Compile Data Set for Download or QSAR
Found 979 of ic50 data for polymerid = 1413,4970
LigandPNGBDBM50579997(CHEMBL5085615)copy SMILES
Affinity DataIC50: 1nMAssay Description:Inhibition of PTPN2 (unknown origin) by Mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB49MHPubMed
LigandPNGBDBM50579998(CHEMBL5084112)copy SMILES
Affinity DataIC50: 1nMAssay Description:Inhibition of PTPN2 (unknown origin) by Mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB49MHPubMed
LigandPNGBDBM50579999(CHEMBL5075269)copy SMILES
Affinity DataIC50: 1nMAssay Description:Inhibition of PTPN2 (unknown origin) by Mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB49MHPubMed
LigandPNGBDBM50580000(CHEMBL5076419)copy SMILES
Affinity DataIC50: 1nMAssay Description:Inhibition of PTPN2 (unknown origin) by Mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB49MHPubMed
LigandPNGBDBM50580001(CHEMBL5087544)copy SMILES
Affinity DataIC50: 1nMAssay Description:Inhibition of PTPN2 (unknown origin) by Mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB49MHPubMed
LigandPNGBDBM50580002(CHEMBL5084380)copy SMILES
Affinity DataIC50: 1nMAssay Description:Inhibition of PTPN2 (unknown origin) by Mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB49MHPubMed
LigandPNGBDBM50580003(CHEMBL5080612)copy SMILES
Affinity DataIC50: 1nMAssay Description:Inhibition of PTPN2 (unknown origin) by Mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB49MHPubMed
LigandPNGBDBM50580005(CHEMBL5093253)copy SMILES
Affinity DataIC50: 1nMAssay Description:Inhibition of PTPN2 (unknown origin) by Mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB49MHPubMed
LigandPNGBDBM50579994(CHEMBL5070507)copy SMILES
Affinity DataIC50: 1nMAssay Description:Inhibition of PTPN2 (unknown origin) by Mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB49MHPubMed
LigandPNGBDBM50579995(CHEMBL5085502)copy SMILES
Affinity DataIC50: 1nMAssay Description:Inhibition of PTPN2 (unknown origin) by Mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB49MHPubMed
LigandPNGBDBM50579996(CHEMBL5092308)copy SMILES
Affinity DataIC50: 1nMAssay Description:Inhibition of PTPN2 (unknown origin) by Mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB49MHPubMed
LigandPNGBDBM13599(3-{4-[2-(1H-1,2,3-benzotriazol-1-yl)-3-{4-[difluor...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of TCPTP (unknown origin) by UV/Vis spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z756PPubMed
LigandPNGBDBM13599(3-{4-[2-(1H-1,2,3-benzotriazol-1-yl)-3-{4-[difluor...)copy SMILEScopy InChI
Affinity DataIC50: 3nMpH: 6.3 T: 2°CAssay Description:Hydrolysis of substrate FDP was monitored continuously on a Cytofluor microplate reader with excitation and emission wavelengths set at 440 and 515 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX19XSPubMed
LigandPNGBDBM13599(3-{4-[2-(1H-1,2,3-benzotriazol-1-yl)-3-{4-[difluor...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against T cell protein tyrosine phosphataseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M9404PubMed
LigandPNGBDBM50142323(CHEMBL267488 | [(4-{2-Benzotriazol-1-yl-3-[3-bromo...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibitory activity against T cell protein tyrosine phosphataseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M9404PubMed
LigandPNGBDBM13596(({4-[2-(1H-1,2,3-benzotriazol-1-yl)-3-{4-[difluoro...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibitory activity against T cell protein tyrosine phosphataseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M9404PubMed
LigandPNGBDBM13595(({4-[2-(1H-1,2,3-benzotriazol-1-yl)-3-{4-[difluoro...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against T cell protein tyrosine phosphataseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M9404PubMed
LigandPNGBDBM50580004(CHEMBL5089047)copy SMILES
Affinity DataIC50: 10nMAssay Description:Inhibition of PTPN2 (unknown origin) by Mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB49MHPubMed
LigandPNGBDBM50142335(CHEMBL274435 | [(4-{4-Benzotriazol-1-yl-5-[4-(difl...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against T cell protein tyrosine phosphataseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M9404PubMed
LigandPNGBDBM13595(({4-[2-(1H-1,2,3-benzotriazol-1-yl)-3-{4-[difluoro...)copy SMILEScopy InChI
