Compile Data Set for Download or QSAR
Found 185 of ki data for polymerid = 4981
TargetAurora kinase B(Homo sapiens (Human))
Xuzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50241089(2-(ethyl(3-(4-(5-(2-(3-fluorophenylamino)-2-oxoeth...)copy SMILEScopy InChI
Affinity DataKi:  0.370nMAssay Description:Inhibition of aurora B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26111Q1PubMed
TargetAurora kinase B(Homo sapiens (Human))
Xuzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50315769(3-(4-(4-(2-(3-((dimethylamino)methyl)phenyl)-1H-py...)copy SMILEScopy InChI
Affinity DataKi:  0.380nMAssay Description:Competitive inhibition of Aurora B ATP binding siteMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27082CKPubMed
TargetAurora kinase B(Homo sapiens (Human))
Xuzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50315769(3-(4-(4-(2-(3-((dimethylamino)methyl)phenyl)-1H-py...)copy SMILEScopy InChI
Affinity DataKi:  0.380nMAssay Description:Competitive inhibition of human Aurora B ATP binding site by rapid dilution methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27082CKPubMed
TargetAurora kinase B(Homo sapiens (Human))
Xuzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50442149(CHEMBL2441267)copy SMILEScopy InChI
Affinity DataKi:  0.501nMAssay Description:Inhibition of Aurora-B (unknown origin) using 5FAM-PKAtide as substrate after 120 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P61Z7PubMed
TargetAurora kinase B(Homo sapiens (Human))
Xuzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50277679(CHEMBL484006 | N-(4-(4-(4-tert-butylpiperazin-1-yl...)copy SMILEScopy InChI
Affinity DataKi:  0.800nMAssay Description:Inhibition of Aurora-B by time dependent kinetic studyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7944PubMed
TargetAurora kinase B(Homo sapiens (Human))
Xuzhou Medical College

Curated by ChEMBL
LigandPNGBDBM26277(N-(3,5-difluorophenyl)-2-{3-[(7-{3-[4-(hydroxymeth...)copy SMILEScopy InChI
Affinity DataKi:  1nM ΔG°:  -50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W24PubMed
TargetAurora kinase B(Homo sapiens (Human))
Xuzhou Medical College

Curated by ChEMBL
LigandPNGBDBM26295(CHEMBL214849 | N-(2,3-difluorophenyl)-2-{3-[(7-{3-...)copy SMILEScopy InChI
Affinity DataKi: <1nM ΔG°: <-50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W24PubMed
TargetAurora kinase B(Homo sapiens (Human))
Xuzhou Medical College

Curated by ChEMBL
LigandPNGBDBM26308(4-aminopyrazole quinazoline, 8 | N-(2,3-difluoroph...)copy SMILEScopy InChI
Affinity DataKi: <1nM ΔG°: <-50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ64C7PubMed
TargetAurora kinase B(Homo sapiens (Human))
Xuzhou Medical College

Curated by ChEMBL
LigandPNGBDBM26307(4-aminopyrazole quinazoline, 7 | N-(3-fluorophenyl...)copy SMILEScopy InChI
Affinity DataKi: <1nM ΔG°: <-50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ64C7PubMed
TargetAurora kinase B(Homo sapiens (Human))
Xuzhou Medical College

Curated by ChEMBL
LigandPNGBDBM26284(N-(2,3-difluorophenyl)-2-{3-[(7-{3-[(2R)-2-(hydrox...)copy SMILEScopy InChI
Affinity DataKi:  1nM ΔG°:  -50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W24PubMed
TargetAurora kinase B(Homo sapiens (Human))
Xuzhou Medical College

Curated by ChEMBL
LigandPNGBDBM26285(N-(2,3-difluorophenyl)-2-{3-[(7-{3-[(2S)-2-(hydrox...)copy SMILEScopy InChI
Affinity DataKi: <1nM ΔG°: <-50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W24PubMed
TargetAurora kinase B(Homo sapiens (Human))
Xuzhou Medical College

Curated by ChEMBL
LigandPNGBDBM26286(N-(2,3-difluorophenyl)-2-{3-[(7-{3-[4-(2-hydroxyet...)copy SMILEScopy InChI
Affinity DataKi: <1nM ΔG°: <-50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W24PubMed
TargetAurora kinase B(Homo sapiens (Human))
Xuzhou Medical College

