Compile Data Set for Download or QSAR
Found 100 of kd data for polymerid = 7498
TargetAlpha-synuclein(Homo sapiens (Human))
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

US Patent
LigandPNGBDBM481157(US10906900, Reference 25a)copy SMILEScopy InChI
Affinity DataKd:  0.490nMAssay Description:Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC42NCUS Patent
TargetAlpha-synuclein(Homo sapiens (Human))
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

US Patent
LigandPNGBDBM481157(US10906900, Reference 25a)copy SMILEScopy InChI
Affinity DataKd:  0.490nMAssay Description:Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC42NCUS Patent
TargetAlpha-synuclein(Homo sapiens (Human))
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

US Patent
LigandPNGBDBM481149(US10906900, Reference 22a)copy SMILEScopy InChI
Affinity DataKd:  0.530nMAssay Description:Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC42NCUS Patent
TargetAlpha-synuclein(Homo sapiens (Human))
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

US Patent
LigandPNGBDBM481149(US10906900, Reference 22a)copy SMILEScopy InChI
Affinity DataKd:  0.530nMAssay Description:Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC42NCUS Patent
TargetAlpha-synuclein(Homo sapiens (Human))
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

US Patent
LigandPNGBDBM481158(US10906900, Reference 25b)copy SMILEScopy InChI
Affinity DataKd:  0.730nMAssay Description:Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC42NCUS Patent
TargetAlpha-synuclein(Homo sapiens (Human))
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

US Patent
LigandPNGBDBM481153(US10906900, Reference 22f)copy SMILEScopy InChI
Affinity DataKd:  0.790nMAssay Description:Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC42NCUS Patent
TargetAlpha-synuclein(Homo sapiens (Human))
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

US Patent
LigandPNGBDBM50545096(CHEMBL4637732)copy SMILEScopy InChI
Affinity DataKd:  1nMAssay Description:Binding affinity to human wlid-type alpha-synuclein by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FWWPubMed
TargetAlpha-synuclein(Homo sapiens (Human))
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

US Patent
LigandPNGBDBM481156(US10906900, Reference 22d)copy SMILEScopy InChI
Affinity DataKd:  1nMAssay Description:Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC42NCUS Patent
TargetAlpha-synuclein(Homo sapiens (Human))
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

US Patent
LigandPNGBDBM481156(US10906900, Reference 22d)copy SMILEScopy InChI
Affinity DataKd:  1nMAssay Description:Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC42NCUS Patent
TargetAlpha-synuclein(Homo sapiens (Human))
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

US Patent
LigandPNGBDBM481159(US10906900, Reference 25c)copy SMILEScopy InChI
Affinity DataKd:  1.27nMAssay Description:Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC42NCUS Patent
TargetAlpha-synuclein(Homo sapiens (Human))
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

US Patent
LigandPNGBDBM481150(US10906900, Reference 22b)copy SMILEScopy InChI
Affinity DataKd:  1.40nMAssay Description:Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC42NCUS Patent
TargetAlpha-synuclein(Homo sapiens (Human))
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

US Patent
LigandPNGBDBM481150(US10906900, Reference 22b)copy SMILEScopy InChI
Affinity DataKd:  1.40nMAssay Description:Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC42NCUS Patent
TargetAlpha-synuclein(Homo sapiens (Human))
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

US Patent
LigandPNGBDBM481160(US10906900, Reference 28)copy SMILEScopy InChI
Affinity DataKd:  2.40nMAssay Description:Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC42NCUS Patent
TargetAlpha-synuclein(Homo sapiens (Human))
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

US Patent
LigandPNGBDBM481160(US10906900, Reference 28)copy SMILEScopy InChI
Affinity DataKd:  2.40nMAssay Description:Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC42NCUS Patent
TargetAlpha-synuclein(Homo sapiens (Human))
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

US Patent
LigandPNGBDBM481151(US10906900, Reference 22c)copy SMILEScopy InChI
Affinity DataKd:  3.25nMAssay Description:Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC42NCUS Patent
TargetAlpha-synuclein(Homo sapiens (Human))
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

US Patent
LigandPNGBDBM481151(US10906900, Reference 22c)copy SMILEScopy InChI
Affinity DataKd:  3.25nMAssay Description:Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC42NCUS Patent
TargetAlpha-synuclein(Homo sapiens (Human))
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

US Patent
LigandPNGBDBM50614060(CHEMBL5270314)copy SMILES
Affinity DataKd:  3.80nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetAlpha-synuclein(Homo sapiens (Human))
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

