Compile Data Set for Download or QSAR
Found 213 of affinity data for UniProtKB/TrEMBL: P55157
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391864(CHEMBL2147287)copy SMILEScopy InChI
Affinity DataIC50: 0nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as unbound drug level causing inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391863(CHEMBL2147286)copy SMILEScopy InChI
Affinity DataIC50: 0.00100nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as unbound drug level causing inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391858(CHEMBL2147281)copy SMILEScopy InChI
Affinity DataIC50: 0.00100nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as unbound drug level causing inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391867(CHEMBL2147290)copy SMILEScopy InChI
Affinity DataIC50: 0.00200nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as unbound drug level causing inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391860(CHEMBL2147283)copy SMILEScopy InChI
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as unbound drug level causing inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50204367(CHEMBL410414 | dirlotapide)copy SMILEScopy InChI
Affinity DataIC50: 0.0110nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as unbound drug level causing inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50098322(9-(4-{5-Methyl-4-[(4'-trifluoromethyl-biphenyl-2-c...)copy SMILEScopy InChI
Affinity DataIC50: 0.0200nMAssay Description:In vitro inhibition of human microsomal triglyceride transfer protein in HepG2 cells using apoB secretion assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N015S8PubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391875(CHEMBL2147296)copy SMILEScopy InChI
Affinity DataIC50: 0.0210nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as unbound drug level causing inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391876(CHEMBL2147292)copy SMILEScopy InChI
Affinity DataIC50: 0.0250nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as unbound drug level causing inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50098321(9-(4-{2,5-Dimethyl-4-[(4'-trifluoromethyl-biphenyl...)copy SMILEScopy InChI
Affinity DataIC50: 0.0300nMAssay Description:In vitro inhibition of human microsomal triglyceride transfer protein in HepG2 cells using apoB secretion assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N015S8PubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391866(CHEMBL2147294)copy SMILEScopy InChI
Affinity DataIC50: 0.0580nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as unbound drug level causing inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50098326(9-(4-{2-Isopropyl-4-[(4'-trifluoromethyl-biphenyl-...)copy SMILEScopy InChI
Affinity DataIC50: 0.0600nMAssay Description:In vitro inhibition of human microsomal triglyceride transfer protein in HepG2 cells using apoB secretion assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N015S8PubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391877(CHEMBL2147293)copy SMILEScopy InChI
Affinity DataIC50: 0.0660nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as unbound drug level causing inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391869(CHEMBL2147301)copy SMILEScopy InChI
Affinity DataIC50: 0.101nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as unbound drug level causing inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391871(CHEMBL2147298)copy SMILEScopy InChI
Affinity DataIC50: 0.105nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as unbound drug level causing inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391872(CHEMBL2147299)copy SMILEScopy InChI
Affinity DataIC50: 0.122nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as unbound drug level causing inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50098324(9-(4-{2-Methyl-4-[(4'-trifluoromethyl-biphenyl-2-c...)copy SMILEScopy InChI
Affinity DataIC50: 0.150nMAssay Description:In vitro inhibition of human microsomal triglyceride transfer protein in HepG2 cells using apoB secretion assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N015S8PubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50098325(9-(4-{4-[(4'-Trifluoromethyl-biphenyl-2-carbonyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 0.240nMAssay Description:In vitro inhibition of human microsomal triglyceride transfer protein in HepG2 cells using apoB secretion assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N015S8PubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391874(CHEMBL2147295)copy SMILEScopy InChI
Affinity DataIC50: 0.253nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as unbound drug level causing inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391857(CHEMBL2147280)copy SMILEScopy InChI
Affinity DataIC50: 0.345nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as unbound drug level causing inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391856(CHEMBL2147279)copy SMILEScopy InChI
Affinity DataIC50: 0.378nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as unbound drug level causing inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391862(CHEMBL2147285)copy SMILEScopy InChI
Affinity DataIC50: 0.440nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391870(CHEMBL2147300)copy SMILEScopy InChI
Affinity DataIC50: 0.484nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as unbound drug level causing inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391861(CHEMBL2147284)copy SMILEScopy InChI
Affinity DataIC50: 0.550nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391875(CHEMBL2147296)copy SMILEScopy InChI
Affinity DataIC50: 0.560nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391863(CHEMBL2147286)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50277189((R)-6-methyl-N-(2-(thiazol-2-ylmethylamino)-2,3-di...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as apolipoprotein B production by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29887ZNPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391869(CHEMBL2147301)copy SMILEScopy InChI
Affinity DataIC50: 0.630nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391858(CHEMBL2147281)copy SMILEScopy InChI
Affinity DataIC50: 0.740nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391867(CHEMBL2147290)copy SMILEScopy InChI
Affinity DataIC50: 0.770nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50098320(9-(4-{4-[(4''-Trifluoromethyl-biphenyl-2-carbonyl)...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:In vitro inhibition of human microsomal triglyceride transfer protein in HepG2 cells using apoB secretion assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N015S8PubMedDrugBank
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391865(CHEMBL2147291)copy SMILEScopy InChI
Affinity DataIC50: 0.830nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50107789((R)-methyl 5-(6-methyl-4'-(trifluoromethyl)bipheny...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as apolipoprotein B production by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29887ZNPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50098322(9-(4-{5-Methyl-4-[(4'-trifluoromethyl-biphenyl-2-c...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:In vitro inhibition of human Microsomal Triglyceride Transfer Protein, (triglyceride transfer assay)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N015S8PubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50098324(9-(4-{2-Methyl-4-[(4'-trifluoromethyl-biphenyl-2-c...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:In vitro inhibition of human Microsomal Triglyceride Transfer Protein, (triglyceride transfer assay)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N015S8PubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50098321(9-(4-{2,5-Dimethyl-4-[(4'-trifluoromethyl-biphenyl...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:In vitro inhibition of human Microsomal Triglyceride Transfer Protein, (triglyceride transfer assay)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N015S8PubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50184105(4'-trifluoromethyl-biphenyl-2-carboxylic acid (4-{...)copy SMILEScopy InChI
Affinity DataIC50: 1.01nMAssay Description:Inhibition of MTP in canine liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D21X68PubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391876(CHEMBL2147292)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391873(CHEMBL2147297)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391864(CHEMBL2147287)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391873(CHEMBL2147297)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391868(CHEMBL2146489)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391868(CHEMBL2146489)copy SMILEScopy InChI
Affinity DataIC50: 1.21nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391857(CHEMBL2147280)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50184109(4'-trifluoromethyl-biphenyl-2-carboxylic acid {2-m...)copy SMILEScopy InChI
Affinity DataIC50: 1.64nMAssay Description:Inhibition of MTP in canine liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D21X68PubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50184153(4'-trifluoromethyl-biphenyl-2-carboxylic acid (4-{...)copy SMILEScopy InChI
Affinity DataIC50: 1.68nMAssay Description:Inhibition of MTP in canine liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D21X68PubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50184111(4'-trifluoromethyl-biphenyl-2-carboxylic acid [2-m...)copy SMILEScopy InChI
Affinity DataIC50: 1.75nMAssay Description:Inhibition of MTP in canine liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D21X68PubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50184165(4'-trifluoromethyl-biphenyl-2-carboxylic acid (4-{...)copy SMILEScopy InChI
Affinity DataIC50: 1.78nMAssay Description:Inhibition of MTP in canine liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D21X68PubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50391856(CHEMBL2147279)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27WCRPubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50098323(9-(4-{2-Propyl-4-[(4'-trifluoromethyl-biphenyl-2-c...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:In vitro inhibition of human Microsomal Triglyceride Transfer Protein, (triglyceride transfer assay)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N015S8PubMed
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