Compile Data Set for Download or QSAR
Found 286 of ic50 data for polymerid = 50006362
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM589235(US11555009, Compound 15 | US11555009, Compound 29)copy SMILES
Affinity DataIC50: 60nMMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM589235(US11555009, Compound 15 | US11555009, Compound 29)copy SMILES
Affinity DataIC50: 60nMMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM589235(US11555009, Compound 15 | US11555009, Compound 29)copy SMILES
Affinity DataIC50: 60nMAssay Description:The present invention provides a novel class of demethylase FTO inhibitors which inhibit FTO protein activity at very low concentration (typically IC...More data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM50599021(CHEMBL5195767)copy SMILES
Affinity DataIC50: 70nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C72GZPubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM624871(US20230322715, Compound TR-FTO-35)copy SMILES
Affinity DataIC50: 70nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM50596052(CHEMBL5196484)copy SMILES
Affinity DataIC50: 87nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8XWGPubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM50599012(CHEMBL5200892 | US20230322715, Compound TR-FTO-11)copy SMILES
Affinity DataIC50: 110nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM50599012(CHEMBL5200892 | US20230322715, Compound TR-FTO-11)copy SMILES
Affinity DataIC50: 110nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C72GZPubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM50599025(CHEMBL5207866 | US20230322715, Compound TR-FTO-40)copy SMILES
Affinity DataIC50: 160nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM50599025(CHEMBL5207866 | US20230322715, Compound TR-FTO-40)copy SMILES
Affinity DataIC50: 160nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C72GZPubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM50594333(CHEMBL5174419)copy SMILES
Affinity DataIC50: 200nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959NJKPubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM624873(US20230322715, Compound TR-FTO-38)copy SMILES
Affinity DataIC50: 270nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM50599023(CHEMBL5194680)copy SMILES
Affinity DataIC50: 270nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C72GZPubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM50606682(CHEMBL5220094)copy SMILES
Affinity DataIC50: 330nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8X83PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM50485565(CHEMBL465179)copy SMILEScopy InChI
Affinity DataIC50: 340nMMore data for this Ligand-Target Pair
In DepthDetails
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM50599011(CHEMBL5204291 | US20230322715, Compound TR-FTO-09)copy SMILES
Affinity DataIC50: 350nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM50599019(CHEMBL5207797 | US20230322715, Compound TR-FTO-30)copy SMILES
Affinity DataIC50: 350nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C72GZPubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM50599019(CHEMBL5207797 | US20230322715, Compound TR-FTO-30)copy SMILES
Affinity DataIC50: 350nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM50599011(CHEMBL5204291 | US20230322715, Compound TR-FTO-09)copy SMILES
Affinity DataIC50: 350nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C72GZPubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM589235(US11555009, Compound 15 | US11555009, Compound 29)copy SMILES
Affinity DataIC50: 400nMMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM589238(US11555009, Compound 26)copy SMILES
Affinity DataIC50: 400nMAssay Description:The present invention provides a novel class of demethylase FTO inhibitors which inhibit FTO protein activity at very low concentration (typically IC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B92ZGUS Patent
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM50606686(CHEMBL5219336)copy SMILES
Affinity DataIC50: 430nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8X83PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM50599013(CHEMBL5199622 | US20230322715, Compound TR-FTO-44)copy SMILES
Affinity DataIC50: 440nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM50599029(CHEMBL5203668)copy SMILES
Affinity DataIC50: 440nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C72GZPubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM85848(CAS_172307 | Fiduxosin | NSC_172307)copy SMILEScopy InChI
Affinity DataIC50: 490nMMore data for this Ligand-Target Pair
In DepthDetails
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM589236(US11555009, Compound 17)copy SMILES
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
Ligand InfoMCE
PC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959NJKPubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM50417150(CHEMBL4461072)copy SMILEScopy InChI
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
In DepthDetails
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM50596051(CHEMBL5183243)copy SMILES
Affinity DataIC50: 570nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8XWGPubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM50594336(CHEMBL5176527)copy SMILES
Affinity DataIC50: 600nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959NJKPubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM50599018(CHEMBL5186890 | US20230322715, Compound TR-FTO-27)copy SMILES
Affinity DataIC50: 670nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM50599018(CHEMBL5186890 | US20230322715, Compound TR-FTO-27)copy SMILES
Affinity DataIC50: 670nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C72GZPubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM477000(US11555009, Compound 1)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:The present invention provides a novel class of demethylase FTO inhibitors which inhibit FTO protein activity at very low concentration (typically IC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B92ZGUS Patent
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM50594337(CHEMBL5176730)copy SMILES
Affinity DataIC50: 700nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959NJKPubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM50417859(CHEMBL5268705)copy SMILEScopy InChI
Affinity DataIC50: 750nMMore data for this Ligand-Target Pair
In DepthDetails
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM50606684(CHEMBL5220148)copy SMILES
Affinity DataIC50: 800nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8X83PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM50599022(CHEMBL5181285 | US20230322715, Compound TR-FTO-37)copy SMILES
Affinity DataIC50: 810nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM50599022(CHEMBL5181285 | US20230322715, Compound TR-FTO-37)copy SMILES
Affinity DataIC50: 810nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C72GZPubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM50599013(CHEMBL5199622 | US20230322715, Compound TR-FTO-44)copy SMILES
Affinity DataIC50: 830nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C72GZPubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM50599013(CHEMBL5199622 | US20230322715, Compound TR-FTO-44)copy SMILES
Affinity DataIC50: 830nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM50017226((R)-2-Amino-7-phosphono-heptanoic acid | 2-Amino-7...)copy SMILEScopy InChI
Affinity DataIC50: 850nMMore data for this Ligand-Target Pair
In DepthDetails
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM50599015(CHEMBL5177222 | US20230322715, Compound TR-FTO-14)copy SMILES
Affinity DataIC50: 870nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM50599015(CHEMBL5177222 | US20230322715, Compound TR-FTO-14)copy SMILES
Affinity DataIC50: 870nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C72GZPubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM50599030(CHEMBL5182180 | US20230322715, Compound TR-FTO-45)copy SMILES
Affinity DataIC50: 900nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM50594335(CHEMBL4436398)copy SMILES
Affinity DataIC50: 900nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959NJKPubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM50594340(CHEMBL5171501)copy SMILES
Affinity DataIC50: 900nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959NJKPubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM50594341(CHEMBL5173835)copy SMILES
Affinity DataIC50: 900nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959NJKPubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))TBA
LigandPNGBDBM50606685(CHEMBL5219099)copy SMILES
Affinity DataIC50: 900nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8X83PubMed
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