Compile Data Set for Download or QSAR

Found 816 hits for UniProtKB: O00255   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Menin (Homo sapiens (Human))	BDBM50516569 (CHEMBL4585198 | US10899738, Cpd. No 148) Show SMILES CCN1Cc2ccccc2C(C1)(C1CCCC1)C1CCN(CC2CN(C2)c2ccc(cc2)S(=O)(=O)c2ccncc2)CC1 Show InChI InChI=1S/C36H46N4O2S/c1-2-38-26-29-7-3-6-10-35(29)36(27-38,30-8-4-5-9-30)31-17-21-39(22-18-31)23-28-24-40(25-28)32-11-13-33(14-12-32)43(41,42)34-15-19-37-20-16-34/h3,6-7,10-16,19-20,28,30-31H,2,4-5,8-9,17-18,21-27H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516582 (CHEMBL4449381) Show SMILES [H][C@@]1(CCC[C@@H]1OC(=O)NC)[C@@]1(CN(C)Cc2ccccc12)C1CCN(CC2CN(C2)c2ccc(cc2)S(=O)(=O)c2ccncc2)CC1 |r| Show InChI InChI=1S/C37H47N5O4S/c1-38-36(43)46-35-9-5-8-34(35)37(26-40(2)25-28-6-3-4-7-33(28)37)29-16-20-41(21-17-29)22-27-23-42(24-27)30-10-12-31(13-11-30)47(44,45)32-14-18-39-19-15-32/h3-4,6-7,10-15,18-19,27,29,34-35H,5,8-9,16-17,20-26H2,1-2H3,(H,38,43)/t34-,35-,37-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	<1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair				3D Structure (crystal)
Menin (Homo sapiens (Human))	BDBM50516571 (CHEMBL4592636 | US10899738, Cpd. No 50) Show SMILES O=S(=O)(c1ccncc1)c1ccc(cc1)N1CC(CN2CCC(CC2)C2(CN(CC3CC3)Cc3ccccc23)C2CCCC2)C1 Show InChI InChI=1S/C38H48N4O2S/c43-45(44,36-15-19-39-20-16-36)35-13-11-34(12-14-35)42-25-30(26-42)24-40-21-17-33(18-22-40)38(32-6-2-3-7-32)28-41(23-29-9-10-29)27-31-5-1-4-8-37(31)38/h1,4-5,8,11-16,19-20,29-30,32-33H,2-3,6-7,9-10,17-18,21-28H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516570 (CHEMBL4551865 | US10899738, Cpd. No 48) Show SMILES CC(C)N1Cc2ccccc2C(C1)(C1CCCC1)C1CCN(CC2CN(C2)c2ccc(cc2)S(=O)(=O)c2ccncc2)CC1 Show InChI InChI=1S/C37H48N4O2S/c1-28(2)41-26-30-7-3-6-10-36(30)37(27-41,31-8-4-5-9-31)32-17-21-39(22-18-32)23-29-24-40(25-29)33-11-13-34(14-12-33)44(42,43)35-15-19-38-20-16-35/h3,6-7,10-16,19-20,28-29,31-32H,4-5,8-9,17-18,21-27H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516567 (CHEMBL4449199 | US10899738, Cpd. No 51) Show SMILES O=S(=O)(c1ccncc1)c1ccc(cc1)N1CC(CN2CCC(CC2)C2(CNCc3ccccc23)C2CCCC2)C1 Show InChI InChI=1S/C34H42N4O2S/c39-41(40,32-13-17-35-18-14-32)31-11-9-30(10-12-31)38-23-26(24-38)22-37-19-15-29(16-20-37)34(28-6-2-3-7-28)25-36-21-27-5-1-4-8-33(27)34/h1,4-5,8-14,17-18,26,28-29,36H,2-3,6-7,15-16,19-25H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516568 (CHEMBL4516680) Show SMILES CN1Cc2ccccc2C(C1)(C1CCCC1)C1CCN(CC2CN(C2)c2ccc(cc2)S(=O)(=O)c2ccncc2)CC1 Show InChI InChI=1S/C35H44N4O2S/c1-37-25-28-6-2-5-9-34(28)35(26-37,29-7-3-4-8-29)30-16-20-38(21-17-30)22-27-23-39(24-27)31-10-12-32(13-11-31)42(40,41)33-14-18-36-19-15-33/h2,5-6,9-15,18-19,27,29-30H,3-4,7-8,16-17,20-26H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516554 (CHEMBL4522767 | US10899738, Cpd. No 49) Show SMILES O=S(=O)(c1ccncc1)c1ccc(cc1)N1CC(CN2CCC(CC2)C2(CN(Cc3ccccc23)C2CCC2)C2CCCC2)C1 Show InChI