invention against Akt1 kinase activity in vitro were con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MK6G95US Patent
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM25004(3-[2-(4-amino-1,2,5-oxadiazol-3-yl)-7-(3-aminoprop...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from radiolabeled AT...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5K3HPubMed
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of RSK1 (unknown origin) by Z-LYTE kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7K5KPubMed
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM430031(US10538528, Compound 13)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Akt1 was prepared and assays of inhibitory activity of the compound according to the present invention against Akt1 kinase activity in vitro were con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MK6G95US Patent
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM430047(US10538528, Compound 32)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Akt1 was prepared and assays of inhibitory activity of the compound according to the present invention against Akt1 kinase activity in vitro were con...More data for this Ligand-Target Pair
Ligand InfoMCE
PC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MK6G95US Patent
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM430044(US10538528, Compound 27)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Akt1 was prepared and assays of inhibitory activity of the compound according to the present invention against Akt1 kinase activity in vitro were con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MK6G95US Patent
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM430040(US10538528, Compound 22)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Akt1 was prepared and assays of inhibitory activity of the compound according to the present invention against Akt1 kinase activity in vitro were con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MK6G95US Patent
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM430034(US10538528, Compound 16)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Akt1 was prepared and assays of inhibitory activity of the compound according to the present invention against Akt1 kinase activity in vitro were con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MK6G95US Patent
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM430042(US10538528, Compound 24)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Akt1 was prepared and assays of inhibitory activity of the compound according to the present invention against Akt1 kinase activity in vitro were con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MK6G95US Patent
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM286091((R)¿N-(1-(4-aminobenzyl)-1H-pyrazol-4-yl)-9-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Radioisotope assays (SignalChem) were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862JK5US Patent
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM286091((R)¿N-(1-(4-aminobenzyl)-1H-pyrazol-4-yl)-9-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Radioisotope assays were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radioactive workin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20R9SGDUS Patent
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM430033(US10538528, Compound 15)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Akt1 was prepared and assays of inhibitory activity of the compound according to the present invention against Akt1 kinase activity in vitro were con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MK6G95US Patent
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM430049(US10538528, Compound 33)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Akt1 was prepared and assays of inhibitory activity of the compound according to the present invention against Akt1 kinase activity in vitro were con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MK6G95US Patent
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM430057(US10538528, Compound 44)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Akt1 was prepared and assays of inhibitory activity of the compound according to the present invention against Akt1 kinase activity in vitro were con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MK6G95US Patent
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM430043(US10538528, Compound 25)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Akt1 was prepared and assays of inhibitory activity of the compound according to the present invention against Akt1 kinase activity in vitro were con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MK6G95US Patent
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM50609121(CHEMBL5276100)
Ligand Info
In DepthDetails
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM25017(2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimeth...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of RSK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4PCPPubMed
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM430051(US10538528, Compound 37)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Akt1 was prepared and assays of inhibitory activity of the compound according to the present invention against Akt1 kinase activity in vitro were con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MK6G95US Patent
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM430029(US10538528, Compound 5)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:Akt1 was prepared and assays of inhibitory activity of the compound according to the present invention against Akt1 kinase activity in vitro were con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MK6G95US Patent
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM430053(US10538528, Compound 40)copy SMILEScopy InChI
Affinity DataIC50: 3.60nMAssay Description:Akt1 was prepared and assays of inhibitory activity of the compound according to the present invention against Akt1 kinase activity in vitro were con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MK6G95US Patent
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM258598(US9493490, Example 10 | US9493490, G)copy SMILEScopy InChI
Affinity DataIC50: 3.62nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R2109JUS Patent
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM430039(US10538528, Compound 21)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Akt1 was prepared and assays of inhibitory activity of the compound according to the present invention against Akt1 kinase activity in vitro were con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MK6G95US Patent
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM50592745(CHEMBL5188373)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J96BC1PubMed
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM430052(US10538528, Compound 39)copy SMILEScopy InChI
Affinity DataIC50: 4.10nMAssay Description:Akt1 was prepared and assays of inhibitory activity of the compound according to the present invention against Akt1 kinase activity in vitro were con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MK6G95US Patent
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM430055(US10538528, Compound 42)copy SMILEScopy InChI
Affinity DataIC50: 4.80nMAssay Description:Akt1 was prepared and assays of inhibitory activity of the compound according to the present invention against Akt1 kinase activity in vitro were con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MK6G95US Patent
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM50111384(CHEMBL3604794)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of full length recombinant His-tagged human RSK1 expressed in baculovirus expression system using biotin-labelled AGAGRSRHSSYPAGT-OH as su...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD44DCPubMed
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM258595(US9493490, 6-(4-(aminomethyl)-2-fluorophenoxy)-7-m...)copy SMILEScopy InChI
Affinity DataIC50: 5.01nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R2109JUS Patent
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM258600(US9493490, 6-(3-(aminomethyl)-2-fluorophenoxy)-7-m...)copy SMILEScopy InChI
Affinity DataIC50: 5.19nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R2109JUS Patent
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM50234990(CHEMBL4062453)copy SMILEScopy InChI
Affinity DataIC50: 5.40nMAssay Description:Inhibition of RSK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5QFNPubMed
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM236890(US9388171, II-64)copy SMILEScopy InChI
Affinity DataIC50: 5.47nMT: 2°CAssay Description:HepG2 cells were obtained from ATCC and grown in DMEM supplemented with 10% fetal bovine serum. Cells were plated in 96-well plates at 35,000 cells/w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC81SVUS Patent
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM430030(US10538528, Compound 11)copy SMILEScopy InChI
Affinity DataIC50: 5.80nMAssay Description:Akt1 was prepared and assays of inhibitory activity of the compound according to the present invention against Akt1 kinase activity in vitro were con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MK6G95US Patent
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM236878(US9388171, I-6)copy SMILEScopy InChI
Affinity DataIC50: 5.96nMT: 2°CAssay Description:HepG2 cells were obtained from ATCC and grown in DMEM supplemented with 10% fetal bovine serum. Cells were plated in 96-well plates at 35,000 cells/w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC81SVUS Patent
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM50111384(CHEMBL3604794)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of RSK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4PCPPubMed
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM50111385(CHEMBL3604793)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of full length recombinant His-tagged human RSK1 expressed in baculovirus expression system using biotin-labelled AGAGRSRHSSYPAGT-OH as su...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD44DCPubMed
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandPNGBDBM25005(4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-7-(3-aminoprop...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from radiolabeled AT...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5K3HPubMed
Displayed 1 to 50 (of 171 total ) | Next | Last >>
Jump to: