Compile Data Set for Download or QSAR

Found 51 hits of Enzyme Inhibition Constant Data   

TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine

Curated by ChEMBL
LigandPNGBDBM50196623(CHEMBL3976182 | US10167270, Example 00164 | US1050...)copy SMILEScopy InChI
Affinity DataIC50: 5.20nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8VV6PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine

Curated by ChEMBL
LigandPNGBDBM50196521(CHEMBL3939100 | US10167270, Example 00162 | US1050...)copy SMILEScopy InChI
Affinity DataIC50: 6.5nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8VV6PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine

Curated by ChEMBL
LigandPNGBDBM50196623(CHEMBL3976182 | US10167270, Example 00164 | US1050...)copy SMILEScopy InChI
Affinity DataIC50: 6.60nMpH: 7.0Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 7 preincubated for 5 mins followed by addition o...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8VV6PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine

Curated by ChEMBL
LigandPNGBDBM50196519(CHEMBL3930102 | US10167270, Example 00163 | US1050...)copy SMILEScopy InChI
Affinity DataIC50: 8.20nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8VV6PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine

Curated by ChEMBL
LigandPNGBDBM50196528(CHEMBL3923120 | US10167270, Example 00161 | US1050...)copy SMILEScopy InChI
Affinity DataIC50: 8.30nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8VV6PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine

Curated by ChEMBL
LigandPNGBDBM50196514(CHEMBL3950881 | US10167270, Example 00159)copy SMILEScopy InChI
Affinity DataIC50: 8.70nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8VV6PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine

Curated by ChEMBL
LigandPNGBDBM50196623(CHEMBL3976182 | US10167270, Example 00164 | US1050...)copy SMILEScopy InChI
Affinity DataIC50: 8.90nMpH: 5.0Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5 preincubated for 5 mins followed by addition o...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8VV6PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine

Curated by ChEMBL
LigandPNGBDBM50196521(CHEMBL3939100 | US10167270, Example 00162 | US1050...)copy SMILEScopy InChI
Affinity DataIC50: 9.40nMpH: 7.0Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 7 preincubated for 5 mins followed by addition o...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8VV6PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine

Curated by ChEMBL
LigandPNGBDBM50196622(CHEMBL3923147 | US10167270, Example 00160 | US1050...)copy SMILEScopy InChI
Affinity DataIC50: 9.90nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8VV6PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine

Curated by ChEMBL
LigandPNGBDBM50196521(CHEMBL3939100 | US10167270, Example 00162 | US1050...)copy SMILEScopy InChI
Affinity DataIC50: 11nMpH: 5.0Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5 preincubated for 5 mins followed by addition o...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8VV6PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine

Curated by ChEMBL
LigandPNGBDBM50196634(CHEMBL3976949 | US10167270, Compound 11b)copy SMILEScopy InChI
Affinity DataIC50: 13nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8VV6PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine

Curated by ChEMBL
LigandPNGBDBM50196528(CHEMBL3923120 | US10167270, Example 00161 | US1050...)copy SMILEScopy InChI
Affinity DataIC50: 13nMpH: 7.0Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 7 preincubated for 5 mins followed by addition o...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8VV6PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine

Curated by ChEMBL
LigandPNGBDBM50196519(CHEMBL3930102 | US10167270, Example 00163 | US1050...)copy SMILEScopy InChI
Affinity DataIC50: 13nMpH: 7.0Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 7 preincubated for 5 mins followed by addition o...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8VV6PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine

Curated by ChEMBL
LigandPNGBDBM50196519(CHEMBL3930102 | US10167270, Example 00163 | US1050...)copy SMILEScopy InChI
Affinity DataIC50: 14nMpH: 5.0Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5 preincubated for 5 mins followed by addition o...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8VV6PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine

Curated by ChEMBL
LigandPNGBDBM50196514(CHEMBL3950881 | US10167270, Example 00159)copy SMILEScopy InChI
Affinity DataIC50: 17nMpH: 7.0Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 7 preincubated for 5 mins followed by addition o...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8VV6PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine

Curated by ChEMBL
LigandPNGBDBM50196622(CHEMBL3923147 | US10167270, Example 00160 | US1050...)copy SMILEScopy InChI
Affinity DataIC50: 19nMpH: 7.0Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 7 preincubated for 5 mins followed by addition o...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8VV6PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine

Curated by ChEMBL
LigandPNGBDBM50196534(CHEMBL3956777)copy SMILEScopy InChI
Affinity DataIC50: 20nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8VV6PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine

Curated by ChEMBL
LigandPNGBDBM50196610(CHEMBL3956552 | US10167270, Compound 11h)copy SMILEScopy InChI
Affinity DataIC50: 21nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8VV6PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine

Curated by ChEMBL
LigandPNGBDBM50196514(CHEMBL3950881 | US10167270, Example 00159)copy SMILEScopy InChI
Affinity DataIC50: 22nMpH: 5.0Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5 preincubated for 5 mins followed by addition o...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8VV6PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine

Curated by ChEMBL
LigandPNGBDBM50196528(CHEMBL3923120 | US10167270, Example 00161 | US1050...)copy SMILEScopy InChI
Affinity DataIC50: 26nMpH: 5.0Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5 preincubated for 5 mins followed by addition o...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8VV6PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine

Curated by ChEMBL
LigandPNGBDBM50196531(CHEMBL3964444 | US10167270, Compound 7a)copy SMILEScopy InChI
Affinity DataIC50: 27nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8VV6PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine

Curated by ChEMBL
LigandPNGBDBM50196524(CHEMBL3968646 | US10167270, Compound 11c)copy SMILEScopy InChI
Affinity DataIC50: 29nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8VV6PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine

Curated by ChEMBL
LigandPNGBDBM50196622(CHEMBL3923147 | US10167270, Example 00160 | US1050...)copy SMILEScopy InChI
Affinity DataIC50: 30nMpH: 5.0Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5 preincubated for 5 mins followed by addition o...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8VV6PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine

Curated by ChEMBL
LigandPNGBDBM50196526(CHEMBL3941104)copy SMILEScopy InChI
Affinity DataIC50: 35nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8VV6PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine

Curated by ChEMBL
LigandPNGBDBM50196530(CHEMBL3974789 | US10167270, Compound 7b)copy SMILEScopy InChI
Affinity DataIC50: 42nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8VV6PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine

Curated by ChEMBL
LigandPNGBDBM50196535(CHEMBL3948124 | US10167270, Compound 6a)copy SMILEScopy InChI
Affinity DataIC50: 56nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8VV6PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine

Curated by ChEMBL
LigandPNGBDBM50033286(CHEMBL544818 | Phenethyl-(2-pyridin-3-yl-quinazoli...)copy SMILEScopy InChI
Affinity DataIC50: 97nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8VV6PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine

Curated by ChEMBL
LigandPNGBDBM50196536(CHEMBL3906252 | US10167270, Compound 11a)copy SMILEScopy InChI
Affinity DataIC50: 122nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8VV6PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine

Curated by ChEMBL
LigandPNGBDBM50196627(CHEMBL3929224 | US10167270, Compound 6b)copy SMILEScopy InChI
Affinity DataIC50: 126nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8VV6PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine

Curated by ChEMBL
LigandPNGBDBM50196522(CHEMBL3957610 | US10167270, Compound 11e)copy SMILEScopy InChI
Affinity DataIC50: 168nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8VV6PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine

Curated by ChEMBL
LigandPNGBDBM50196518(CHEMBL3920301 | US10167270, Compound 4)copy SMILEScopy InChI
Affinity DataIC50: 177nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8VV6PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine

Curated by ChEMBL
LigandPNGBDBM50196517(CHEMBL3980248 | US10167270, Compound 6f)copy SMILEScopy InChI
Affinity DataIC50: 234nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8VV6PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine

Curated by ChEMBL
LigandPNGBDBM50196633(CHEMBL3965871 | US10167270, Compound 6d)copy SMILEScopy InChI
Affinity DataIC50: 251nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8VV6PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine

Curated by ChEMBL
LigandPNGBDBM50196635(CHEMBL3970989 | US10167270, Compound 7g)copy SMILEScopy InChI
Affinity DataIC50: 282nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8VV6PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine

Curated by ChEMBL
LigandPNGBDBM50196624(CHEMBL3963682 | US10167270, Compound 7h)copy SMILEScopy InChI
Affinity DataIC50: 405nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8VV6PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine

Curated by ChEMBL
LigandPNGBDBM50196533(CHEMBL3894465 | US10167270, Compound 6e)copy SMILEScopy InChI
Affinity DataIC50: 431nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8VV6PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine

Curated by ChEMBL
LigandPNGBDBM50196516(CHEMBL3968279 | US10167270, Compound 7c)copy SMILEScopy InChI
Affinity DataIC50: 720nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8VV6PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine

Curated by ChEMBL
LigandPNGBDBM50196527(CHEMBL3970658 | US10167270, Compound 9e)copy SMILEScopy InChI
Affinity DataIC50: 821nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8VV6PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine

Curated by ChEMBL
LigandPNGBDBM50196631(CHEMBL3898722 | US10167270, Compound 7i)copy SMILEScopy InChI
Affinity DataIC50: 857nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8VV6PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine

Curated by ChEMBL
LigandPNGBDBM50196628(CHEMBL3932095 | US10167270, Compound 9d)copy SMILEScopy InChI
Affinity DataIC50: 872nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8VV6PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine

Curated by ChEMBL
LigandPNGBDBM50196632(CHEMBL3921895 | US10167270, Compound 6h)copy SMILEScopy InChI
Affinity DataIC50: 891nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8VV6PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine

Curated by ChEMBL
LigandPNGBDBM50196525(CHEMBL3908863 | US10167270, Compound 7f)copy SMILEScopy InChI
Affinity DataIC50: 926nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8VV6PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine

Curated by ChEMBL
LigandPNGBDBM50196626(CHEMBL3972062 | US10167270, Compound 8e)copy SMILEScopy InChI
Affinity DataIC50: 1.28E+3nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8VV6PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine

Curated by ChEMBL
LigandPNGBDBM50196515(CHEMBL3913022 | US10167270, Compound 8f)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8VV6PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine

Curated by ChEMBL
LigandPNGBDBM50196630(CHEMBL3942452 | US10167270, Compound 8d)copy SMILEScopy InChI
Affinity DataIC50: 1.53E+3nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8VV6PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine

Curated by ChEMBL
LigandPNGBDBM50196520(CHEMBL3944808 | US10167270, Compound 7d)copy SMILEScopy InChI
Affinity DataIC50: 2.84E+3nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8VV6PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine

Curated by ChEMBL
LigandPNGBDBM50196523(CHEMBL3914158 | US10167270, Compound 8g)copy SMILEScopy InChI
Affinity DataIC50: 4.29E+3nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8VV6PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine

Curated by ChEMBL
LigandPNGBDBM50033284(Benzyl-(2-pyridin-3-yl-quinazolin-4-yl)-amine | CH...)copy SMILEScopy InChI
Affinity DataIC50: 5.77E+3nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8VV6PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine

Curated by ChEMBL
LigandPNGBDBM50196529(CHEMBL3979185 | US10167270, Compound 7e)copy SMILEScopy InChI
Affinity DataIC50: 2.81E+4nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8VV6PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine

Curated by ChEMBL
LigandPNGBDBM50196532(CHEMBL3912910 | US10167270, Compound 6j)copy SMILEScopy InChI
Affinity DataIC50: 3.32E+4nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8VV6PubMed
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