Compile Data Set for Download or QSAR
Found 23 of ic50 data for polymerid = 7388
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.

Curated by ChEMBL
LigandPNGBDBM50267892(CHEMBL4088092)copy SMILEScopy InChI
Affinity DataIC50: 154nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5B SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q20RBPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.

Curated by ChEMBL
LigandPNGBDBM50267888(CHEMBL4104462)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5B SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q20RBPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.

Curated by ChEMBL
LigandPNGBDBM50267877(CHEMBL4103576)copy SMILEScopy InChI
Affinity DataIC50: 234nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5B SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q20RBPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.

Curated by ChEMBL
LigandPNGBDBM50267890(CHEMBL4085646)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5B SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q20RBPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.

Curated by ChEMBL
LigandPNGBDBM50267878(CHEMBL4104019)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5B SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q20RBPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.

Curated by ChEMBL
LigandPNGBDBM50267889(CHEMBL4080219)copy SMILEScopy InChI
Affinity DataIC50: 270nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5B SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q20RBPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.

Curated by ChEMBL
LigandPNGBDBM50267885(CHEMBL4066274)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5B SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q20RBPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.

Curated by ChEMBL
LigandPNGBDBM50267884(CHEMBL4086096)copy SMILEScopy InChI
Affinity DataIC50: 290nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5B SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q20RBPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.

Curated by ChEMBL
LigandPNGBDBM50267887(CHEMBL4077592)copy SMILEScopy InChI
Affinity DataIC50: 330nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5B SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q20RBPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.

Curated by ChEMBL
LigandPNGBDBM50267886(CHEMBL4093849)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5B SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q20RBPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.

Curated by ChEMBL
LigandPNGBDBM50267876(CHEMBL4080740)copy SMILEScopy InChI
Affinity DataIC50: 390nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5B SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q20RBPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.

Curated by ChEMBL
LigandPNGBDBM50267862(CHEMBL4075745)copy SMILEScopy InChI
Affinity DataIC50: 460nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5B SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q20RBPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.

Curated by ChEMBL
LigandPNGBDBM50267875(CHEMBL4062751)copy SMILEScopy InChI
Affinity DataIC50: 620nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5B SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q20RBPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.

Curated by ChEMBL
LigandPNGBDBM50267891(CHEMBL4076474)copy SMILEScopy InChI
Affinity DataIC50: 660nMAssay Description:Displacement of 5-carboxyfluorescein-GY(PO3H2)LVLDKW from STAT5B SH2 domain (unknown origin) pretreated for 1 hr followed by fluorescent tracer addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q20RBPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.

Curated by ChEMBL
LigandPNGBDBM165192(4-((8-Methylnonanamido)methyl)-1,2-phenylene bis(d...)copy SMILEScopy InChI
Affinity DataKi:  340nM IC50: 750nMAssay Description:For competition-based fluorescence polarization assays, the ability of the test compounds to displace fluorophore-labeled peptides from their respect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P55M8GPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.

Curated by ChEMBL
LigandPNGBDBM165193(4-(Nonanamidomethyl)-1,2-phenylene bis(dihydrogen ...)copy SMILEScopy InChI
Affinity DataKi:  390nM IC50: 860nMAssay Description:For competition-based fluorescence polarization assays, the ability of the test compounds to displace fluorophore-labeled peptides from their respect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P55M8GPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.

Curated by ChEMBL
LigandPNGBDBM50514407(CHEMBL4483038)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Binding affinity to MBP-tagged recombinant STAT5b-SH2 domain (unknown origin) using carboxyfluoresceine-labeled phosphotyrosine octapeptide incubated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8C0RPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.

Curated by ChEMBL
LigandPNGBDBM50240455(CHEMBL1253351)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of 5-carboxyfluorescein-GpYLVLDKW-OH binding to STAT5B SH2 domain (unknown origin) pre-incubated for 1 hr before fluorescent-labelled pept...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66P7FPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.

Curated by ChEMBL
LigandPNGBDBM50514413(CHEMBL4555061)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+3nMAssay Description:Binding affinity to MBP-tagged recombinant STAT5b-SH2 domain (unknown origin) using carboxyfluoresceine-labeled phosphotyrosine octapeptide incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8C0RPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.

Curated by ChEMBL
LigandPNGBDBM50000029(4-Methyl-8-{4-methyl-3-[3-(3-{3-[2-methyl-5-(4,6,8...)copy SMILEScopy InChI
Affinity DataIC50: 1.04E+4nMAssay Description:Inhibition of 5-carboxyfluorescein-GpYLVLDKW-OH binding to STAT5B SH2 domain (unknown origin) pre-incubated for 1 hr before fluorescent-labelled pept...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66P7FPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.

Curated by ChEMBL
LigandPNGBDBM50118228(5,7-Disulfo-4-(3-{3-[3-(4,6,8-trisulfo-naphthalen-...)copy SMILEScopy InChI
Affinity DataIC50: 1.27E+4nMAssay Description:Inhibition of 5-carboxyfluorescein-GpYLVLDKW-OH binding to STAT5B SH2 domain (unknown origin) pre-incubated for 1 hr before fluorescent-labelled pept...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66P7FPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.

Curated by ChEMBL
LigandPNGBDBM50514414(CHEMBL4439829)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+4nMAssay Description:Binding affinity to MBP-tagged recombinant STAT5b-SH2 domain (unknown origin) using carboxyfluoresceine-labeled phosphotyrosine octapeptide incubated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8C0RPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
Institute of Organic Chemistry, Leipzig University, Johannisallee 29, 04103 Leipzig, Germany.

Curated by ChEMBL
LigandPNGBDBM165191(2-Methoxy-4-(nonanamidomethyl)phenyl dihydrogen ph...)copy SMILEScopy InChI
Affinity DataKi:  9.60E+4nM IC50: 1.96E+5nMAssay Description:For competition-based fluorescence polarization assays, the ability of the test compounds to displace fluorophore-labeled peptides from their respect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P55M8GPubMed