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Target
Matrix protein 2
Ligand
BDBM50216627
Substrate
n/a
Meas. Tech.
ChEMBL_2300456
Kd
510±n/a nM
Citation
 Drakopoulos, A; Tzitzoglaki, C; Ma, C; Freudenberger, K; Hoffmann, A; Hu, Y; Gauglitz, G; Schmidtke, M; Wang, J; Kolocouris, A Affinity of Rimantadine Enantiomers against Influenza A/M2 Protein Revisited. ACS Med Chem Lett 8:145-150 (2017) [PubMed]
Target
Name:
Matrix protein 2
Synonyms:
M | Matrix protein 2 | Proton channel protein M2
Type:
PROTEIN
Mol. Mass.:
11043.57
Organism:
Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)
Description:
ChEMBL_104398
Residue:
97
Sequence:
MSLLTEVETPIRNEWGCRCNGSSDPLAIAANIIGILHLILWILDRLFFKCIYRRFKYGLKGGPSTEGVPKSMREEYRKEQQSAVDADDGHFVSIELE
  
Inhibitor
Name:
BDBM50216627
Synonyms:
(alpha-methyl-1-adamantyl)methylamine | 1-Adamantan-1-yl-ethylamine | CHEMBL959 | RIMANTADINE | US11241393, Rimantadine | rimantadin | rimantidin
Type:
Small organic molecule
Emp. Form.:
C12H21N
Mol. Mass.:
179.3018
SMILES:
CC(N)C12CC3CC(CC(C3)C1)C2 |TLB:10:5:12:9.8.11,10:9:12:6.5.4,THB:4:5:8:12.3.11,4:3:6.5.10:8,1:3:6.5.10:8|
Structure:
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