Compile Data Set for Download or QSAR
Found 17 of ic50 for UniProtKB: P00533
TargetEpidermal growth factor receptor [1-973](Homo sapiens (Human))
Anhui University of Chinese Medicine

LigandPNGBDBM152773(4-(3-Morpholinopropoxy)-N-(3-chloro-4-fluorophenyl...)copy SMILEScopy InChI
Affinity DataIC50: 10.4nMT: 2°CAssay Description:The experiments were performed according to the instructions of the manufacturer. The EGFR TK activity was performed using Kinase-Glo Plus luminescen...More data for this Ligand-Target Pair
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BindingDB Entry DOI: 10.7270/Q2JD4VJRPubMed
TargetEpidermal growth factor receptor [1-973](Homo sapiens (Human))
Anhui University of Chinese Medicine

LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)copy SMILEScopy InChI
Affinity DataIC50: 12.1nMT: 2°CAssay Description:The experiments were performed according to the instructions of the manufacturer. The EGFR TK activity was performed using Kinase-Glo Plus luminescen...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-973](Homo sapiens (Human))
Anhui University of Chinese Medicine

LigandPNGBDBM152779(4-(3-(Piperidin-1-yl)propoxy)-N-(3-chloro-4-fluoro...)copy SMILEScopy InChI
Affinity DataIC50: 15.4nMT: 2°CAssay Description:The experiments were performed according to the instructions of the manufacturer. The EGFR TK activity was performed using Kinase-Glo Plus luminescen...More data for this Ligand-Target Pair
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BindingDB Entry DOI: 10.7270/Q2JD4VJRPubMed
TargetEpidermal growth factor receptor [1-973](Homo sapiens (Human))
Anhui University of Chinese Medicine

LigandPNGBDBM152777(4-(3-(Piperidin-1-yl)propoxy)-N-(m-tolyl)-2-hydrox...)copy SMILEScopy InChI
Affinity DataIC50: 22.4nMT: 2°CAssay Description:The experiments were performed according to the instructions of the manufacturer. The EGFR TK activity was performed using Kinase-Glo Plus luminescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD4VJRPubMed
TargetEpidermal growth factor receptor [1-973](Homo sapiens (Human))
Anhui University of Chinese Medicine

LigandPNGBDBM152780(4-(3-(Piperidin-1-yl)propoxy)-N-(2-chloro-4-nitrop...)copy SMILEScopy InChI
Affinity DataIC50: 23nMT: 2°CAssay Description:The experiments were performed according to the instructions of the manufacturer. The EGFR TK activity was performed using Kinase-Glo Plus luminescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD4VJRPubMed
TargetEpidermal growth factor receptor [1-973](Homo sapiens (Human))
Anhui University of Chinese Medicine

LigandPNGBDBM152772(4-(3-Morpholinopropoxy)-N-(3-(trifluoromethyl)phen...)copy SMILEScopy InChI
Affinity DataIC50: 34.6nMT: 2°CAssay Description:The experiments were performed according to the instructions of the manufacturer. The EGFR TK activity was performed using Kinase-Glo Plus luminescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD4VJRPubMed
TargetEpidermal growth factor receptor [1-973](Homo sapiens (Human))
Anhui University of Chinese Medicine

LigandPNGBDBM152778(4-(3-(Piperidin-1-yl)propoxy)-N-(3-(trifluoromethy...)copy SMILEScopy InChI
Affinity DataIC50: 35.2nMT: 2°CAssay Description:The experiments were performed according to the instructions of the manufacturer. The EGFR TK activity was performed using Kinase-Glo Plus luminescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD4VJRPubMed
TargetEpidermal growth factor receptor [1-973](Homo sapiens (Human))
Anhui University of Chinese Medicine

LigandPNGBDBM152775(4-(3-(Piperidin-1-yl)propoxy)-N-(3-bromophenyl)-2-...)copy SMILEScopy InChI
Affinity DataIC50: 45.7nMT: 2°CAssay Description:The experiments were performed according to the instructions of the manufacturer. The EGFR TK activity was performed using Kinase-Glo Plus luminescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD4VJRPubMed
TargetEpidermal growth factor receptor [1-973](Homo sapiens (Human))
Anhui University of Chinese Medicine

