Found 41 hits of Enzyme Inhibition Constant Data
Affinity DataIC50: 1nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails
Article
BindingDB Entry DOI: 10.7270/Q2NV9JP4PubMedDrugBank
MMDB
PDB
3D Structure (crystal)
BindingDB Entry DOI: 10.7270/Q2NV9JP4PubMedDrugBank
MMDB
PDB
3D Structure (crystal)
Affinity DataIC50: 1nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails
Article
BindingDB Entry DOI: 10.7270/Q2NV9JP4PubMedDrugBank
MMDB
PDB
3D Structure (crystal)
BindingDB Entry DOI: 10.7270/Q2NV9JP4PubMedDrugBank
MMDB
PDB
3D Structure (crystal)
Affinity DataIC50: 3nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi& Co., Ltd
Curated by ChEMBL
Shionogi& Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi& Co., Ltd
Curated by ChEMBL
Shionogi& Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails
Article
BindingDB Entry DOI: 10.7270/Q2NV9JP4PubMedDrugBank
MMDB
PDB
3D Structure (crystal)
BindingDB Entry DOI: 10.7270/Q2NV9JP4PubMedDrugBank
MMDB
PDB
3D Structure (crystal)
Affinity DataIC50: 10nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails
Article
BindingDB Entry DOI: 10.7270/Q2NV9JP4PubMedDrugBank
MMDB
PDB
3D Structure (crystal)
BindingDB Entry DOI: 10.7270/Q2NV9JP4PubMedDrugBank
MMDB
PDB
3D Structure (crystal)
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi& Co., Ltd
Curated by ChEMBL
Shionogi& Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi& Co., Ltd
Curated by ChEMBL
Shionogi& Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi& Co., Ltd
Curated by ChEMBL
Shionogi& Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 41nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi& Co., Ltd
Curated by ChEMBL
Shionogi& Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 41nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi& Co., Ltd
Curated by ChEMBL
Shionogi& Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 62nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi& Co., Ltd
Curated by ChEMBL
Shionogi& Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 73nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 74nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 79nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 86nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi& Co., Ltd
Curated by ChEMBL
Shionogi& Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 86nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 94nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 98nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi& Co., Ltd
Curated by ChEMBL
Shionogi& Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi& Co., Ltd
Curated by ChEMBL
Shionogi& Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi& Co., Ltd
Curated by ChEMBL
Shionogi& Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi& Co., Ltd
Curated by ChEMBL
Shionogi& Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi& Co., Ltd
Curated by ChEMBL
Shionogi& Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi& Co., Ltd
Curated by ChEMBL
Shionogi& Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi& Co., Ltd
Curated by ChEMBL
Shionogi& Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 240nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 650nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi& Co., Ltd
Curated by ChEMBL
Shionogi& Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 750nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi& Co., Ltd
Curated by ChEMBL
Shionogi& Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 760nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Aurora AMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Shionogi& Co., Ltd
Curated by ChEMBL
Shionogi& Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of INSRMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Shionogi& Co., Ltd
Curated by ChEMBL
Shionogi& Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PDGFRbetaMore data for this Ligand-Target Pair