Curated by ChEMBL
LigandPNGBDBM26287(N-(2,3-difluorophenyl)-2-[3-({7-[3-(4-hydroxypiper...)copy SMILEScopy InChI
Affinity DataKi: <1nM ΔG°: <-50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W24PubMed
TargetAurora kinase B(Homo sapiens (Human))
Xuzhou Medical College

Curated by ChEMBL
LigandPNGBDBM26288(N-(2,3-difluorophenyl)-2-{3-[(7-{3-[4-(2-hydroxyet...)copy SMILEScopy InChI
Affinity DataKi: <1nM ΔG°: <-50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W24PubMed
TargetAurora kinase B(Homo sapiens (Human))
Xuzhou Medical College

Curated by ChEMBL
LigandPNGBDBM26289(N-(3-fluorophenyl)-2-{3-[(7-{3-[(2R)-2-(hydroxymet...)copy SMILEScopy InChI
Affinity DataKi:  1nM ΔG°:  -50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W24PubMed
TargetAurora kinase B(Homo sapiens (Human))
Xuzhou Medical College

Curated by ChEMBL
LigandPNGBDBM26290(N-(3-fluorophenyl)-2-{3-[(7-{3-[(2-hydroxyethyl)am...)copy SMILEScopy InChI
Affinity DataKi:  1nM ΔG°:  -50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W24PubMed
TargetAurora kinase B(Homo sapiens (Human))
Xuzhou Medical College

Curated by ChEMBL
LigandPNGBDBM26291(N-(3-fluorophenyl)-2-{3-[(7-{3-[(2-hydroxyethyl)(m...)copy SMILEScopy InChI
Affinity DataKi: <1nM ΔG°: <-50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W24PubMed
TargetAurora kinase B(Homo sapiens (Human))
Xuzhou Medical College

Curated by ChEMBL
LigandPNGBDBM26292(2-{3-[(7-{3-[ethyl(2-hydroxyethyl)amino]propoxy}-6...)copy SMILEScopy InChI
Affinity DataKi:  1nM ΔG°:  -50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W24PubMed
TargetAurora kinase B(Homo sapiens (Human))
Xuzhou Medical College

Curated by ChEMBL
LigandPNGBDBM26294(CHEMBL214848 | N-(2,3-difluorophenyl)-2-{3-[(7-{3-...)copy SMILEScopy InChI
Affinity DataKi: <1nM ΔG°: <-50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W24PubMed
TargetAurora kinase B(Homo sapiens (Human))
Xuzhou Medical College

Curated by ChEMBL
LigandPNGBDBM26296(CHEMBL216053 | N-(2,3-difluorophenyl)-2-{3-[(7-{3-...)copy SMILEScopy InChI
Affinity DataKi: <1nM ΔG°: <-50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W24PubMed
TargetAurora kinase B(Homo sapiens (Human))
Xuzhou Medical College

Curated by ChEMBL
LigandPNGBDBM26297(CHEMBL215322 | N-(2,3-difluorophenyl)-2-{3-[(7-{3-...)copy SMILEScopy InChI
Affinity DataKi: <1nM ΔG°: <-51.4kJ/moleT: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W24PubMed
TargetAurora kinase B(Homo sapiens (Human))
Xuzhou Medical College

Curated by ChEMBL
LigandPNGBDBM26298(N-(2,3-difluorophenyl)-2-{3-[(7-{3-[(2-hydroxyethy...)copy SMILEScopy InChI
Affinity DataKi: <1nM ΔG°: <-51.4kJ/moleT: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W24PubMed
TargetAurora kinase B(Homo sapiens (Human))
Xuzhou Medical College

Curated by ChEMBL
LigandPNGBDBM26299(N-(2,3-difluorophenyl)-2-{3-[(7-{3-[(2R)-2-(hydrox...)copy SMILEScopy InChI
Affinity DataKi: <1nM ΔG°: <-51.4kJ/moleT: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W24PubMed
TargetAurora kinase B(Homo sapiens (Human))
Xuzhou Medical College

Curated by ChEMBL
LigandPNGBDBM26300(2-{3-[(7-{3-[ethyl(2-hydroxyethyl)amino]propoxy}qu...)copy SMILEScopy InChI
Affinity DataKi: <1nM ΔG°: <-51.4kJ/moleT: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W24PubMed
TargetAurora kinase B(Homo sapiens (Human))
Xuzhou Medical College

