Compile Data Set for Download or QSAR
Found 40 of ec50 data for polymerid = 6098,6743
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))TBA
LigandPNGBDBM23954(5-[(2E,3aS,4R,5R,6aS)-5-hydroxy-4-[(1E,3S)-3-hydro...)copy SMILEScopy InChI
Affinity DataEC50:  0.300nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542SKFPubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))TBA
LigandPNGBDBM50169552(CHEMBL3804978)copy SMILEScopy InChI
Affinity DataEC50:  1.40nMAssay Description:Agonist activity at human EP1 receptor expressed in CHO cells assessed as increase in intracellular calcium level by fluorescence based analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125VKGPubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))TBA
LigandPNGBDBM35847((15S)-prostaglandin E2 | (5Z,11alpha,13E,15S)-11,1...)copy SMILEScopy InChI
Affinity DataEC50:  3.70nMAssay Description:Agonist activity at human EP1 receptor expressed in CHO cells assessed as increase in intracellular calcium level by fluorescence based analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125VKGPubMedDrugBank
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))TBA
LigandPNGBDBM62356(US9422273, 12b)copy SMILEScopy InChI
Affinity DataEC50:  20nMpH: 7.4 T: 2°CAssay Description:Ca2+ signaling studies were performed using a FLIPR TETRA system (Molecular Devices, Sunnyvale, Calif., USA) in the 384-format. This is a high-throug...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ076KUS Patent
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))TBA
LigandPNGBDBM240747(US9422273, 12e)copy SMILEScopy InChI
Affinity DataEC50:  20nMpH: 7.4 T: 2°CAssay Description:Ca2+ signaling studies were performed using a FLIPR TETRA system (Molecular Devices, Sunnyvale, Calif., USA) in the 384-format. This is a high-throug...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ076KUS Patent
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))TBA
LigandPNGBDBM184630(US9156810, (52, 53))copy SMILEScopy InChI
Affinity DataEC50:  27nMpH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing the human or feline FP receptor, or EP1, EP2, EP3, or EP4 receptors were washed with TME buffer, scraped from the bot...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6J5KUS Patent
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))TBA
LigandPNGBDBM240744(US9422273, 12a)copy SMILEScopy InChI
Affinity DataEC50:  47nMpH: 7.4 T: 2°CAssay Description:Ca2+ signaling studies were performed using a FLIPR TETRA system (Molecular Devices, Sunnyvale, Calif., USA) in the 384-format. This is a high-throug...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ076KUS Patent
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))TBA
LigandPNGBDBM240746(US9422273, 12d)copy SMILEScopy InChI
Affinity DataEC50:  63nMpH: 7.4 T: 2°CAssay Description:Ca2+ signaling studies were performed using a FLIPR TETRA system (Molecular Devices, Sunnyvale, Calif., USA) in the 384-format. This is a high-throug...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ076KUS Patent
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))TBA
LigandPNGBDBM240745(US9422273, 12c)copy SMILEScopy InChI
Affinity DataEC50:  70nMpH: 7.4 T: 2°CAssay Description:Ca2+ signaling studies were performed using a FLIPR TETRA system (Molecular Devices, Sunnyvale, Calif., USA) in the 384-format. This is a high-throug...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ076KUS Patent
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))TBA
LigandPNGBDBM50169550(CHEMBL3806130)copy SMILEScopy InChI
Affinity DataEC50:  97nMAssay Description:Agonist activity at human EP1 receptor expressed in CHO cells assessed as increase in intracellular calcium level by fluorescence based analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125VKGPubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))TBA
LigandPNGBDBM50169548(CHEMBL3805176)copy SMILEScopy InChI
Affinity DataEC50:  160nMAssay Description:Agonist activity at human EP1 receptor expressed in CHO cells assessed as increase in intracellular calcium level by fluorescence based analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125VKGPubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))TBA
LigandPNGBDBM50594971(15-AU-81 | 15AU81 | CHEBI:50861 | L-606 | LRX -15 ...)copy SMILES
Affinity DataEC50:  285nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542SKFPubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))TBA
LigandPNGBDBM50090136((Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-((E)-(R)-3-hy...)copy SMILEScopy InChI
Affinity DataEC50:  300nMAssay Description:Functional activity in RAT-1cells, transiently-transfected with human Prostaglandin E receptor EP1 (% of control ligand, 17-phi-PGE2=80%)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3CJXPubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))TBA
LigandPNGBDBM50035622((5Z,13E,15S)-9alpha,11alpha,15-trihydroxyprosta-5,...)copy SMILEScopy InChI
Affinity DataEC50:  600nMAssay Description:Functional activity in RAT-1cells, transiently-transfected with human Prostaglandin E receptor EP1 (% of control ligand, 17-phi-PGE2=80%)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3CJXPubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))TBA
LigandPNGBDBM50169546(CHEMBL3805693)copy SMILEScopy InChI
Affinity DataEC50:  700nMAssay Description:Agonist activity at human EP1 receptor expressed in CHO cells assessed as increase in intracellular calcium level by fluorescence based analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125VKGPubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))TBA
LigandPNGBDBM50085910((Z)-7-{(1R,2R,3R,5S)-2-[(E)-(R)-4-(3-Chloro-phenox...)copy SMILEScopy InChI
Affinity DataEC50:  760nMAssay Description:Functional activity in RAT-1cells, transiently-transfected with human Prostaglandin E receptor EP1 (% of control ligand, 17-phi-PGE2=80%)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3CJXPubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))TBA
LigandPNGBDBM50169549(CHEMBL3805169)copy SMILEScopy InChI
Affinity DataEC50:  970nMAssay Description:Agonist activity at human EP1 receptor expressed in CHO cells assessed as increase in intracellular calcium level by fluorescence based analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125VKGPubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))TBA
LigandPNGBDBM184630(US9156810, (52, 53))copy SMILEScopy InChI
Affinity DataEC50:  1.02E+3nMpH: 7.4 T: 2°CAssay Description:HEK-293 cells stably expressing the human or feline FP receptor, or EP1, EP2, EP3, or EP4 receptors were washed with TME buffer, scraped from the bot...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6J5KUS Patent
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))TBA
LigandPNGBDBM50454060(CHEMBL4208379)copy SMILEScopy InChI
