Compile Data Set for Download or QSAR

Found 98 hits of Enzyme Inhibition Constant Data   

TargetVascular endothelial growth factor receptor 2(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6417(4-[(5-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed
TargetVascular endothelial growth factor receptor 2(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6421(N-(3-Chlorophenyl)-6-[5-[[3-(1H-1,2,4-triazol-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 67nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed
TargetVascular endothelial growth factor receptor 2(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6419(N-(3-Chlorophenyl)-6-[5-[[3-(3-pyridinyl)propyl]am...)copy SMILEScopy InChI
Affinity DataIC50: 76nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed
TargetVascular endothelial growth factor receptor 2(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6391((3-Chloro-phenyl)-{6-[5-(3-pyridin-4-yl-propylamin...)copy SMILEScopy InChI
Affinity DataIC50: 76nMpH: 8.0 T: 2°CAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed
TargetVascular endothelial growth factor receptor 2(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6416(3-[(5-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 84nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed
TargetVascular endothelial growth factor receptor 2(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6420(N-(3-Chlorophenyl)-6-[5-[[3-(1H-pyrazol-1-yl)propy...)copy SMILEScopy InChI
Affinity DataIC50: 94nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed
TargetVascular endothelial growth factor receptor 2(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6418(N-(3-chlorophenyl)-6-(5-{[2-(dimethylamino)ethyl]a...)copy SMILEScopy InChI
Affinity DataIC50: 105nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed
TargetVascular endothelial growth factor receptor 2(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6408((3-Chlorophenyl)-(6-{5-[3-(4-methyl-piperazin-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 123nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed
TargetVascular endothelial growth factor receptor 2(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6398(N-(3-chlorophenyl)-6-(5-{[3-(dimethylamino)propyl]...)copy SMILEScopy InChI
Affinity DataIC50: 135nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6421(N-(3-Chlorophenyl)-6-[5-[[3-(1H-1,2,4-triazol-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 153nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed
TargetVascular endothelial growth factor receptor 2(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6388(3-[(5-{6-[(3-fluorophenyl)amino]pyrazin-2-yl}pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 168nMpH: 8.0 T: 2°CAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed
TargetVascular endothelial growth factor receptor 2(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6409(N-(3-chlorophenyl)-6-(5-{[3-(morpholin-4-yl)propyl...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed
TargetVascular endothelial growth factor receptor 2(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6393((3,4-Dichloro-phenyl)-{6-[5-(3-pyridin-4-yl-propyl...)copy SMILEScopy InChI
Affinity DataIC50: 189nMpH: 8.0 T: 2°CAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Oryctolagus cuniculus (rabbit))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6421(N-(3-Chlorophenyl)-6-[5-[[3-(1H-1,2,4-triazol-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 196nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6416(3-[(5-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed
TargetVascular endothelial growth factor receptor 2(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6407(N-(3-Chlorophenyl)-6-[5-[[3-(1-piperazinyl)propyl]...)copy SMILEScopy InChI
Affinity DataIC50: 236nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed
TargetVascular endothelial growth factor receptor 2(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6423(3-[(5-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}-6-fl...)copy SMILEScopy InChI
Affinity DataIC50: 251nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed
TargetVascular endothelial growth factor receptor 2(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6412(N-(3-Chlorophenyl)-6-[5-[[4-(4-pyridinyl)butyl]ami...)copy SMILEScopy InChI
Affinity DataIC50: 266nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed
TargetVascular endothelial growth factor receptor 2(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6397(2-[(5-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 275nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6419(N-(3-Chlorophenyl)-6-[5-[[3-(3-pyridinyl)propyl]am...)copy SMILEScopy InChI
Affinity DataIC50: 293nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed
TargetVascular endothelial growth factor receptor 2(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6402(N-(5-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}pyridi...)copy SMILEScopy InChI
Affinity DataIC50: 303nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Oryctolagus cuniculus (rabbit))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6419(N-(3-Chlorophenyl)-6-[5-[[3-(3-pyridinyl)propyl]am...)copy SMILEScopy InChI
Affinity DataIC50: 318nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6420(N-(3-Chlorophenyl)-6-[5-[[3-(1H-pyrazol-1-yl)propy...)copy SMILEScopy InChI
Affinity DataIC50: 326nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed
TargetVascular endothelial growth factor receptor 2(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6401(N-(5-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}pyridi...)copy SMILEScopy InChI