Curated by ChEMBL
LigandPNGBDBM26301(N-(3-fluorophenyl)-2-{3-[(7-{3-[(2-hydroxyethyl)(p...)copy SMILEScopy InChI
Affinity DataKi: <1nM ΔG°: <-51.4kJ/moleT: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W24PubMed
TargetAurora kinase B(Homo sapiens (Human))
Xuzhou Medical College

Curated by ChEMBL
LigandPNGBDBM26302(N-(3-fluorophenyl)-2-{3-[(7-{3-[(2R)-2-(hydroxymet...)copy SMILEScopy InChI
Affinity DataKi: <1nM ΔG°: <-51.4kJ/moleT: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W24PubMed
TargetAurora kinase B(Homo sapiens (Human))
Xuzhou Medical College

Curated by ChEMBL
LigandPNGBDBM26303(4-aminopyrazole quinazoline, 3 | N-(2,3-difluoroph...)copy SMILEScopy InChI
Affinity DataKi: <1nM ΔG°: <-50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ64C7PubMed
TargetAurora kinase B(Homo sapiens (Human))
Xuzhou Medical College

Curated by ChEMBL
LigandPNGBDBM26304(4-aminopyrazole quinazoline, 4 | N-(2,3-difluoroph...)copy SMILEScopy InChI
Affinity DataKi: <1nM ΔG°: <-50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ64C7PubMed
TargetAurora kinase B(Homo sapiens (Human))
Xuzhou Medical College

Curated by ChEMBL
LigandPNGBDBM26305(4-aminopyrazole quinazoline, 5 | N-(3-fluorophenyl...)copy SMILEScopy InChI
Affinity DataKi:  1nM ΔG°:  -50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ64C7PubMed
TargetAurora kinase B(Homo sapiens (Human))
Xuzhou Medical College

Curated by ChEMBL
LigandPNGBDBM26306(2-{4-[(7-{3-[ethyl(2-hydroxyethyl)amino]propoxy}-6...)copy SMILEScopy InChI
Affinity DataKi:  1nM ΔG°:  -50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ64C7PubMed
TargetAurora kinase B(Homo sapiens (Human))
Xuzhou Medical College

Curated by ChEMBL
LigandPNGBDBM13534(CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...)copy SMILEScopy InChI
Affinity DataKi:  1.80nMAssay Description:Inhibition of Aurora-B by time dependent kinetic studyMore data for this Ligand-Target Pair
TargetAurora kinase B(Homo sapiens (Human))
Xuzhou Medical College

Curated by ChEMBL
LigandPNGBDBM13534(CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...)copy SMILEScopy InChI
Affinity DataKi:  1.80nMAssay Description:Competitive inhibition of Aurora B ATP binding siteMore data for this Ligand-Target Pair
TargetAurora kinase B(Homo sapiens (Human))
Xuzhou Medical College

Curated by ChEMBL
LigandPNGBDBM13534(CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...)copy SMILEScopy InChI
Affinity DataKi:  1.80nMAssay Description:Inhibition of Aurora B kinaseMore data for this Ligand-Target Pair
TargetAurora kinase B(Homo sapiens (Human))
Xuzhou Medical College

Curated by ChEMBL
LigandPNGBDBM26293(CHEMBL217804 | N-(3-fluorophenyl)-2-{3-[(7-{3-[(2-...)copy SMILEScopy InChI
Affinity DataKi:  2nM ΔG°:  -49.2kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W24PubMed
TargetAurora kinase B(Homo sapiens (Human))
Xuzhou Medical College

Curated by ChEMBL
LigandPNGBDBM26276(N-(2,3-difluorophenyl)-2-{3-[(7-{3-[4-(hydroxymeth...)copy SMILEScopy InChI
Affinity DataKi:  2nM ΔG°:  -49.2kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W24PubMed
TargetAurora kinase B(Homo sapiens (Human))
Xuzhou Medical College

