TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.
Curated by ChEMBL
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.
Curated by ChEMBL
Affinity DataIC50: 154nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5B SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.
Curated by ChEMBL
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5B SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.
Curated by ChEMBL
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.
Curated by ChEMBL
Affinity DataIC50: 234nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5B SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.
Curated by ChEMBL
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.
Curated by ChEMBL
Affinity DataIC50: 240nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5B SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.
Curated by ChEMBL
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5B SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.
Curated by ChEMBL
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.
Curated by ChEMBL
Affinity DataIC50: 270nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5B SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.
Curated by ChEMBL
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.
Curated by ChEMBL
Affinity DataIC50: 280nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5B SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.
Curated by ChEMBL
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5B SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.
Curated by ChEMBL
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.
Curated by ChEMBL
Affinity DataIC50: 330nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5B SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.
Curated by ChEMBL
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.
Curated by ChEMBL
Affinity DataIC50: 350nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5B SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.
Curated by ChEMBL
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.
Curated by ChEMBL
Affinity DataIC50: 390nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5B SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.
Curated by ChEMBL
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.
Curated by ChEMBL
Affinity DataIC50: 460nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5B SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.
Curated by ChEMBL
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.
Curated by ChEMBL
Affinity DataIC50: 620nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5B SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.
Curated by ChEMBL
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.
Curated by ChEMBL
Affinity DataIC50: 660nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5B SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.
Curated by ChEMBL
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.
Curated by ChEMBL
Affinity DataKi: 340nM IC50: 750nMAssay Description:For competition-based fluorescence polarization assays, the ability of the test compounds to displace fluorophore-labeled peptides from their respect...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.
Curated by ChEMBL
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.
Curated by ChEMBL
Affinity DataKi: 390nM IC50: 860nMAssay Description:For competition-based fluorescence polarization assays, the ability of the test compounds to displace fluorophore-labeled peptides from their respect...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.
Curated by ChEMBL
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMAssay Description:Binding affinity to MBP-tagged recombinant STAT5b-SH2 domain (unknown origin) using carboxyfluoresceine-labeled phosphotyrosine octapeptide incubated...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.
Curated by ChEMBL
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.
Curated by ChEMBL
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of 5-carboxyfluorescein-GpYLVLDKW-OH binding to STAT5B SH2 domain (unknown origin) pre-incubated for 1 hr before fluorescent-labelled pept...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.
Curated by ChEMBL
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.
Curated by ChEMBL
Affinity DataIC50: 2.90E+3nMAssay Description:Binding affinity to MBP-tagged recombinant STAT5b-SH2 domain (unknown origin) using carboxyfluoresceine-labeled phosphotyrosine octapeptide incubated...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.
Curated by ChEMBL
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.
Curated by ChEMBL
Affinity DataIC50: 1.04E+4nMAssay Description:Inhibition of 5-carboxyfluorescein-GpYLVLDKW-OH binding to STAT5B SH2 domain (unknown origin) pre-incubated for 1 hr before fluorescent-labelled pept...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.
Curated by ChEMBL
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.
Curated by ChEMBL
Affinity DataIC50: 1.27E+4nMAssay Description:Inhibition of 5-carboxyfluorescein-GpYLVLDKW-OH binding to STAT5B SH2 domain (unknown origin) pre-incubated for 1 hr before fluorescent-labelled pept...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.
Curated by ChEMBL
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.
Curated by ChEMBL
Affinity DataIC50: 3.70E+4nMAssay Description:Binding affinity to MBP-tagged recombinant STAT5b-SH2 domain (unknown origin) using carboxyfluoresceine-labeled phosphotyrosine octapeptide incubated...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.
Curated by ChEMBL
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.
Curated by ChEMBL
Affinity DataKi: 9.60E+4nM IC50: 1.96E+5nMAssay Description:For competition-based fluorescence polarization assays, the ability of the test compounds to displace fluorophore-labeled peptides from their respect...More data for this Ligand-Target Pair