Compile Data Set for Download or QSAR
Found 42 of ki data for polymerid = 50000332
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50270877((R)-4-(4-((2-(4-chlorophenyl)-5,5-dimethylcyclohex...)copy SMILEScopy InChI
Affinity DataKi: <0.5nMAssay Description:Binding affinity to BH3 binding groove of BclXLMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58M4HPubMed
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM21447(4-(4-{[2-(4-chlorophenyl)phenyl]methyl}piperazin-1...)copy SMILEScopy InChI
Affinity DataKi:  0.600nMAssay Description:Binding affinity to Bcl-XL assessed as inhibition of Bcl-XL-BAD derived peptide interactionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7VTVPubMed
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50274325((R)-4-(4-((2-(4-Chlorophenyl)-5,5-dimethylcyclohex...)copy SMILEScopy InChI
Affinity DataKi:  1.40nMAssay Description:Displacement of fluorescein labeled BAD peptide from Bcl-XL (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057FR7PubMed
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50274315((R)-4-(4-((4'-Chlorobiphenyl-2-yl)methyl)piperazin...)copy SMILEScopy InChI
Affinity DataKi:  14nMAssay Description:Displacement of fluorescein labeled BAD peptide from Bcl-XL (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057FR7PubMed
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50568338(CHEMBL4872320)copy SMILES
Affinity DataKi:  100nMAssay Description:Binding affinity to Bcl-2 (unknown origin) by fluorescence polarization competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35ZDSPubMed
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50568328(CHEMBL4864929)copy SMILES
Affinity DataKi:  250nMAssay Description:Binding affinity to Bcl-2 (unknown origin) by fluorescence polarization competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35ZDSPubMed
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50568326(CHEMBL4872671)copy SMILES
Affinity DataKi:  250nMAssay Description:Binding affinity to Bcl-2 (unknown origin) by fluorescence polarization competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35ZDSPubMed
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50568330(CHEMBL4855114)copy SMILES
Affinity DataKi:  300nMAssay Description:Binding affinity to Bcl-2 (unknown origin) by fluorescence polarization competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35ZDSPubMed
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50568325(CHEMBL4870608)copy SMILES
Affinity DataKi:  360nMAssay Description:Binding affinity to Bcl-2 (unknown origin) by fluorescence polarization competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35ZDSPubMed
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM23223(7-[8-formyl-1,6,7-trihydroxy-3-methyl-5-(propan-2-...)copy SMILEScopy InChI
Affinity DataKi:  460nMAssay Description:Binding affinity to Bcl-2 (unknown origin) by fluorescence polarization competition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35ZDSPubMed
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50568324(CHEMBL4860820)copy SMILES
Affinity DataKi:  490nMAssay Description:Binding affinity to Bcl-2 (unknown origin) by fluorescence polarization competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35ZDSPubMed
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50568340(CHEMBL4852823)copy SMILES
Affinity DataKi:  530nMAssay Description:Binding affinity to Bcl-2 (unknown origin) by fluorescence polarization competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35ZDSPubMed
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50568322(CHEMBL4864735)copy SMILES
Affinity DataKi:  560nMAssay Description:Binding affinity to Bcl-2 (unknown origin) by fluorescence polarization competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35ZDSPubMed
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50208819(2-{2,3,4-trihydroxy-5-[methyl-(3-phenylpropyl)sulf...)copy SMILEScopy InChI
Affinity DataKi:  638nMAssay Description:Displacement of FAM-Bak BH3 peptide from human Bcl-xL by FP-based binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9HXVPubMed
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50568336(CHEMBL4870458)copy SMILES
Affinity DataKi:  660nMAssay Description:Binding affinity to Bcl-2 (unknown origin) by fluorescence polarization competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35ZDSPubMed
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50568334(CHEMBL4846508)copy SMILES
Affinity DataKi:  800nMAssay Description:Binding affinity to Bcl-2 (unknown origin) by fluorescence polarization competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35ZDSPubMed
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50568341(CHEMBL4870837)copy SMILES
Affinity DataKi:  820nMAssay Description:Binding affinity to Bcl-2 (unknown origin) by fluorescence polarization competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35ZDSPubMed
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50568332(CHEMBL4856143)copy SMILES
Affinity DataKi:  820nMAssay Description:Binding affinity to Bcl-2 (unknown origin) by fluorescence polarization competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35ZDSPubMed
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50568329(CHEMBL4876348)copy SMILES
Affinity DataKi:  870nMAssay Description:Binding affinity to Bcl-2 (unknown origin) by fluorescence polarization competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35ZDSPubMed
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50372177(CHEMBL404899)copy SMILEScopy InChI
Affinity DataKi:  970nMAssay Description:Inhibition of Bak peptide binding to human recombinant Bcl-XlMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1F7SPubMed
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50376902(CHEMBL408194)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of BH3 peptide binding to human recombinant BCL-XL by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1RMWPubMed
