Compile Data Set for Download or QSAR

Found 25 hits of Enzyme Inhibition Constant Data   

TargetRhomboid protease GlpG(Haemophilus influenzae (g-Proteobacteria))
Technische Universität München

LigandPNGBDBM50199883(3,4‐Dichloroisocoumarin (2) | 3,4-Dichloro-i...)copy SMILEScopy InChI
Affinity DataIC50: 660nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668BZ8PubMed
TargetRhomboid domain-containing protein(Thermotoga maritima (Thermotogales))
Technische Universität München

LigandPNGBDBM50199883(3,4‐Dichloroisocoumarin (2) | 3,4-Dichloro-i...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668BZ8PubMed
TargetRhomboid domain-containing protein(Aquifex aeolicus (Aquificales))
Technische Universität München

LigandPNGBDBM50199883(3,4‐Dichloroisocoumarin (2) | 3,4-Dichloro-i...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668BZ8PubMed
TargetRhomboid domain-containing protein(Aquifex aeolicus (Aquificales))
Technische Universität München

LigandPNGBDBM165194(4‐Chloro‐7‐nitro‐3‐[...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668BZ8PubMed
TargetRhomboid protease GluP [F193S,L370F,L379S,R499W](Bacillus subtilis (Firmicutes))
Technische Universität München

LigandPNGBDBM50199883(3,4‐Dichloroisocoumarin (2) | 3,4-Dichloro-i...)copy SMILEScopy InChI
Affinity DataIC50: 4.10E+3nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668BZ8PubMed
TargetRhomboid protease GlpG(Haemophilus influenzae (g-Proteobacteria))
Technische Universität München

LigandPNGBDBM165194(4‐Chloro‐7‐nitro‐3‐[...)copy SMILEScopy InChI
Affinity DataIC50: 4.60E+3nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668BZ8PubMed
TargetAN1-type domain-containing protein(Archaeoglobus fulgidus (AfROM))
Technische Universität München

LigandPNGBDBM165195((4S)‐4‐(pent‐4‐yn‐1&...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668BZ8PubMed
TargetAN1-type domain-containing protein(Archaeoglobus fulgidus (AfROM))
Technische Universität München

LigandPNGBDBM50199883(3,4‐Dichloroisocoumarin (2) | 3,4-Dichloro-i...)copy SMILEScopy InChI
Affinity DataIC50: 8.10E+3nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668BZ8PubMed
TargetRhomboid protease AarA(Providencia stuartii (Enterobacteria))
Technische Universität München

LigandPNGBDBM165194(4‐Chloro‐7‐nitro‐3‐[...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668BZ8PubMed
TargetRhomboid protease AarA(Providencia stuartii (Enterobacteria))
Technische Universität München

LigandPNGBDBM50199883(3,4‐Dichloroisocoumarin (2) | 3,4-Dichloro-i...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668BZ8PubMed
TargetRhomboid domain-containing protein(Pyrococcus horikoshii (Euryarchaeotes))
Technische Universität München

LigandPNGBDBM50199883(3,4‐Dichloroisocoumarin (2) | 3,4-Dichloro-i...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+4nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668BZ8PubMed
TargetRhomboid protease GlpG(Escherichia coli (Enterobacteria))
Technische Universität München

LigandPNGBDBM50199883(3,4‐Dichloroisocoumarin (2) | 3,4-Dichloro-i...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+4nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668BZ8PubMed
TargetRhomboid-related protein 3(Mus musculus (Mouse))
Technische Universität München

LigandPNGBDBM165194(4‐Chloro‐7‐nitro‐3‐[...)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+4nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668BZ8PubMed
TargetRhomboid domain-containing protein(Pyrococcus horikoshii (Euryarchaeotes))
Technische Universität München

LigandPNGBDBM165194(4‐Chloro‐7‐nitro‐3‐[...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668BZ8PubMed
TargetRhomboid protease GluP [F193S,L370F,L379S,R499W](Bacillus subtilis (Firmicutes))
Technische Universität München

LigandPNGBDBM165194(4‐Chloro‐7‐nitro‐3‐[...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668BZ8PubMed
TargetRhomboid domain-containing protein(Thermotoga maritima (Thermotogales))
Technische Universität München

LigandPNGBDBM165196((4S)‐4‐(pent‐4‐yn‐1&...)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+4nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668BZ8PubMed
TargetGlpG protein(Vibrio cholerae (g-Proteobacteria))
Technische Universität München

LigandPNGBDBM50199883(3,4‐Dichloroisocoumarin (2) | 3,4-Dichloro-i...)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+4nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668BZ8PubMed
TargetRhomboid-related protein 1(Mus musculus (Mouse))
Technische Universität München

LigandPNGBDBM50199883(3,4‐Dichloroisocoumarin (2) | 3,4-Dichloro-i...)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+4nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668BZ8PubMed
TargetRhomboid domain-containing protein(Thermotoga maritima (Thermotogales))
Technische Universität München

LigandPNGBDBM165194(4‐Chloro‐7‐nitro‐3‐[...)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+4nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668BZ8PubMed
TargetRhomboid-related protein 1(Mus musculus (Mouse))
Technische Universität München

LigandPNGBDBM165194(4‐Chloro‐7‐nitro‐3‐[...)copy SMILEScopy InChI
Affinity DataIC50: 3.90E+4nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668BZ8PubMed
TargetRhomboid protease GlpG(Escherichia coli (Enterobacteria))
Technische Universität München

LigandPNGBDBM165197((4S)‐3‐butyl‐4‐(pent‐...)copy SMILEScopy InChI
Affinity DataIC50: 4.40E+4nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668BZ8PubMed
TargetRhomboid domain-containing protein(Thermotoga maritima (Thermotogales))
Technische Universität München

LigandPNGBDBM165197((4S)‐3‐butyl‐4‐(pent‐...)copy SMILEScopy InChI
Affinity DataIC50: 4.80E+4nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668BZ8PubMed
TargetRhomboid protease GlpG(Haemophilus influenzae (g-Proteobacteria))
Technische Universität München

LigandPNGBDBM165195((4S)‐4‐(pent‐4‐yn‐1&...)copy SMILEScopy InChI
Affinity DataIC50: 6.50E+4nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668BZ8PubMed
TargetRhomboid-related protein 3(Mus musculus (Mouse))
Technische Universität München

LigandPNGBDBM50199883(3,4‐Dichloroisocoumarin (2) | 3,4-Dichloro-i...)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+4nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668BZ8PubMed
TargetGlpG protein(Vibrio cholerae (g-Proteobacteria))
Technische Universität München

LigandPNGBDBM165194(4‐Chloro‐7‐nitro‐3‐[...)copy SMILEScopy InChI
Affinity DataIC50: 7.60E+4nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668BZ8PubMed
* indicates data uncertainty>20%