Compile Data Set for Download or QSAR

Found 4 hits of Enzyme Inhibition Constant Data   

TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14169(4-Iodobenzo[b]thiophene-2-carboxamidine | APC-6860...)copy SMILEScopy InChI
Affinity DataKi:  210nM ΔG°:  -37.7kJ/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14170(APC-7377 | Benzo[b]thiophene-2-carboxamidine | [am...)copy SMILEScopy InChI
Affinity DataKi:  2.30E+3nM ΔG°:  -31.9kJ/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NG4NWCPubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM14171(APC-7538 | Thieno[2,3-b]pyridine-2-carboxamidine |...)copy SMILEScopy InChI
Affinity DataKi:  6.30E+4nM ΔG°:  -23.7kJ/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceutical

LigandPNGBDBM772(Benzamidine | CHEMBL79897 | [amino(phenyl)methylid...)copy SMILEScopy InChI
Affinity DataKi:  9.70E+4nM ΔG°:  -22.7kJ/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
* indicates data uncertainty>20%