Target
Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial
Ligand
BDBM23784
Substrate
n/a
Meas. Tech.
ChEMBL_373622 (CHEMBL869762)
Ki
>1000000±n/a nM
Citation
 Nguyen, CRuda, GFSchipani, AKasinathan, GLeal, IMusso-Buendia, AKaiser, MBrun, RRuiz-Pérez, LMSahlberg, BLJohansson, NGGonzalez-Pacanowska, DGilbert, IH Acyclic nucleoside analogues as inhibitors of Plasmodium falciparum dUTPase. J Med Chem 49:4183-95 (2006) [PubMed]  Article
Target
Name:
Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial
Synonyms:
DUT | DUT_HUMAN | Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) | Deoxyuridine triphosphatase (dUTPase) | dUTP pyrophosphatase
Type:
Enzyme
Mol. Mass.:
26574.03
Organism:
Homo sapiens (Human)
Description:
P33316
Residue:
252
Sequence:
MTPLCPRPALCYHFLTSLLRSAMQNARGARQRAEAAVLSGPGPPLGRAAQHGIPRPLSSAGRLSQGCRGASTVGAAGWKGELPKAGGSPAPGPETPAISPSKRARPAEVGGMQLRFARLSEHATAPTRGSARAAGYDLYSAYDYTIPPMEKAVVKTDIQIALPSGCYGRVAPRSGLAAKHFIDVGAGVIDEDYRGNVGVVLFNFGKEKFEVKKGDRIAQLICERIFYPEIEEVQALDDTERGSGGFGSTGKN
  
Inhibitor
Name:
BDBM23784
Synonyms:
CHEMBL118166 | Triphenylmethyl-containing compound, 13 | triphenylmethanol
Type:
Small organic molecule
Emp. Form.:
C19H16O
Mol. Mass.:
260.3297
SMILES:
OC(c1ccccc1)(c1ccccc1)c1ccccc1
Structure:
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