InChI=1S/C38H48N4O2S/c43-45(44,36-16-20-39-21-17-36)35-14-12-34(13-15-35)41-25-29(26-41)24-40-22-18-32(19-23-40)38(31-7-2-3-8-31)28-42(33-9-5-10-33)27-30-6-1-4-11-37(30)38/h1,4,6,11-17,20-21,29,31-33H,2-3,5,7-10,18-19,22-28H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516565 (CHEMBL4578509 | US10899738, Cpd. No 92) Show SMILES O=S(=O)(C1CCCCC1)c1ccc(cc1)N1CC(CN2CCC(CC2)C2(NCCc3ccccc23)C2CCCC2)C1 Show InChI InChI=1S/C35H49N3O2S/c39-41(40,32-11-2-1-3-12-32)33-16-14-31(15-17-33)38-25-27(26-38)24-37-22-19-30(20-23-37)35(29-9-5-6-10-29)34-13-7-4-8-28(34)18-21-36-35/h4,7-8,13-17,27,29-30,32,36H,1-3,5-6,9-12,18-26H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516574 (CHEMBL4444304 | US10899738, Cpd. No 54) Show SMILES O=S(=O)(c1ccncc1)c1ccc(cc1)N1CC(CN2CCC(CC2)C2(CN(CCN3CCOCC3)Cc3ccccc23)C2CCCC2)C1 Show InChI InChI=1S/C40H53N5O3S/c46-49(47,38-13-17-41-18-14-38)37-11-9-36(10-12-37)45-28-32(29-45)27-43-19-15-35(16-20-43)40(34-6-2-3-7-34)31-44(22-21-42-23-25-48-26-24-42)30-33-5-1-4-8-39(33)40/h1,4-5,8-14,17-18,32,34-35H,2-3,6-7,15-16,19-31H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516581 (CHEMBL4458829) Show SMILES [H][C@@]1(CCC[C@@H]1OC(=O)NC)[C@@](C#N)(C1CCN(CC2CN(C2)c2ccc(cc2)C#N)CC1)c1ccccc1 |r| Show InChI InChI=1S/C31H37N5O2/c1-34-30(37)38-29-9-5-8-28(29)31(22-33,25-6-3-2-4-7-25)26-14-16-35(17-15-26)19-24-20-36(21-24)27-12-10-23(18-32)11-13-27/h2-4,6-7,10-13,24,26,28-29H,5,8-9,14-17,19-21H2,1H3,(H,34,37)/t28-,29-,31+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50489239 (CHEMBL2314823) Show SMILES C[C@@H](O)[C@H](NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O |r| Show InChI InChI=1S/C73H116N30O15/c1-39(59(109)98-50(24-13-31-89-73(83)84)67(117)102-32-14-25-53(102)64(114)91-38-56(107)101-57(40(2)104)66(116)92-37-55(106)95-48(22-11-29-87-71(79)80)61(111)96-46(58(74)108)20-9-27-85-69(75)76)93-65(115)54-26-15-33-103(54)68(118)52(34-42-16-5-4-6-17-42)100-62(112)49(23-12-30-88-72(81)82)97-63(113)51(35-43-36-90-45-19-8-7-18-44(43)45)99-60(110)47(94-41(3)105)21-10-28-86-70(77)78/h4-8,16-19,36,39-40,46-54,57,90,104H,9-15,20-35,37-38H2,1-3H3,(H2,74,108)(H,91,114)(H,92,116)(H,93,115)(H,94,105)(H,95,106)(H,96,111)(H,97,113)(H,98,109)(H,99,110)(H,100,112)(H,101,107)(H4,75,76,85)(H4,77,78,86)(H4,79,80,87)(H4,81,82,88)(H4,83,84,89)/t39-,40+,46-,47-,48-,49-,50-,51-,52-,53-,54-,57-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to menin (unknown origin) after 60 mins by fluorescence polarization assay				J Med Chem 56: 1113-23 (2013) Article DOI: 10.1021/jm3015298 BindingDB Entry DOI: 10.7270/Q22B91XM
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516553 (CHEMBL4476073 | US10899738, Cpd. No 151) Show SMILES O=S(=O)(c1ccncc1)c1ccc(cc1)N1CC(CN2CCC(CC2)C2(NCCc3ccccc23)C2CCCC2)C1 Show InChI InChI=1S/C34H42N4O2S/c39-41(40,32-14-18-35-19-15-32)31-11-9-30(10-12-31)38-24-26(25-38)23-37-21-16-29(17-22-37)34(28-6-2-3-7-28)33-8-4-1-5-27(33)13-20-36-34/h1,4-5,8-12,14-15,18-19,26,28-29,36H,2-3,6-7,13,16-17,20-25H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516564 (CHEMBL4459554 | US10899738, Cpd. No 146) Show SMILES O=S(=O)(C1CCCC1)c1ccc(cc1)N1CC(CN2CCC(CC2)C2(NCCc3ccccc23)C2CCCC2)C1 Show InChI InChI=1S/C34H47N3O2S/c38-40(39,31-10-4-5-11-31)32-15-13-30(14-16-32)37-24-26(25-37)23-36-21-18-29(19-22-36)34(28-8-2-3-9-28)33-12-6-1-7-27(33)17-20-35-34/h1,6-7,12-16,26,28-29,31,35H,2-5,8-11,17-25H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50489254 (CHEMBL2314819) Show SMILES [H][C@@]12CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)C1(CCC1)NC(=O)[C@]1([H])CCCN1C(=O)[C@H](Cc1cc(F)cc(F)c1)NC(=O)[C@@H](N)CCCCCCCCNC2=O |r| Show InChI InChI=1S/C40H60F2N10O6/c41-26-21-25(22-27(42)24-26)23-30-37(57)52-20-9-14-32(52)35(55)50-40(15-10-16-40)38(58)49-29(12-7-18-47-39(44)45)36(56)51-19-8-13-31(51)34(54)46-17-6-4-2-1-3-5-11-28(43)33(53)48-30/h21-22,24,28-32H,1-20,23,43H2,(H,46,54)(H,48,53)(H,49,58)(H,50,55)(H4,44,45,47)/t28-,29-,30-,31-,32-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to menin (unknown origin) after 60 mins by fluorescence polarization assay				J Med Chem 56: 1113-23 (2013) Article DOI: 10.1021/jm3015298 BindingDB Entry DOI: 10.7270/Q22B91XM
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516566 (CHEMBL4436641 | US10899738, Cpd. No 149) Show SMILES O=S(=O)(c1ccccc1)c1ccc(cc1)N1CC(CN2CCC(CC2)C2(NCCc3ccccc23)C2CCCC2)C1 Show InChI InChI=1S/C35H43N3O2S/c39-41(40,32-11-2-1-3-12-32)33-16-14-31(15-17-33)38-25-27(26-38)24-37-22-19-30(20-23-37)35(29-9-5-6-10-29)34-13-7-4-8-28(34)18-21-36-35/h1-4,7-8,11-17,27,29-30,36H,5-6,9-10,18-26H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50489255 (CHEMBL2314816) Show SMILES [H][C@@]12CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)C1(CCC1)NC(=O)[C@]1([H])CCCN1C(=O)[C@H](Cc1cccc(F)c1)NC(=O)[C@@H](N)CCCCCCCCNC2=O |r| Show InChI InChI=1S/C40H61FN10O6/c41-27-13-7-12-26(24-27)25-30-37(56)51-23-10-17-32(51)35(54)49-40(18-11-19-40)38(57)48-29(15-8-21-46-39(43)44)36(55)50-22-9-16-31(50)34(53)45-20-6-4-2-1-3-5-14-28(42)33(52)47-30/h7,12-13,24,28-32H,1-6,8-11,14-23,25,42H2,(H,45,53)(H,47,52)(H,48,57)(H,49,54)(H4,43,44,46)/t28-,29-,30-,31-,32-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to menin (unknown origin) after 60 mins by fluorescence polarization assay				J Med Chem 56: 1113-23 (2013) Article DOI: 10.1021/jm3015298 BindingDB Entry DOI: 10.7270/Q22B91XM
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50489248 (CHEMBL2314833) Show SMILES [H][C@@]12CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@]1([H])CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCCCCCCNC2=O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O |r| Show InChI InChI=1S/C57H84N16O9/c1-35-48(75)69-43(24-15-29-64-57(60)61)54(81)72-30-16-25-46(72)52(79)62-27-13-6-4-3-5-10-22-42(50(77)71-45(32-37-18-8-7-9-19-37)55(82)73-31-17-26-47(73)53(80)66-35)68-51(78)44(33-38-34-65-40-21-12-11-20-39(38)40)70-49(76)41(67-36(2)74)23-14-28-63-56(58)59/h7-9,11-12,18-21,34-35,41-47,65H,3-6,10,13-17,22-33H2,1-2H3,(H,62,79)(H,66,80)(H,67,74)(H,68,78)(H,69,75)(H,70,76)(H,71,77)(H4,58,59,63)(H4,60,61,64)/t35-,41-,42-,43-,44-,45-,46-,47-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to menin (unknown origin) after 60 mins by fluorescence polarization assay				J Med Chem 56: 1113-23 (2013) Article DOI: 10.1021/jm3015298 BindingDB Entry DOI: 10.7270/Q22B91XM