US Patent
LigandPNGBDBM50545088(CHEMBL4633757)copy SMILEScopy InChI
Affinity DataKd:  8.20nMAssay Description:Binding affinity to human wlid-type alpha-synuclein by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FWWPubMed
TargetAlpha-synuclein(Homo sapiens (Human))
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

US Patent
LigandPNGBDBM50103964(CHEMBL3593932)copy SMILEScopy InChI
Affinity DataKd:  8.90nMAssay Description:Binding affinity to recombinant alpha-synuclein (unknown origin) expressed in Escherichia coli after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7WRCPubMed
TargetAlpha-synuclein(Homo sapiens (Human))
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

US Patent
LigandPNGBDBM50582842(CHEMBL5087695)copy SMILES
Affinity DataKd:  10nMAssay Description:Binding affinity to recombinant human alpha-syn aggregates assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7FBGPubMed
TargetAlpha-synuclein(Homo sapiens (Human))
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

US Patent
LigandPNGBDBM50545097(CHEMBL4634055)copy SMILEScopy InChI
Affinity DataKd:  11nMAssay Description:Binding affinity to human wlid-type alpha-synuclein by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FWWPubMed
TargetAlpha-synuclein(Homo sapiens (Human))
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

US Patent
LigandPNGBDBM50185987(2-(1-(6-((2-fluoroethyl)(methyl)amino)naphthalen-2...)copy SMILEScopy InChI
Affinity DataKd:  16.1nMAssay Description:Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC42NCUS Patent
TargetAlpha-synuclein(Homo sapiens (Human))
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

US Patent
LigandPNGBDBM50185987(2-(1-(6-((2-fluoroethyl)(methyl)amino)naphthalen-2...)copy SMILEScopy InChI
Affinity DataKd:  16.1nMAssay Description:Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC42NCUS Patent
TargetAlpha-synuclein(Homo sapiens (Human))
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

US Patent
LigandPNGBDBM50492518(Florbetapir | US10906900, AV45)copy SMILEScopy InChI
Affinity DataKd:  24.3nMAssay Description:Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC42NCUS Patent
TargetAlpha-synuclein(Homo sapiens (Human))
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

US Patent
LigandPNGBDBM50492518(Florbetapir | US10906900, AV45)copy SMILEScopy InChI
Affinity DataKd:  24.3nMAssay Description:Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC42NCUS Patent
TargetAlpha-synuclein(Homo sapiens (Human))
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

US Patent
LigandPNGBDBM50614041(CHEMBL5286480)copy SMILES
Affinity DataKd:  30nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetAlpha-synuclein(Homo sapiens (Human))
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

US Patent
LigandPNGBDBM50614041(CHEMBL5286480)copy SMILES
Affinity DataKd:  30nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetAlpha-synuclein(Homo sapiens (Human))
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

US Patent
LigandPNGBDBM50609392(CHEMBL5276896)copy SMILES
Affinity DataKd:  39nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetAlpha-synuclein(Homo sapiens (Human))
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

US Patent
LigandPNGBDBM50582831(CHEMBL5074716)copy SMILES
Affinity DataKd:  40nMAssay Description:Binding affinity to recombinant human alpha-syn aggregates assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7FBGPubMed
TargetAlpha-synuclein(Homo sapiens (Human))
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

US Patent
LigandPNGBDBM50614044(CHEMBL5283353)copy SMILES
Affinity DataKd:  40nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetAlpha-synuclein(Homo sapiens (Human))
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

US Patent
LigandPNGBDBM50545098(CHEMBL4644640)copy SMILEScopy InChI
Affinity DataKd:  47nMAssay Description:Binding affinity to human wlid-type alpha-synuclein by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FWWPubMed
TargetAlpha-synuclein(Homo sapiens (Human))
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

US Patent
LigandPNGBDBM50389294(CHEMBL2063787)copy SMILEScopy InChI
Affinity DataKd:  60nMAssay Description:Binding affinity to recombinant human alpha-syn aggregates assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7FBGPubMed
TargetAlpha-synuclein(Homo sapiens (Human))
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

US Patent
LigandPNGBDBM50610486(CHEMBL5290387)copy SMILES
Affinity DataKd:  68nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetAlpha-synuclein(Homo sapiens (Human))
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

US Patent
LigandPNGBDBM50582846(CHEMBL5088083)copy SMILES
Affinity DataKd:  70nMAssay Description:Binding affinity to recombinant human alpha-syn aggregates assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7FBGPubMed
TargetAlpha-synuclein(Homo sapiens (Human))
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

US Patent
LigandPNGBDBM50582840(CHEMBL5092684)copy SMILES
Affinity DataKd:  100nMAssay Description:Binding affinity to recombinant human alpha-syn aggregates assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7FBGPubMed
TargetAlpha-synuclein(Homo sapiens (Human))
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