Affinity DataEC50:  2.00E+3nMAssay Description:Agonist activity at recombinant human EP1 receptor expressed in CHO cells assessed as increase in intracellular calcium level measured at 3 secs time...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3VZ5PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))TBA
LigandPNGBDBM50545401(CHEMBL4649582)copy SMILEScopy InChI
Affinity DataEC50:  2.35E+3nMAssay Description:Agonist activity at human EP1 receptor expressed in HEK293 cells by calcium-5 dye based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7214PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))TBA
LigandPNGBDBM50169547(CHEMBL3805044)copy SMILEScopy InChI
Affinity DataEC50:  4.20E+3nMAssay Description:Agonist activity at human EP1 receptor expressed in CHO cells assessed as increase in intracellular calcium level by fluorescence based analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125VKGPubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))TBA
LigandPNGBDBM50156473(CHEMBL3793724)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human EP1 receptor expressed in CHO cells assessed as intracellular Ca2+ level by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41T90PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))TBA
LigandPNGBDBM50156472(CHEMBL3793167)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human EP1 receptor expressed in CHO cells assessed as intracellular Ca2+ level by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41T90PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))TBA
LigandPNGBDBM50156544(CHEMBL3793209)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human EP1 receptor expressed in CHO cells assessed as increase in intracellular calcium level by fluorescence based analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125VKGPubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))TBA
LigandPNGBDBM50156530(CHEMBL3793009)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human EP1 receptor expressed in CHO cells assessed as intracellular Ca2+ level by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41T90PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))TBA
LigandPNGBDBM50156539(CHEMBL3793892)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human EP1 receptor expressed in CHO cells assessed as intracellular Ca2+ level by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41T90PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))TBA
LigandPNGBDBM50085914(7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-((S)-3-hydroxy-oc...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Functional activity in RAT-1cells, transiently-transfected with human Prostaglandin E receptor EP1 (% of control ligand, 17-phi-PGE2<50%)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3CJXPubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))TBA
LigandPNGBDBM50156474(CHEMBL3793515)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human EP1 receptor expressed in CHO cells assessed as intracellular Ca2+ level by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41T90PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))TBA
LigandPNGBDBM50156529(CHEMBL3794226)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human EP1 receptor expressed in CHO cells assessed as intracellular Ca2+ level by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41T90PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))TBA
LigandPNGBDBM50156528(CHEMBL3794185)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human EP1 receptor expressed in CHO cells assessed as intracellular Ca2+ level by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41T90PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))TBA
LigandPNGBDBM50156491(CHEMBL3792668)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human EP1 receptor expressed in CHO cells assessed as intracellular Ca2+ level by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41T90PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))TBA
LigandPNGBDBM50545404(CHEMBL4633041)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human EP1 receptor expressed in HEK293 cells by calcium-5 dye based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7214PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))TBA
LigandPNGBDBM50545403(CHEMBL4640635)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human EP1 receptor expressed in HEK293 cells by calcium-5 dye based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7214PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))TBA
LigandPNGBDBM50545402(CHEMBL4640391)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human EP1 receptor expressed in HEK293 cells by calcium-5 dye based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7214PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))TBA
LigandPNGBDBM50545399(CHEMBL4635212)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human EP1 receptor expressed in HEK293 cells by calcium-5 dye based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7214PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))TBA
LigandPNGBDBM50545400(CHEMBL4647921)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human EP1 receptor expressed in HEK293 cells by calcium-5 dye based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C7214PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))TBA
LigandPNGBDBM50085911(7-{(1R,2R,3R,5S)-2-[(R)-4-(3-Chloro-phenoxy)-3-hyd...)copy SMILEScopy InChI
Affinity DataEC50:  1.90E+4nMAssay Description:Functional activity in RAT-1cells, transiently-transfected with human Prostaglandin E receptor EP1 (% of control ligand, 17-phi-PGE2=100%)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3CJXPubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))TBA
LigandPNGBDBM50090133((Z)-7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(E)-(S)-3-hy...)copy SMILEScopy InChI
Affinity DataEC50: >2.00E+4nMAssay Description:Functional activity in RAT-1cells, transiently-transfected with human Prostaglandin E receptor EP1 (% of control ligand, 17-phi-PGE2<50%)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3CJXPubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))TBA
LigandPNGBDBM50090137(7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-((R)-3-hydroxy-4,...)copy SMILEScopy InChI
Affinity DataEC50: >2.00E+4nMAssay Description:Functional activity in RAT-1cells, transiently-transfected with human Prostaglandin E receptor EP1 (% of control ligand, 17-phi-PGE2<20%)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3CJXPubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))TBA
LigandPNGBDBM50090140(7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(R)-3-hydroxy-5-...)copy SMILEScopy InChI
Affinity DataEC50:  3.00E+4nMAssay Description:Functional activity in RAT-1cells, transiently-transfected with human Prostaglandin E receptor EP1 (% of control ligand, 17-phi-PGE2=100%)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3CJXPubMed