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516572 (CHEMBL4532417 | US10899738, Cpd. No 52) Show SMILES O=S(=O)(c1ccncc1)c1ccc(cc1)N1CC(CN2CCC(CC2)C2(CN(CC3COC3)Cc3ccccc23)C2CCCC2)C1 Show InChI InChI=1S/C38H48N4O3S/c43-46(44,36-13-17-39-18-14-36)35-11-9-34(10-12-35)42-23-29(24-42)21-40-19-15-33(16-20-40)38(32-6-2-3-7-32)28-41(22-30-26-45-27-30)25-31-5-1-4-8-37(31)38/h1,4-5,8-14,17-18,29-30,32-33H,2-3,6-7,15-16,19-28H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516549 (CHEMBL4470192 | US10899738, Cpd. No 135) Show SMILES O=S(=O)(C1CC1)c1ccc(cc1)N1CC(CN2CCC(CC2)C2(NCCc3ccccc23)C2CCCC2)C1 Show InChI InChI=1S/C32H43N3O2S/c36-38(37,30-13-14-30)29-11-9-28(10-12-29)35-22-24(23-35)21-34-19-16-27(17-20-34)32(26-6-2-3-7-26)31-8-4-1-5-25(31)15-18-33-32/h1,4-5,8-12,24,26-27,30,33H,2-3,6-7,13-23H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516583 (CHEMBL4568235) Show SMILES [H][C@@]1(CCC[C@@H]1NC(=O)OC)[C@@](C#N)(C1CCN(CC2CN(C2)c2ccc(cc2)C#N)CC1)c1ccccc1 |r| Show InChI InChI=1S/C31H37N5O2/c1-38-30(37)34-29-9-5-8-28(29)31(22-33,25-6-3-2-4-7-25)26-14-16-35(17-15-26)19-24-20-36(21-24)27-12-10-23(18-32)11-13-27/h2-4,6-7,10-13,24,26,28-29H,5,8-9,14-17,19-21H2,1H3,(H,34,37)/t28-,29-,31+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	8.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516579 (CHEMBL4452253) Show SMILES [H][C@@]1(CCC[C@@H]1OC(=O)CC)[C@@](C#N)(C1CCN(CC2CN(C2)c2ccc(cc2)C#N)CC1)c1ccccc1 |r| Show InChI InChI=1S/C32H38N4O2/c1-2-31(37)38-30-10-6-9-29(30)32(23-34,26-7-4-3-5-8-26)27-15-17-35(18-16-27)20-25-21-36(22-25)28-13-11-24(19-33)12-14-28/h3-5,7-8,11-14,25,27,29-30H,2,6,9-10,15-18,20-22H2,1H3/t29-,30-,32+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	9.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516561 (CHEMBL4460234 | US10899738, Cpd. No 133) Show SMILES CCS(=O)(=O)c1ccc(cc1)N1CC(CN2CCC(CC2)C2(NCCc3ccccc23)C2CCCC2)C1 Show InChI InChI=1S/C31H43N3O2S/c1-2-37(35,36)29-13-11-28(12-14-29)34-22-24(23-34)21-33-19-16-27(17-20-33)31(26-8-4-5-9-26)30-10-6-3-7-25(30)15-18-32-31/h3,6-7,10-14,24,26-27,32H,2,4-5,8-9,15-23H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516563 (CHEMBL4581439 | US10899738, Cpd. No 85) Show SMILES O=S(=O)(C1CCC1)c1ccc(cc1)N1CC(CN2CCC(CC2)C2(NCCc3ccccc23)C2CCCC2)C1 Show InChI InChI=1S/C33H45N3O2S/c37-39(38,30-9-5-10-30)31-14-12-29(13-15-31)36-23-25(24-36)22-35-20-17-28(18-21-35)33(27-7-2-3-8-27)32-11-4-1-6-26(32)16-19-34-33/h1,4,6,11-15,25,27-28,30,34H,2-3,5,7-10,16-24H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516559 (CHEMBL4446177 | US10899738, Cpd. No 129) Show SMILES N#Cc1ccc(cc1)N1CC(CN2CCC(CC2)C2(NCCc3ccccc23)C2CCCC2)C1 Show InChI