Compile Data Set for Download or QSAR

Found 52 hits of Enzyme Inhibition Constant Data   

TargetAdenosine deaminase(Plasmodium falciparum)
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM50519495(CHEMBL34023)copy SMILEScopy InChI
Affinity DataKi:  0.00700nMAssay Description:Inhibition of Plasmodium falciparum ADA assessed as reduction in formation of ammonia using adenosine as substrate incubated for 15 mins by spectroph...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1571NPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM50293087(2-amino-7-(((3R,4R)-3-hydroxy-4-(hydroxymethyl)pyr...)copy SMILEScopy InChI
Affinity DataKi:  0.00700nMAssay Description:Inhibition of human His-tagged PNP assessed as equilibrium dissociation constant by measuring reduction in uric acid formation by spectrophotometric ...More data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM22109(7-{[(3R,4R)-3-hydroxy-4-(hydroxymethyl)pyrrolidin-...)copy SMILEScopy InChI
Affinity DataKi:  0.0160nMAssay Description:Inhibition of human His-tagged PNP assessed as equilibrium dissociation constant by measuring reduction in uric acid formation by spectrophotometric ...More data for this Ligand-Target Pair
TargetAdenosine deaminase(Homo sapiens (Human))
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM22925((8R)-3-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxol...)copy SMILEScopy InChI
Affinity DataKi:  0.0260nMAssay Description:Inhibition of human erythrocytes ADA assessed as equilibrium dissociation constant by measuring reduction in formation of inosine using adenosine as ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1571NPubMedDrugBank
TargetAdenosine deaminase(Plasmodium falciparum)
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM22925((8R)-3-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxol...)copy SMILEScopy InChI
Affinity DataKi:  0.0380nMAssay Description:Inhibition of Plasmodium falciparum N-terminal thrombin cleavable His6-tagged ADA expressed in Escherichia coli BL21 assessed as equilibrium dissocia...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1571NPubMed
TargetAdenosine deaminase(Plasmodium falciparum)
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM50367032(COFORMYCIN)copy SMILEScopy InChI
Affinity DataKi:  0.0800nMAssay Description:Inhibition of Plasmodium falciparum N-terminal thrombin cleavable His6-tagged ADA expressed in Escherichia coli BL21 assessed as equilibrium dissocia...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1571NPubMed
TargetAdenosine deaminase(Homo sapiens (Human))
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM50367032(COFORMYCIN)copy SMILEScopy InChI
Affinity DataKi:  0.110nMAssay Description:Inhibition of human erythrocytes ADA assessed as equilibrium dissociation constant by measuring reduction in formation of inosine using adenosine as ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1571NPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM50293087(2-amino-7-(((3R,4R)-3-hydroxy-4-(hydroxymethyl)pyr...)copy SMILEScopy InChI
Affinity DataKi:  0.160nMAssay Description:Inhibition of human His-tagged PNP assessed as inhibitor constant for enzyme-inhibitor complex formation by measuring reduction in uric acid formatio...More data for this Ligand-Target Pair
TargetAdenosine deaminase(Plasmodium falciparum)
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM50367032(COFORMYCIN)copy SMILEScopy InChI
Affinity DataKi:  0.25nMAssay Description:Inhibition of Plasmodium falciparum ADA assessed as reduction in formation of ammonia using adenosine as substrate incubated for 15 mins by spectroph...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1571NPubMed
TargetAdenosine deaminase(Plasmodium falciparum)
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM50519494(CHEMBL1234234)copy SMILEScopy InChI
Affinity DataKi:  0.430nMAssay Description:Inhibition of Plasmodium falciparum N-terminal thrombin cleavable His6-tagged ADA expressed in Escherichia coli BL21 assessed as equilibrium dissocia...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1571NPubMed
TargetAdenosine deaminase(Homo sapiens (Human))
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM22925((8R)-3-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxol...)copy SMILEScopy InChI
