Compile Data Set for Download or QSAR

Found 11 hits of Enzyme Inhibition Constant Data   

TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM25270([(6E,11E)-2,6,12,16-tetramethyl-9-phosphonoheptade...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant GGDPS (unknown origin) assessed as decrease in radiolabeld GGPP level using FPP and [14C]IPP as substrate treated with enzy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TD9ZWVPubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50013157(CHEMBL3262352)copy SMILEScopy InChI
Affinity DataIC50: 380nMAssay Description:Inhibition of recombinant GGDPS (unknown origin) assessed as decrease in radiolabeld GGPP level using FPP and [14C]IPP as substrate treated with enzy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TD9ZWVPubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50013156(CHEMBL3262351)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of recombinant GGDPS (unknown origin) assessed as decrease in radiolabeld GGPP level using FPP and [14C]IPP as substrate treated with enzy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TD9ZWVPubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50013159(CHEMBL3262354)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of recombinant GGDPS (unknown origin) assessed as decrease in radiolabeld GGPP level using FPP and [14C]IPP as substrate treated with enzy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TD9ZWVPubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50013156(CHEMBL3262351)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of recombinant GGDPS (unknown origin) assessed as decrease in radiolabeld GGPP level using FPP and [14C]IPP as substrate treated with enzy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TD9ZWVPubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50013158(CHEMBL3262353)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of recombinant GGDPS (unknown origin) assessed as decrease in radiolabeld GGPP level using FPP and [14C]IPP as substrate treated with enzy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TD9ZWVPubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50013158(CHEMBL3262353)copy SMILEScopy InChI
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of recombinant FDPS (unknown origin) assessed as decrease in radiolabeld GGPP level using GPP and [14C]IPP as substrate treated with enzym...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TD9ZWVPubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50013159(CHEMBL3262354)copy SMILEScopy InChI
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibition of recombinant FDPS (unknown origin) assessed as decrease in radiolabeld GGPP level using GPP and [14C]IPP as substrate treated with enzym...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TD9ZWVPubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50013156(CHEMBL3262351)copy SMILEScopy InChI
Affinity DataIC50: 5.70E+4nMAssay Description:Inhibition of recombinant FDPS (unknown origin) assessed as decrease in radiolabeld GGPP level using GPP and [14C]IPP as substrate treated with enzym...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TD9ZWVPubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50013156(CHEMBL3262351)copy SMILEScopy InChI
Affinity DataIC50: 5.70E+4nMAssay Description:Inhibition of recombinant FDPS (unknown origin) assessed as decrease in radiolabeld GGPP level using GPP and [14C]IPP as substrate treated with enzym...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TD9ZWVPubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50013157(CHEMBL3262352)copy SMILEScopy InChI
Affinity DataIC50: 7.90E+4nMAssay Description:Inhibition of recombinant FDPS (unknown origin) assessed as decrease in radiolabeld GGPP level using GPP and [14C]IPP as substrate treated with enzym...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TD9ZWVPubMed
* indicates data uncertainty>20%