Reaction Details  Report a problem with these data
Target
Ribonuclease HI
Ligand
BDBM50187665
Substrate
n/a
Meas. Tech.
ChEMBL_744865 (CHEMBL1772886)
IC50
>20000±n/a nM
Citation
 Kim, JA; Yang, SY; Wamiru, A; McMahon, JB; Le Grice, SF; Beutler, JA; Kim, YH New monoterpene glycosides and phenolic compounds from Distylium racemosum and their inhibitory activity against ribonuclease H. Bioorg Med Chem Lett 21:2840-4 (2011) [PubMed]  Article
Target
Name:
Ribonuclease HI
Synonyms:
RNH_ECOLI | RNase H | Ribonuclease H | Ribonuclease HI | dasF | herA | rnh | rnhA | sdrA
Type:
Enzyme
Mol. Mass.:
17601.33
Organism:
Escherichia coli (strain K12)
Description:
n/a
Residue:
155
Sequence:
MLKQVEIFTDGSCLGNPGPGGYGAILRYRGREKTFSAGYTRTTNNRMELMAAIVALEALKEHCEVILSTDSQYVRQGITQWIHNWKKRGWKTADKKPVKNVDLWQRLDAALGQHQIKWEWVKGHAGHPENERCDELARAAAMNPTLEDTGYQVEV
  
Inhibitor
Name:
BDBM50187665
Synonyms:
(-)-epigallocatechin | CHEMBL47386
Type:
Small organic molecule
Emp. Form.:
C15H14O7
Mol. Mass.:
306.2675
SMILES:
O[C@@H]1Cc2c(O)cc(O)cc2O[C@@H]1c1cc(O)c(O)c(O)c1 |r|
Structure:
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