Affinity DataIC50: 11nMpH: 6.3 T: 2°CAssay Description:Hydrolysis of substrate FDP was monitored continuously on a Cytofluor microplate reader with excitation and emission wavelengths set at 440 and 515 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX19XSPubMed
LigandPNGBDBM50115732(CHEMBL294467 | Sodium vanadate)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant human TCPTP using pNPP as substrate measured after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7N1MPubMed
LigandPNGBDBM50391109(CHEMBL179166 | Sodium orthovanadate (SOV) | Vanada...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant TCPTP assessed as inhibition of hydrolysis of p-nitrophenol after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1DRSPubMed
LigandPNGBDBM50391109(CHEMBL179166 | Sodium orthovanadate (SOV) | Vanada...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant TCPTP (unknown origin) using pNPP as substrate measured after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FR0024PubMed
LigandPNGBDBM50142328(4-{1-Benzotriazol-1-yl-1-[4-(difluoro-phosphono-me...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibitory activity against T cell protein tyrosine phosphataseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M9404PubMed
LigandPNGBDBM50142324(({4-[2-Benzotriazol-1-yl-3-[4-(difluoro-phosphono-...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibitory activity against T cell protein tyrosine phosphataseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M9404PubMed
LigandPNGBDBM13603(6-{4-[2-(1H-1,2,3-benzotriazol-1-yl)-3-{4-[difluor...)copy SMILEScopy InChI
Affinity DataIC50: 17nMpH: 6.3 T: 2°CAssay Description:Hydrolysis of substrate FDP was monitored continuously on a Cytofluor microplate reader with excitation and emission wavelengths set at 440 and 515 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX19XSPubMed
LigandPNGBDBM50391109(CHEMBL179166 | Sodium orthovanadate (SOV) | Vanada...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of TCPTP (unknown origin) using pNPP as substrate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9G90PubMed
LigandPNGBDBM50142329(({4-[2-Benzotriazol-1-yl-3-[4-(difluoro-phosphono-...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibitory activity against T cell protein tyrosine phosphataseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M9404PubMed
LigandPNGBDBM13602(6-{4-[2-(1H-1,2,3-benzotriazol-1-yl)-3-{4-[difluor...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against T cell protein tyrosine phosphataseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M9404PubMed
LigandPNGBDBM13601(5-{4-[2-(1H-1,2,3-benzotriazol-1-yl)-3-{4-[difluor...)copy SMILEScopy InChI
Affinity DataIC50: 20nMpH: 6.3 T: 2°CAssay Description:Hydrolysis of substrate FDP was monitored continuously on a Cytofluor microplate reader with excitation and emission wavelengths set at 440 and 515 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX19XSPubMed
LigandPNGBDBM50142330(CHEMBL8662 | [(4-{2-Benzothiazol-2-yl-2-benzotriaz...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against T cell protein tyrosine phosphataseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M9404PubMed
LigandPNGBDBM13602(6-{4-[2-(1H-1,2,3-benzotriazol-1-yl)-3-{4-[difluor...)copy SMILEScopy InChI
Affinity DataIC50: 20nMpH: 6.3 T: 2°CAssay Description:Hydrolysis of substrate FDP was monitored continuously on a Cytofluor microplate reader with excitation and emission wavelengths set at 440 and 515 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX19XSPubMed
LigandPNGBDBM13605(6-{4-[2-(1H-1,2,3-benzotriazol-1-yl)-3-{4-[difluor...)copy SMILEScopy InChI
Affinity DataIC50: 21nMpH: 6.3 T: 2°CAssay Description:Hydrolysis of substrate FDP was monitored continuously on a Cytofluor microplate reader with excitation and emission wavelengths set at 440 and 515 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX19XSPubMed
LigandPNGBDBM13598(({4-[2-(1H-1,2,3-benzotriazol-1-yl)-2-phenyl-3-(4-...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibitory activity against T cell protein tyrosine phosphataseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M9404PubMed