Affinity DataKi:  0.5nMAssay Description:Inhibition of human erythrocytes ADA assessed as reduction in formation of inosine using adenosine as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1571NPubMedDrugBank
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM22109(7-{[(3R,4R)-3-hydroxy-4-(hydroxymethyl)pyrrolidin-...)copy SMILEScopy InChI
Affinity DataKi:  0.5nMAssay Description:Inhibition of Plasmodium falciparum His-tagged PNP expressed in Escherichia coli assessed as inhibitor constant for enzyme-inhibitor complex formatio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1571NPubMed
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM50195587(1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-...)copy SMILEScopy InChI
Affinity DataKi:  0.600nMAssay Description:Inhibition of Plasmodium falciparum His-tagged PNP assessed as inhibitor constant for enzyme-inhibitor-substrate complex formationMore data for this Ligand-Target Pair
TargetAdenosine deaminase(Plasmodium falciparum)
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM50367032(COFORMYCIN)copy SMILEScopy InChI
Affinity DataKi:  0.680nMAssay Description:Inhibition of Plasmodium falciparum N-terminal thrombin cleavable His6-tagged ADA expressed in Escherichia coli BL21 assessed as reduction in formati...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1571NPubMed
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM50247158(7-(((3S,4S)-3-hydroxy-4-(hydroxymethyl)pyrrolidin-...)copy SMILEScopy InChI
Affinity DataKi:  0.680nMAssay Description:Inhibition of Plasmodium falciparum His-tagged PNP assessed as inhibitor constant for enzyme-inhibitor-substrate complex formationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1571NPubMed
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM50293087(2-amino-7-(((3R,4R)-3-hydroxy-4-(hydroxymethyl)pyr...)copy SMILEScopy InChI
Affinity DataKi:  0.890nMAssay Description:Inhibition of Plasmodium falciparum His-tagged PNP expressed in Escherichia coli assessed as inhibitor constant for enzyme-inhibitor complex formatio...More data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM50293086((1S)-1,4-dideoxy-1,4-imino-1-(9-deazaguanin-9-yl)-...)copy SMILEScopy InChI
Affinity DataKi:  0.900nMAssay Description:Inhibition of Plasmodium falciparum His-tagged PNP assessed as inhibitor constant for enzyme-inhibitor-substrate complex formationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1571NPubMed
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM50293088(7-((2R,3R,4S,5S)-3,4-dihydroxy-5-(hydroxymethyl)py...)copy SMILEScopy InChI
Affinity DataKi:  0.900nMAssay Description:Inhibition of Plasmodium falciparum His-tagged PNP assessed as inhibitor constant for enzyme-inhibitor-substrate complex formationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1571NPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM22109(7-{[(3R,4R)-3-hydroxy-4-(hydroxymethyl)pyrrolidin-...)copy SMILEScopy InChI
Affinity DataKi:  1.10nMAssay Description:Inhibition of human His-tagged PNP assessed as inhibitor constant for enzyme-inhibitor complex formation by measuring reduction in uric acid formatio...More data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM50467705(CHEMBL4282830)copy SMILEScopy InChI
Affinity DataKi:  1.30nMAssay Description:Inhibition of human HGPRT using Prib-PP as substrate by Hanes-plot based methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1571NPubMed
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM50247158(7-(((3S,4S)-3-hydroxy-4-(hydroxymethyl)pyrrolidin-...)copy SMILEScopy InChI
Affinity DataKi:  1.5nMAssay Description:Inhibition of Plasmodium falciparum His-tagged PNP assessed as inhibitor constant for enzyme-inhibitor complex formationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1571NPubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM50519492(CHEMBL1233663)copy SMILEScopy InChI
Affinity DataKi:  1.80nMAssay Description:Inhibition of human HGPRT assessed as inhibitor constant for enzyme-inhibitor-substrate complex formation using [5'-14C]IMP as substrate by scintilla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1571NPubMed
TargetAdenosine deaminase(Plasmodium falciparum)
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM50519494(CHEMBL1234234)copy SMILEScopy InChI
Affinity DataKi:  2.70nMAssay Description:Inhibition of Plasmodium falciparum N-terminal thrombin cleavable His6-tagged ADA expressed in Escherichia coli BL21 assessed as reduction in formati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1571NPubMed