LigandPNGBDBM152776(4-(3-(Piperidin-1-yl)propoxy)-N-(3-chlorophenyl)-2...)copy SMILEScopy InChI
Affinity DataIC50: 63.9nMT: 2°CAssay Description:The experiments were performed according to the instructions of the manufacturer. The EGFR TK activity was performed using Kinase-Glo Plus luminescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD4VJRPubMed
TargetEpidermal growth factor receptor [1-973](Homo sapiens (Human))
Anhui University of Chinese Medicine

LigandPNGBDBM152774(4-(3-Morpholinopropoxy)-N-(2-chloro-4-nitrophenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 84.8nMT: 2°CAssay Description:The experiments were performed according to the instructions of the manufacturer. The EGFR TK activity was performed using Kinase-Glo Plus luminescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD4VJRPubMed
TargetEpidermal growth factor receptor [1-973](Homo sapiens (Human))
Anhui University of Chinese Medicine

LigandPNGBDBM152769(4-(3-morpholinopropoxy)-N-(3-bromophenyl)-2-hydrox...)copy SMILEScopy InChI
Affinity DataIC50: 85.8nMT: 2°CAssay Description:The experiments were performed according to the instructions of the manufacturer. The EGFR TK activity was performed using Kinase-Glo Plus luminescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD4VJRPubMed
TargetEpidermal growth factor receptor [1-973](Homo sapiens (Human))
Anhui University of Chinese Medicine

LigandPNGBDBM152771(4-(3-Morpholinopropoxy)-N-(m-tolyl)-2-hydroxybenza...)copy SMILEScopy InChI
Affinity DataIC50: 142nMT: 2°CAssay Description:The experiments were performed according to the instructions of the manufacturer. The EGFR TK activity was performed using Kinase-Glo Plus luminescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD4VJRPubMed
TargetEpidermal growth factor receptor [1-973](Homo sapiens (Human))
Anhui University of Chinese Medicine

LigandPNGBDBM152770(4-(3-Morpholinopropoxy)-N-(3-chlorophenyl)-2-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 196nMT: 2°CAssay Description:The experiments were performed according to the instructions of the manufacturer. The EGFR TK activity was performed using Kinase-Glo Plus luminescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD4VJRPubMed
TargetEpidermal growth factor receptor [1-973](Homo sapiens (Human))
Anhui University of Chinese Medicine

LigandPNGBDBM50399540(FORETINIB | US10464902, Foretinib | US10882853, Co...)copy SMILEScopy InChI
Affinity DataIC50: 2.99E+3nMpH: 7.0 T: 2°CAssay Description:The c-Met kinase activity was evaluated by homogeneous time-resolved fluorescence (HTRF) assays. In a 384-well plate, 20 µg/mL (Glue, Tyr) 4:1 w...More data for this Ligand-Target Pair
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BindingDB Entry DOI: 10.7270/Q2BG2MPQPubMed
TargetEpidermal growth factor receptor [1-973](Homo sapiens (Human))
Anhui University of Chinese Medicine

LigandPNGBDBM191572(6-(3-chlorophenyl)pteridine-2,4,7-triamine (15) | ...)copy SMILEScopy InChI
Affinity DataIC50: 8.30E+3nMAssay Description:Single-point measurement analyses of Epiblastin A against a panel of 123 kinases was performed at Eurofins (former Milipore) using a radiometric-base...More data for this Ligand-Target Pair
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BindingDB Entry DOI: 10.7270/Q2GQ6WJDPubMed
TargetEpidermal growth factor receptor [1-973](Homo sapiens (Human))
Anhui University of Chinese Medicine

LigandPNGBDBM120816((Z)-4-(((3-fluoro-4-((6-methoxy-7-(3-morpholinopro...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMpH: 7.0 T: 2°CAssay Description:The c-Met kinase activity was evaluated by homogeneous time-resolved fluorescence (HTRF) assays. In a 384-well plate, 20 µg/mL (Glue, Tyr) 4:1 w...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2MPQPubMed
TargetEpidermal growth factor receptor [1-973](Homo sapiens (Human))
Anhui University of Chinese Medicine

LigandPNGBDBM110206(1-[2-(Dimethylamino)ethyl]-5-(2-hydroxy-4-methoxyb...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+5nMpH: 7.0Assay Description:EGFR was incubated with 8 mM MOPS (pH 7.0), 0.2 mM EDTA, 10 mM MnCl2, 0.1 mg/mL poly(Glu, Tyr) 4:1. MAPK1 was incubated with 25 mM Tris (pH 7.5), 0.0...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1BBKPubMed