Found 224 hits of Enzyme Inhibition Constant Data
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human EAAT1 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 3.60nMAssay Description:Inhibition of human EAAT1 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 5.10nMAssay Description:Inhibition of human EAAT1 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 5.10nMAssay Description:Inhibition of human EAAT1 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 6.10nMAssay Description:Inhibition of human EAAT1 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 6.20nMAssay Description:Inhibition of human EAAT1 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of human EAAT1 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of human EAAT1 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of human EAAT1 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of human EAAT1 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of human EAAT1 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of human EAAT1 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibition of human EAAT1 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibition of human EAAT1 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 4(Rattus norvegicus)
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of rat EAAT4 expressed in tsA201 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 4(Rattus norvegicus)
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of rat EAAT4 expressed in tsA201 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 4(Rattus norvegicus)
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Inhibition of rat EAAT4 expressed in tsA201 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 4(Rattus norvegicus)
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of rat EAAT4 expressed in tsA201 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:Inhibition of human EAAT3 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:Inhibition of human EAAT3 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 4(Rattus norvegicus)
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 71nMAssay Description:Inhibition of rat EAAT4 expressed in tsA201 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 71nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
3D Structure (crystal)TargetExcitatory amino acid transporter 4(Rattus norvegicus)
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 71nMAssay Description:Inhibition of rat EAAT4 expressed in tsA201 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 71nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 4(Rattus norvegicus)
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 79nMAssay Description:Inhibition of rat EAAT4 expressed in tsA201 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 4(Rattus norvegicus)
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of rat EAAT4 expressed in tsA201 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 84nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 85nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 93nMAssay Description:Inhibition of human EAAT3 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 94nMAssay Description:Inhibition of human EAAT3 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 105nMAssay Description:Inhibition of human EAAT3 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 107nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of human EAAT3 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 117nMAssay Description:Inhibition of human EAAT3 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of human EAAT3 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 129nMAssay Description:Inhibition of human EAAT3 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of human EAAT3 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 4(Rattus norvegicus)
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 138nMAssay Description:Inhibition of rat EAAT4 expressed in tsA201 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 4(Rattus norvegicus)
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of rat EAAT4 expressed in tsA201 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
