Compile Data Set for Download or QSAR

Found 41 hits of Enzyme Inhibition Constant Data   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shionogi& Co., Ltd

Curated by ChEMBL
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shionogi& Co., Ltd

Curated by ChEMBL
LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shionogi& Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50360457(CHEMBL1934623)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9JP4PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shionogi& Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50360459(CHEMBL1934625)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9JP4PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shionogi& Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50360458(CHEMBL1934624)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9JP4PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi& Co., Ltd

Curated by ChEMBL
LigandPNGBDBM5445(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9JP4PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi& Co., Ltd

Curated by ChEMBL
LigandPNGBDBM5445(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9JP4PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shionogi& Co., Ltd

Curated by ChEMBL
LigandPNGBDBM5445(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shionogi& Co., Ltd

Curated by ChEMBL
LigandPNGBDBM5445(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi& Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50360457(CHEMBL1934623)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9JP4PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shionogi& Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50360456(CHEMBL1934622)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9JP4PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shionogi& Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50360466(CHEMBL1934632)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9JP4PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shionogi& Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50360461(CHEMBL1934628)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9JP4PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi& Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50360466(CHEMBL1934632)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9JP4PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi& Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50360458(CHEMBL1934624)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9JP4PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi& Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50360459(CHEMBL1934625)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9JP4PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shionogi& Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50360463(CHEMBL1933083)copy SMILEScopy InChI
Affinity DataIC50: 55nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9JP4PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi& Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50360453(CHEMBL1934626)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9JP4PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi& Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50360463(CHEMBL1933083)copy SMILEScopy InChI
Affinity DataIC50: 73nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9JP4PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shionogi& Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50360462(CHEMBL1934629)copy SMILEScopy InChI
Affinity DataIC50: 74nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9JP4PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shionogi& Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50360460(CHEMBL1934627)copy SMILEScopy InChI
Affinity DataIC50: 79nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9JP4PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shionogi& Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50360464(CHEMBL1934630)copy SMILEScopy InChI
Affinity DataIC50: 86nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9JP4PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi& Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50360467(CHEMBL1934633)copy SMILEScopy InChI
Affinity DataIC50: 86nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9JP4PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shionogi& Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50360465(CHEMBL1934631)copy SMILEScopy InChI
Affinity DataIC50: 94nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9JP4PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shionogi& Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50360467(CHEMBL1934633)copy SMILEScopy InChI
Affinity DataIC50: 98nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9JP4PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi& Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50360462(CHEMBL1934629)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9JP4PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi& Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50360465(CHEMBL1934631)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9JP4PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi& Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50360464(CHEMBL1934630)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9JP4PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi& Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50360460(CHEMBL1934627)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9JP4PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi& Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50360461(CHEMBL1934628)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9JP4PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shionogi& Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50360453(CHEMBL1934626)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9JP4PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi& Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50360456(CHEMBL1934622)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9JP4PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi& Co., Ltd

Curated by ChEMBL
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9JP4PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Shionogi& Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50360455(CHEMBL1934621)copy SMILEScopy InChI
Affinity DataIC50: 650nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9JP4PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi& Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50360455(CHEMBL1934621)copy SMILEScopy InChI
Affinity DataIC50: 750nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9JP4PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shionogi& Co., Ltd

Curated by ChEMBL
LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)copy SMILEScopy InChI
Affinity DataIC50: 760nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9JP4PubMed
TargetAurora kinase A(Homo sapiens (Human))
Shionogi& Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50360453(CHEMBL1934626)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Aurora AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9JP4PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Shionogi& Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50360453(CHEMBL1934626)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9JP4PubMed
TargetInsulin receptor(Homo sapiens (Human))
Shionogi& Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50360453(CHEMBL1934626)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of INSRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9JP4PubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Shionogi& Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50360453(CHEMBL1934626)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9JP4PubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Shionogi& Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50360453(CHEMBL1934626)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9JP4PubMed
* indicates data uncertainty>20%