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50568339(CHEMBL4876147)copy SMILES
Affinity DataKi:  1.08E+3nMAssay Description:Binding affinity to Bcl-2 (unknown origin) by fluorescence polarization competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35ZDSPubMed
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50371611(CHEMBL258819)copy SMILEScopy InChI
Affinity DataKi:  1.11E+3nMAssay Description:Binding affinity to human Bcl-xL protein by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD4XNXPubMed
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50214871(1,4-bis(5,6,7-trihydroxy-8-isobutyl-2-methyl-4-oxo...)copy SMILEScopy InChI
Affinity DataKi:  1.20E+3nMAssay Description:Displacement of FAM-Bim peptide from human Bcl-XL by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ87BKPubMed
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50568337(CHEMBL4872495)copy SMILES
Affinity DataKi:  1.28E+3nMAssay Description:Binding affinity to Bcl-2 (unknown origin) by fluorescence polarization competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35ZDSPubMed
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50568333(CHEMBL4859740)copy SMILES
Affinity DataKi:  1.30E+3nMAssay Description:Binding affinity to Bcl-2 (unknown origin) by fluorescence polarization competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35ZDSPubMed
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50371612(CHEMBL259034)copy SMILEScopy InChI
Affinity DataKi:  1.32E+3nMAssay Description:Binding affinity to human Bcl-xL protein by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD4XNXPubMed
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50568331(CHEMBL4875429)copy SMILES
Affinity DataKi:  1.74E+3nMAssay Description:Binding affinity to Bcl-2 (unknown origin) by fluorescence polarization competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35ZDSPubMed
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50568335(CHEMBL4865871)copy SMILES
Affinity DataKi:  1.80E+3nMAssay Description:Binding affinity to Bcl-2 (unknown origin) by fluorescence polarization competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35ZDSPubMed
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50372180(CHEMBL270646)copy SMILEScopy InChI
Affinity DataKi:  2.30E+3nMAssay Description:Inhibition of Bak peptide binding to human recombinant Bcl-XlMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1F7SPubMed
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50372178(CHEMBL406312)copy SMILEScopy InChI
Affinity DataKi:  2.40E+3nMAssay Description:Inhibition of Bak peptide binding to human recombinant Bcl-XlMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1F7SPubMed
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50568323(CHEMBL4878113)copy SMILES
Affinity DataKi:  2.55E+3nMAssay Description:Binding affinity to Bcl-2 (unknown origin) by fluorescence polarization competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35ZDSPubMed
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50568327(CHEMBL4868913)copy SMILES
Affinity DataKi:  3.21E+3nMAssay Description:Binding affinity to Bcl-2 (unknown origin) by fluorescence polarization competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35ZDSPubMed
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50568321(CHEMBL4860027)copy SMILES
Affinity DataKi:  4.53E+3nMAssay Description:Binding affinity to Bcl-2 (unknown origin) by fluorescence polarization competition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35ZDSPubMed
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50202277((S)-2-(5-(4-bromobenzylidene)-4-oxo-2-thioxothiazo...)copy SMILEScopy InChI
Affinity DataKi:  5.25E+3nMAssay Description:Inhibition of Bak peptide binding to human recombinant Bcl-XlMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1F7SPubMed
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50372176(CHEMBL272974)copy SMILEScopy InChI
Affinity DataKi:  8.70E+3nMAssay Description:Inhibition of Bak peptide binding to human recombinant Bcl-XlMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1F7SPubMed
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50162774(ABT-199 | US11420968, Example ABT-199 | Venetoclax)copy SMILEScopy InChI
Affinity DataKi:  1.60E+4nMAssay Description:Binding affinity to Bcl-2 (unknown origin) by fluorescence polarization competition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35ZDSPubMed
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50372173(CHEMBL404644)copy SMILEScopy InChI
Affinity DataKi:  5.84E+4nMAssay Description:Inhibition of Bak peptide binding to human recombinant Bcl-XlMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1F7SPubMed
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50372179(CHEMBL402066)copy SMILEScopy InChI
Affinity DataKi:  1.04E+5nMAssay Description:Inhibition of Bak peptide binding to human recombinant Bcl-XlMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1F7SPubMed
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50372174(CHEMBL256858)copy SMILEScopy InChI
Affinity DataKi:  1.12E+5nMAssay Description:Inhibition of Bak peptide binding to human recombinant Bcl-XlMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1F7SPubMed
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50372175(CHEMBL272110)copy SMILEScopy InChI
Affinity DataKi:  1.34E+5nMAssay Description:Inhibition of Bak peptide binding to human recombinant Bcl-XlMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1F7SPubMed
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics Ltd.

Curated by ChEMBL
LigandPNGBDBM50372172(CHEMBL257687)copy SMILEScopy InChI
Affinity DataKi:  1.76E+5nMAssay Description:Inhibition of Bak peptide binding to human recombinant Bcl-XlMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1F7SPubMed