Curated by ChEMBL
LigandPNGBDBM26274(CHEMBL216769 | N-(3-fluorophenyl)-2-{3-[(7-{3-[4-(...)copy SMILEScopy InChI
Affinity DataKi:  2nM ΔG°:  -49.2kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W24PubMed
TargetAurora kinase B(Homo sapiens (Human))
Xuzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50319623(4-(2,4-Dimethylthiazol-5-yl)-N-(3,4,5-trimethoxyph...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Inhibition of human recombinant Aurora B after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930T9DPubMed
TargetAurora kinase B(Homo sapiens (Human))
Xuzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50319622(CHEMBL1083152 | N,4-Dimethyl-5-(2-(3,4,5-trimethox...)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Inhibition of human recombinant Aurora B after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930T9DPubMed
TargetAurora kinase B(Homo sapiens (Human))
Xuzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50004205(MK-045 | MK-0457 | TOZASERTIB | US9249124, VX680 |...)copy SMILEScopy InChI
Affinity DataKi:  3.40nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0MHVPubMed
TargetAurora kinase B(Homo sapiens (Human))
Xuzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50319616(1-(4-(4-(4-(2-Amino-4-methylthiazol-5-yl)pyrimidin...)copy SMILEScopy InChI
Affinity DataKi:  3.80nMAssay Description:Inhibition of human recombinant Aurora B after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930T9DPubMed
TargetAurora kinase B(Homo sapiens (Human))
Xuzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50319620(CHEMBL1084715 | N-(4-(4-(2-(Ethylamino)-4-methylth...)copy SMILEScopy InChI
Affinity DataKi:  4nMAssay Description:Inhibition of human recombinant Aurora B after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930T9DPubMed
TargetAurora kinase B(Homo sapiens (Human))
Xuzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50442153(CHEMBL2441283)copy SMILEScopy InChI
Affinity DataKi:  5nMAssay Description:Inhibition of Aurora-B (unknown origin) using 5FAM-PKAtide as substrate after 120 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P61Z7PubMed
TargetAurora kinase B(Homo sapiens (Human))
Xuzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50319617(CHEMBL1084630 | N-Ethyl-4-methyl-5-(2-(4-morpholin...)copy SMILEScopy InChI
Affinity DataKi:  6nMAssay Description:Inhibition of human recombinant Aurora B after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930T9DPubMed
TargetAurora kinase B(Homo sapiens (Human))
Xuzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50319621(CHEMBL1086088 | N-Ethyl-4-methyl-5-(2-(3,4,5-trime...)copy SMILEScopy InChI
Affinity DataKi:  6nMAssay Description:Inhibition of human recombinant Aurora B after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930T9DPubMed
TargetAurora kinase B(Homo sapiens (Human))
Xuzhou Medical College

Curated by ChEMBL
LigandPNGBDBM26278(N-(3-chlorophenyl)-2-{3-[(7-{3-[4-(hydroxymethyl)p...)copy SMILEScopy InChI
Affinity DataKi:  8nM ΔG°:  -45.7kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W24PubMed
TargetAurora kinase B(Homo sapiens (Human))
Xuzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50277586(CHEMBL484951 | N-(4-(4-(5-methyl-1H-pyrazol-3-ylam...)copy SMILEScopy InChI
Affinity DataKi:  8nMAssay Description:Inhibition of Aurora-BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7944PubMed
TargetAurora kinase B(Homo sapiens (Human))
Xuzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50319619(4-(2,4-Dimethylthiazol-5-yl)-N-(4-morpholinophenyl...)copy SMILEScopy InChI
Affinity DataKi:  9nMAssay Description:Inhibition of human recombinant Aurora B after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930T9DPubMed
TargetAurora kinase B(Homo sapiens (Human))
Xuzhou Medical College

Curated by ChEMBL
LigandPNGBDBM26282(2-{3-[(7-{3-[4-(hydroxymethyl)piperidin-1-yl]propo...)copy SMILEScopy InChI
Affinity DataKi:  9nM ΔG°:  -45.5kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6W24PubMed
TargetAurora kinase B(Homo sapiens (Human))
Xuzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50277583(2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin...)copy SMILEScopy InChI
Affinity DataKi:  9.20nMAssay Description:Inhibition of human recombinant Aurora B after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930T9DPubMed
TargetAurora kinase B(Homo sapiens (Human))
Xuzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50319618(CHEMBL1084629 | N,4-Dimethyl-5-(2-(4-morpholinophe...)copy SMILEScopy InChI
Affinity DataKi:  9.40nMAssay Description:Inhibition of human recombinant Aurora B after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930T9DPubMed
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