Affinity DataIC50: 346nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6416(3-[(5-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 360nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed
TargetVascular endothelial growth factor receptor 2(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6411(N-(3-Chlorophenyl)-6-[5-[[(tetrahydro-2H-pyran-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 391nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed
TargetVascular endothelial growth factor receptor 2(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6410((3-Chlorophenyl)-{6-[5-(3-piperidin-1-yl-propylami...)copy SMILEScopy InChI
Affinity DataIC50: 399nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Oryctolagus cuniculus (rabbit))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6416(3-[(5-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 478nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed
TargetVascular endothelial growth factor receptor 2(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6415(4-[(5-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 568nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed
TargetVascular endothelial growth factor receptor 2(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6403(N-(5-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}pyridi...)copy SMILEScopy InChI
Affinity DataIC50: 593nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Oryctolagus cuniculus (rabbit))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6420(N-(3-Chlorophenyl)-6-[5-[[3-(1H-pyrazol-1-yl)propy...)copy SMILEScopy InChI
Affinity DataIC50: 606nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed
TargetVascular endothelial growth factor receptor 2(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6422(4-[(5-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 610nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6421(N-(3-Chlorophenyl)-6-[5-[[3-(1H-1,2,4-triazol-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 725nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed
TargetVascular endothelial growth factor receptor 2(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6389(3-[(5-{6-[(3-methoxyphenyl)amino]pyrazin-2-yl}pyri...)copy SMILEScopy InChI
Affinity DataIC50: 740nMpH: 8.0 T: 2°CAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6419(N-(3-Chlorophenyl)-6-[5-[[3-(3-pyridinyl)propyl]am...)copy SMILEScopy InChI
Affinity DataIC50: 876nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed
TargetVascular endothelial growth factor receptor 2(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6392((4-Chloro-phenyl)-{6-[5-(3-pyridin-4-yl-propylamin...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMpH: 8.0 T: 2°CAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed
TargetVascular endothelial growth factor receptor 2(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6390(3-[(5-{6-[(2-chlorophenyl)amino]pyrazin-2-yl}pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 1.01E+3nMpH: 8.0 T: 2°CAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed
TargetVascular endothelial growth factor receptor 2(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6394(3-({5-[6-(benzylamino)pyrazin-2-yl]pyridin-3-yl}am...)copy SMILEScopy InChI
Affinity DataIC50: 1.05E+3nMpH: 8.0 T: 2°CAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed
TargetVascular endothelial growth factor receptor 2(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6396(6-(5-aminopyridin-3-yl)-N-(3-chlorophenyl)pyrazin-...)copy SMILEScopy InChI
Affinity DataIC50: 1.16E+3nMpH: 8.0 T: 2°CAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6416(3-[(5-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 1.36E+3nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed
TargetVascular endothelial growth factor receptor 2(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6425(3-[(6-amino-5-{6-[(3-chlorophenyl)amino]pyrazin-2-...)copy SMILEScopy InChI
Affinity DataIC50: 1.36E+3nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6418(N-(3-chlorophenyl)-6-(5-{[2-(dimethylamino)ethyl]a...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6420(N-(3-Chlorophenyl)-6-[5-[[3-(1H-pyrazol-1-yl)propy...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed
TargetVascular endothelial growth factor receptor 2(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6413((3-Chloro-phenyl)-{6-[5-(3-phenyl-propylamino)-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 2.28E+3nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6417(4-[(5-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 2.36E+3nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed
TargetVascular endothelial growth factor receptor 2(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6400(5-[6-(3-Chloro-phenylamino)-pyrazin-2-yl]-N-(3-hyd...)copy SMILEScopy InChI
Affinity DataIC50: 2.38E+3nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6417(4-[(5-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+3nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6399(5-[6-(3-Chloro-phenylamino)-pyrazin-2-yl]-N-(2-(di...)copy SMILEScopy InChI
Affinity DataIC50: 3.69E+3nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed
TargetGlycogen synthase kinase-3 beta [7-25](Oryctolagus cuniculus (rabbit))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6417(4-[(5-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 4.02E+3nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed
TargetVascular endothelial growth factor receptor 2(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6399(5-[6-(3-Chloro-phenylamino)-pyrazin-2-yl]-N-(2-(di...)copy SMILEScopy InChI
Affinity DataIC50: 4.30E+3nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC5ZD5PubMed
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