InChI=1S/C30H38N4/c31-19-23-9-11-28(12-10-23)34-21-24(22-34)20-33-17-14-27(15-18-33)30(26-6-2-3-7-26)29-8-4-1-5-25(29)13-16-32-30/h1,4-5,8-12,24,26-27,32H,2-3,6-7,13-18,20-22H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516578 (CHEMBL4453006) Show SMILES [H][C@@]1(CCC[C@@H]1OC(C)=O)[C@@](C#N)(C1CCN(CC2CN(C2)c2ccc(cc2)C#N)CC1)c1ccccc1 |r| Show InChI InChI=1S/C31H36N4O2/c1-23(36)37-30-9-5-8-29(30)31(22-33,26-6-3-2-4-7-26)27-14-16-34(17-15-27)19-25-20-35(21-25)28-12-10-24(18-32)11-13-28/h2-4,6-7,10-13,25,27,29-30H,5,8-9,14-17,19-21H2,1H3/t29-,30-,31+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50489256 (CHEMBL2314830) Show SMILES [H][C@@]12CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@]1([H])CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCCCCNC2=O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O |r| Show InChI InChI=1S/C55H80N16O9/c1-33-46(73)67-41(22-13-27-62-55(58)59)52(79)70-28-14-23-44(70)50(77)60-25-11-4-3-8-20-40(48(75)69-43(30-35-16-6-5-7-17-35)53(80)71-29-15-24-45(71)51(78)64-33)66-49(76)42(31-36-32-63-38-19-10-9-18-37(36)38)68-47(74)39(65-34(2)72)21-12-26-61-54(56)57/h5-7,9-10,16-19,32-33,39-45,63H,3-4,8,11-15,20-31H2,1-2H3,(H,60,77)(H,64,78)(H,65,72)(H,66,76)(H,67,73)(H,68,74)(H,69,75)(H4,56,57,61)(H4,58,59,62)/t33-,39-,40-,41-,42-,43-,44-,45-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to menin (unknown origin) after 60 mins by fluorescence polarization assay				J Med Chem 56: 1113-23 (2013) Article DOI: 10.1021/jm3015298 BindingDB Entry DOI: 10.7270/Q22B91XM
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516562 (CHEMBL4467100 | US10899738, Cpd. No 134) Show SMILES CC(C)S(=O)(=O)c1ccc(cc1)N1CC(CN2CCC(CC2)C2(NCCc3ccccc23)C2CCCC2)C1 Show InChI InChI=1S/C32H45N3O2S/c1-24(2)38(36,37)30-13-11-29(12-14-30)35-22-25(23-35)21-34-19-16-28(17-20-34)32(27-8-4-5-9-27)31-10-6-3-7-26(31)15-18-33-32/h3,6-7,10-14,24-25,27-28,33H,4-5,8-9,15-23H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516547 (CHEMBL4448045 | US10899738, Cpd. No 27) Show SMILES N#Cc1ccc(OCCCN2CCC(CC2)C2(NCCc3ccccc23)C2CCCC2)cc1 Show InChI InChI=1S/C29H37N3O/c30-22-23-10-12-27(13-11-23)33-21-5-18-32-19-15-26(16-20-32)29(25-7-2-3-8-25)28-9-4-1-6-24(28)14-17-31-29/h1,4,6,9-13,25-26,31H,2-3,5,7-8,14-21H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50489251 (CHEMBL2314829) Show SMILES [H][C@@]12CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@]1([H])CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCCCCCCCCNC2=O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O |r| Show InChI InChI=1S/C59H88N16O9/c1-37-50(77)71-45(26-17-31-66-59(62)63)56(83)74-32-18-27-48(74)54(81)64-29-15-8-6-4-3-5-7-12-24-44(52(79)73-47(34-39-20-10-9-11-21-39)57(84)75-33-19-28-49(75)55(82)68-37)70-53(80)46(35-40-36-67-42-23-14-13-22-41(40)42)72-51(78)43(69-38(2)76)25-16-30-65-58(60)61/h9-11,13-14,20-23,36-37,43-49,67H,3-8,12,15-19,24-35H2,1-2H3,(H,64,81)(H,68,82)(H,69,76)(H,70,80)(H,71,77)(H,72,78)(H,73,79)(H4,60,61,65)(H4,62,63,66)/t37-,43-,44-,45-,46-,47-,48-,49-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to menin (unknown origin) after 60 mins by fluorescence polarization assay				J Med Chem 56: 1113-23 (2013) Article DOI: 10.1021/jm3015298 BindingDB Entry DOI: 10.7270/Q22B91XM