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM50247149(5'-Methylthio-ImmH | CHEMBL473929 | US9290501, (A))copy SMILEScopy InChI
Affinity DataKi:  2.70nMAssay Description:Inhibition of Plasmodium falciparum 3D7 PNP expressed in Escherichia coli assessed as reduction in uric acid formation by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1571NPubMedMMDB
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM50467710(CHEMBL4290716)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Inhibition of human HGPRT using Prib-PP as substrate by Hanes-plot based methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM50519500(CHEMBL1233603)copy SMILEScopy InChI
Affinity DataKi:  4.60nMAssay Description:Inhibition of human HGPRT assessed as inhibitor constant for enzyme-inhibitor-substrate complex formation using [5'-14C]IMP as substrate by scintilla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetAdenosine deaminase(Plasmodium falciparum)
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM22925((8R)-3-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxol...)copy SMILEScopy InChI
Affinity DataKi:  8.20nMAssay Description:Inhibition of Plasmodium falciparum N-terminal thrombin cleavable His6-tagged ADA expressed in Escherichia coli BL21 assessed as reduction in formati...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1571NPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM50293088(7-((2R,3R,4S,5S)-3,4-dihydroxy-5-(hydroxymethyl)py...)copy SMILEScopy InChI
Affinity DataKi:  9nMAssay Description:Inhibition of human PNP assessed as inhibitor constant for enzyme-inhibitor-substrate complex formationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1571NPubMedMMDB
TargetAdenosine deaminase(Homo sapiens (Human))
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM50519494(CHEMBL1234234)copy SMILEScopy InChI
Affinity DataKi: >10nMAssay Description:Inhibition of human erythrocytes ADA assessed as reduction in formation of inosine using adenosine as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1571NPubMed
TargetAdenosine deaminase(Homo sapiens (Human))
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM50367032(COFORMYCIN)copy SMILEScopy InChI
Affinity DataKi:  14nMAssay Description:Inhibition of human erythrocytes ADA assessed as reduction in formation of inosine using adenosine as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1571NPubMed
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM50293088(7-((2R,3R,4S,5S)-3,4-dihydroxy-5-(hydroxymethyl)py...)copy SMILEScopy InChI
Affinity DataKi:  18nMAssay Description:Inhibition of Plasmodium falciparum His-tagged PNP assessed as inhibitor constant for enzyme-inhibitor complex formationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1571NPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM50293086((1S)-1,4-dideoxy-1,4-imino-1-(9-deazaguanin-9-yl)-...)copy SMILEScopy InChI
Affinity DataKi:  29nMAssay Description:Inhibition of human PNP assessed as inhibitor constant for enzyme-inhibitor-substrate complex formationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1571NPubMedMMDB
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM50195587(1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-...)copy SMILEScopy InChI
Affinity DataKi:  29nMAssay Description:Inhibition of Plasmodium falciparum His-tagged PNP assessed as inhibitor constant for enzyme-inhibitor complex formationMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM50293088(7-((2R,3R,4S,5S)-3,4-dihydroxy-5-(hydroxymethyl)py...)copy SMILEScopy InChI
Affinity DataKi:  32nMAssay Description:Inhibition of human PNP assessed as inhibitor constant for enzyme-inhibitor complex formationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1571NPubMedMMDB
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM50519500(CHEMBL1233603)copy SMILEScopy InChI
Affinity DataKi:  56nMAssay Description:Inhibition of human HGPRT assessed as inhibitor constant for enzyme-inhibitor complex formation using [5'-14C]IMP as substrate by scintillation count...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM50195587(1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-...)copy SMILEScopy InChI
