Found 51 hits of Enzyme Inhibition Constant Data
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Affinity DataIC50: 5.20nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Affinity DataIC50: 6.5nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Affinity DataIC50: 6.60nMpH: 7.0Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 7 preincubated for 5 mins followed by addition o...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Affinity DataIC50: 8.20nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Affinity DataIC50: 8.30nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Affinity DataIC50: 8.70nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Affinity DataIC50: 8.90nMpH: 5.0Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5 preincubated for 5 mins followed by addition o...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Affinity DataIC50: 9.40nMpH: 7.0Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 7 preincubated for 5 mins followed by addition o...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Affinity DataIC50: 9.90nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Affinity DataIC50: 11nMpH: 5.0Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5 preincubated for 5 mins followed by addition o...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Affinity DataIC50: 13nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Affinity DataIC50: 13nMpH: 7.0Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 7 preincubated for 5 mins followed by addition o...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Affinity DataIC50: 13nMpH: 7.0Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 7 preincubated for 5 mins followed by addition o...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Affinity DataIC50: 14nMpH: 5.0Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5 preincubated for 5 mins followed by addition o...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Affinity DataIC50: 17nMpH: 7.0Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 7 preincubated for 5 mins followed by addition o...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Affinity DataIC50: 19nMpH: 7.0Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 7 preincubated for 5 mins followed by addition o...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Affinity DataIC50: 20nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Affinity DataIC50: 21nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Affinity DataIC50: 22nMpH: 5.0Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5 preincubated for 5 mins followed by addition o...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Affinity DataIC50: 26nMpH: 5.0Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5 preincubated for 5 mins followed by addition o...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Affinity DataIC50: 27nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Affinity DataIC50: 29nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Affinity DataIC50: 30nMpH: 5.0Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5 preincubated for 5 mins followed by addition o...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Affinity DataIC50: 35nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Affinity DataIC50: 42nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Affinity DataIC50: 56nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Affinity DataIC50: 97nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Affinity DataIC50: 122nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Affinity DataIC50: 126nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Affinity DataIC50: 168nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Affinity DataIC50: 177nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Affinity DataIC50: 234nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Affinity DataIC50: 251nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Affinity DataIC50: 282nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Affinity DataIC50: 405nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Affinity DataIC50: 431nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Affinity DataIC50: 720nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Affinity DataIC50: 821nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Affinity DataIC50: 857nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Affinity DataIC50: 872nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Affinity DataIC50: 891nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Affinity DataIC50: 926nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.28E+3nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.53E+3nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Affinity DataIC50: 2.84E+3nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Affinity DataIC50: 4.29E+3nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Affinity DataIC50: 5.77E+3nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Affinity DataIC50: 2.81E+4nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Northwestern University Feinberg School of Medicine
Curated by ChEMBL
Affinity DataIC50: 3.32E+4nMpH: 5.9Assay Description:Inhibition of synthetic recombinant wild type GCase enzyme velaglucerase alfa (unknown origin) at pH 5.9 preincubated for 5 mins followed by addition...More data for this Ligand-Target Pair
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