LigandPNGBDBM50228024(3-fluoro-N-{1-[5-(3-phenyl-propyl)-1H-imidazol-2-y...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of TCPTP by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7GCQPubMed
LigandPNGBDBM13598(({4-[2-(1H-1,2,3-benzotriazol-1-yl)-2-phenyl-3-(4-...)copy SMILEScopy InChI
Affinity DataIC50: 24nMpH: 6.3 T: 2°CAssay Description:Hydrolysis of substrate FDP was monitored continuously on a Cytofluor microplate reader with excitation and emission wavelengths set at 440 and 515 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX19XSPubMed
TargetTyrosine-protein phosphatase non-receptor type 2 [V121L](Homo sapiens (Human))
Merck Frosst Center for Therapeutic Research

LigandPNGBDBM13814(({4-[(4E)-2-(1H-1,2,3-benzotriazol-1-yl)-2-[4-(met...)copy SMILEScopy InChI
Affinity DataIC50: 24nMpH: 6.3 T: 2°CAssay Description:Hydrolysis of substrate FDP was monitored continuously on a Cytofluor microplate reader with excitation and emission wavelengths set at 440 and 515 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53J3VPubMed
LigandPNGBDBM50308844(3-Fluoro-N-{1-{(R)-4-[2-(2-methanesulfonyl-phenoxy...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of TCPTPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P60MBPubMed
LigandPNGBDBM14269((S)-isothiazolidinone | IZD deriv. 2 | N-[(1S)-1-(...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of TCPTPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P60MBPubMed
LigandPNGBDBM50228013(3-fluoro-N-{1-{(R)-5-[2-(3-methanesulfonyl-phenoxy...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of TCPTP by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7GCQPubMed
LigandPNGBDBM199179(US9217012, 8)copy SMILEScopy InChI
Affinity DataIC50: 26nMpH: 7.0 T: 2°CAssay Description:PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in DMG buffer (50 mM DMG, pH 7.0, 1 mM EDTA, 150 mM NaCl, 2 mM DTT, 0.1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FX788HUS Patent
LigandPNGBDBM50171117(2-(4-(N-(3-bromo-4-(difluoro(phosphono)methyl)benz...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of TCPTPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P60MBPubMed
LigandPNGBDBM50142325(CHEMBL273474 | [(4-{2-Benzotriazol-1-yl-3-[4-(difl...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibitory activity against T cell protein tyrosine phosphataseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M9404PubMed
LigandPNGBDBM13600(5-{4-[2-(1H-1,2,3-benzotriazol-1-yl)-3-{4-[difluor...)copy SMILEScopy InChI
Affinity DataIC50: 31nMpH: 6.3 T: 2°CAssay Description:Hydrolysis of substrate FDP was monitored continuously on a Cytofluor microplate reader with excitation and emission wavelengths set at 440 and 515 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX19XSPubMed
LigandPNGBDBM50308854(CHEMBL590235 | [7-(4-{1-Benzotriazol-1-yl-2-[4-(di...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of TCPTPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P60MBPubMed
LigandPNGBDBM13604(6-{4-[2-(1H-1,2,3-benzotriazol-1-yl)-3-{4-[difluor...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibitory activity against T cell protein tyrosine phosphataseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M9404PubMed
LigandPNGBDBM50535627(CHEMBL4542052)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of human FLAG-tagged TCPTP (1 to 296) expressed in Escherichia coli using fluorescein diphosphate as substrate by fluorescence based metho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2280C4BPubMed
LigandPNGBDBM13604(6-{4-[2-(1H-1,2,3-benzotriazol-1-yl)-3-{4-[difluor...)copy SMILEScopy InChI
Affinity DataIC50: 36nMpH: 6.3 T: 2°CAssay Description:Hydrolysis of substrate FDP was monitored continuously on a Cytofluor microplate reader with excitation and emission wavelengths set at 440 and 515 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX19XSPubMed
LigandPNGBDBM13604(6-{4-[2-(1H-1,2,3-benzotriazol-1-yl)-3-{4-[difluor...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of TCPTP (unknown origin) by UV/Vis spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z756PPubMed
LigandPNGBDBM50228038(3-fluoro-N-{1-[(R)-5-(2-fluoro-benzyl)-4,5-dihydro...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of TCPTP by pNPP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7GCQPubMed
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