Affinity DataKi:  72nMAssay Description:Inhibition of human PNP assessed as inhibitor constant for enzyme-inhibitor-substrate complex formationMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM50247158(7-(((3S,4S)-3-hydroxy-4-(hydroxymethyl)pyrrolidin-...)copy SMILEScopy InChI
Affinity DataKi:  80nMAssay Description:Inhibition of human PNP assessed as inhibitor constant for enzyme-inhibitor-substrate complex formationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1571NPubMedMMDB
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM50519497(CHEMBL4546337)copy SMILEScopy InChI
Affinity DataKi:  100nMAssay Description:Inhibition of human HGPRT using Prib-PP as substrate by Hanes-plot based methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1571NPubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM50519492(CHEMBL1233663)copy SMILEScopy InChI
Affinity DataKi:  250nMAssay Description:Inhibition of human HGPRT assessed as inhibitor constant for enzyme-inhibitor complex formation using [5'-14C]IMP as substrate by scintillation count...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1571NPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM50247149(5'-Methylthio-ImmH | CHEMBL473929 | US9290501, (A))copy SMILEScopy InChI
Affinity DataKi:  303nMAssay Description:Inhibition of human PNP expressed in Escherichia coli assessed as reduction in uric acid formation by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1571NPubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM50519504(CHEMBL4561412)copy SMILEScopy InChI
Affinity DataKi:  400nMAssay Description:Inhibition of human HGPRT using Prib-PP as substrate by Hanes-plot based methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1571NPubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM50519501(CHEMBL4583093)copy SMILEScopy InChI
Affinity DataKi:  600nMAssay Description:Inhibition of human N-terminal His6-tagged HGPRT using Prib-PP as substrate by Hanes-plot based methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM50247158(7-(((3S,4S)-3-hydroxy-4-(hydroxymethyl)pyrrolidin-...)copy SMILEScopy InChI
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition of human PNP assessed as inhibitor constant for enzyme-inhibitor complex formationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1571NPubMedMMDB
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM50519505(CHEMBL4578350)copy SMILEScopy InChI
Affinity DataKi:  6.00E+3nMAssay Description:Inhibition of human N-terminal His6-tagged HGPRT using Prib-PP as substrate by Hanes-plot based methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1571NPubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM50519493(CHEMBL4453040)copy SMILEScopy InChI
Affinity DataKi:  8.00E+3nMAssay Description:Inhibition of human HGPRT using Prib-PP as substrate by Hanes-plot based methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1571NPubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM50519502(CHEMBL4452934)copy SMILEScopy InChI
Affinity DataKi:  1.30E+4nMAssay Description:Inhibition of human N-terminal His6-tagged HGPRT using Prib-PP as substrate by Hanes-plot based methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1571NPubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM50519496(CHEMBL4439813)copy SMILEScopy InChI
Affinity DataKi: >5.00E+5nMAssay Description:Inhibition of human HGPRT using Prib-PP as substrate by Hanes-plot based methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1571NPubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM50519503(CHEMBL2420976)copy SMILEScopy InChI
Affinity DataKi:  7.30E+7nMAssay Description:Inhibition of human HGPRT using Prib-PP as substrate by Hanes-plot based methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1571NPubMed
TargetGMP synthase [glutamine-hydrolyzing](Homo sapiens)
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM50519499(CHEBI:8612 | Psicofuranine)copy SMILEScopy InChI
Affinity DataIC50: 1.73E+4nMAssay Description:Inhibition of human GMP synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1571NPubMed
TargetGMP synthase [glutamine-hydrolyzing](Homo sapiens)
Universit£ Montpellier

Curated by ChEMBL
LigandPNGBDBM50519498(Decoyinine)copy SMILEScopy InChI
Affinity DataIC50: 4.65E+4nMAssay Description:Inhibition of human GMP synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1571NPubMed
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