US Patent
LigandPNGBDBM50545087(CHEMBL4639644)copy SMILEScopy InChI
Affinity DataKd:  105nMAssay Description:Binding affinity to human wlid-type alpha-synuclein by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FWWPubMed
TargetAlpha-synuclein(Homo sapiens (Human))
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

US Patent
LigandPNGBDBM50545092(CHEMBL4642469)copy SMILEScopy InChI
Affinity DataKd:  107nMAssay Description:Binding affinity to human wlid-type alpha-synuclein by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FWWPubMed
TargetAlpha-synuclein(Homo sapiens (Human))
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

US Patent
LigandPNGBDBM50545086(CHEMBL4648610)copy SMILEScopy InChI
Affinity DataKd:  112nMAssay Description:Binding affinity to human wlid-type alpha-synuclein by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FWWPubMed
TargetAlpha-synuclein(Homo sapiens (Human))
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

US Patent
LigandPNGBDBM50545090(CHEMBL4634968)copy SMILEScopy InChI
Affinity DataKd:  116nMAssay Description:Binding affinity to human wlid-type alpha-synuclein by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FWWPubMed
TargetAlpha-synuclein(Homo sapiens (Human))
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

US Patent
LigandPNGBDBM50582834(CHEMBL5086296)copy SMILES
Affinity DataKd:  140nMAssay Description:Binding affinity to recombinant human alpha-syn aggregates assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7FBGPubMed
TargetAlpha-synuclein(Homo sapiens (Human))
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

US Patent
LigandPNGBDBM50582841(CHEMBL5075163)copy SMILES
Affinity DataKd:  140nMAssay Description:Binding affinity to recombinant human alpha-syn aggregates assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7FBGPubMed
TargetAlpha-synuclein(Homo sapiens (Human))
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

US Patent
LigandPNGBDBM50582839(CHEMBL5072207)copy SMILES
Affinity DataKd:  150nMAssay Description:Binding affinity to recombinant human alpha-syn aggregates assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7FBGPubMed
TargetAlpha-synuclein(Homo sapiens (Human))
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

US Patent
LigandPNGBDBM50553261(CHEMBL4763384)copy SMILES
Affinity DataKd:  160nMAssay Description:Binding affinity to human alpha-synuclein (1-140 residues) expressed in Escherichia coli BL21(DE3) assessed as first dissociation constant by mass-sp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H998V9PubMed
TargetAlpha-synuclein(Homo sapiens (Human))
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

US Patent
LigandPNGBDBM50582827(CHEMBL5075837)copy SMILES
Affinity DataKd:  180nMAssay Description:Binding affinity to recombinant human alpha-syn aggregates assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7FBGPubMed
TargetAlpha-synuclein(Homo sapiens (Human))
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

US Patent
LigandPNGBDBM50553260(CHEMBL4748063)copy SMILES
Affinity DataKd:  190nMAssay Description:Binding affinity to alpha-synuclein (unknown origin) expressed in Escherichia coli BL21(DE3) pLysS by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H998V9PubMed
TargetAlpha-synuclein(Homo sapiens (Human))
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

US Patent
LigandPNGBDBM50582851(CHEMBL5085623)copy SMILES
Affinity DataKd:  250nMAssay Description:Binding affinity to recombinant human alpha-syn aggregates assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7FBGPubMed
TargetAlpha-synuclein(Homo sapiens (Human))
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

US Patent
LigandPNGBDBM50582849(CHEMBL5080710)copy SMILES
Affinity DataKd:  320nMAssay Description:Binding affinity to recombinant human alpha-syn aggregates assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7FBGPubMed
TargetAlpha-synuclein(Homo sapiens (Human))
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

US Patent
LigandPNGBDBM50545099(CHEMBL4647336)copy SMILEScopy InChI
Affinity DataKd:  332nMAssay Description:Binding affinity to human wlid-type alpha-synuclein by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FWWPubMed
TargetAlpha-synuclein(Homo sapiens (Human))
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

US Patent
LigandPNGBDBM50545093(CHEMBL4645133)copy SMILEScopy InChI
Affinity DataKd:  344nMAssay Description:Binding affinity to human wlid-type alpha-synuclein by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FWWPubMed
TargetAlpha-synuclein(Homo sapiens (Human))
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)

US Patent
LigandPNGBDBM50582844(CHEMBL5084363)copy SMILES
Affinity DataKd:  380nMAssay Description:Binding affinity to recombinant human alpha-syn aggregates assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7FBGPubMed
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