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516548 (CHEMBL4466955 | US10899738, Cpd. No 113) Show SMILES N#Cc1ccc(cc1)N1CCC(CN2CCC(CC2)C2(NCCc3ccccc23)C2CCCC2)C1 Show InChI InChI=1S/C31H40N4/c32-21-24-9-11-29(12-10-24)35-20-14-25(23-35)22-34-18-15-28(16-19-34)31(27-6-2-3-7-27)30-8-4-1-5-26(30)13-17-33-31/h1,4-5,8-12,25,27-28,33H,2-3,6-7,13-20,22-23H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50489253 (CHEMBL2314569) Show SMILES [H][C@@]12CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)C1(CCC1)NC(=O)[C@]1([H])CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCCCCCCNC2=O |r| Show InChI InChI=1S/C40H62N10O6/c41-28-16-8-3-1-2-4-9-22-44-34(52)31-18-11-24-49(31)36(54)29(17-10-23-45-39(42)43)47-38(56)40(20-13-21-40)48-35(53)32-19-12-25-50(32)37(55)30(46-33(28)51)26-27-14-6-5-7-15-27/h5-7,14-15,28-32H,1-4,8-13,16-26,41H2,(H,44,52)(H,46,51)(H,47,56)(H,48,53)(H4,42,43,45)/t28-,29-,30-,31-,32-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to menin (unknown origin) after 60 mins by fluorescence polarization assay				J Med Chem 56: 1113-23 (2013) Article DOI: 10.1021/jm3015298 BindingDB Entry DOI: 10.7270/Q22B91XM
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50489225 (CHEMBL2314817) Show SMILES [H][C@@]12CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)C1(CCC1)NC(=O)[C@]1([H])CCCN1C(=O)[C@H](Cc1ccccc1F)NC(=O)[C@@H](N)CCCCCCCCNC2=O |r| Show InChI InChI=1S/C40H61FN10O6/c41-27-14-7-6-13-26(27)25-30-37(56)51-24-11-18-32(51)35(54)49-40(19-12-20-40)38(57)48-29(16-9-22-46-39(43)44)36(55)50-23-10-17-31(50)34(53)45-21-8-4-2-1-3-5-15-28(42)33(52)47-30/h6-7,13-14,28-32H,1-5,8-12,15-25,42H2,(H,45,53)(H,47,52)(H,48,57)(H,49,54)(H4,43,44,46)/t28-,29-,30-,31-,32-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to menin (unknown origin) after 60 mins by fluorescence polarization assay				J Med Chem 56: 1113-23 (2013) Article DOI: 10.1021/jm3015298 BindingDB Entry DOI: 10.7270/Q22B91XM
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50489229 (CHEMBL2314572) Show SMILES [H][C@@]12CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)C1(CCC1)NC(=O)[C@]1([H])CCCN1C(=O)[C@H](Cc1ccccc1Cl)NC(=O)[C@@H](N)CCCCCCCCNC2=O |r| Show InChI InChI=1S/C40H61ClN10O6/c41-27-14-7-6-13-26(27)25-30-37(56)51-24-11-18-32(51)35(54)49-40(19-12-20-40)38(57)48-29(16-9-22-46-39(43)44)36(55)50-23-10-17-31(50)34(53)45-21-8-4-2-1-3-5-15-28(42)33(52)47-30/h6-7,13-14,28-32H,1-5,8-12,15-25,42H2,(H,45,53)(H,47,52)(H,48,57)(H,49,54)(H4,43,44,46)/t28-,29-,30-,31-,32-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to menin (unknown origin) after 60 mins by fluorescence polarization assay				J Med Chem 56: 1113-23 (2013) Article DOI: 10.1021/jm3015298 BindingDB Entry DOI: 10.7270/Q22B91XM
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516552 (CHEMBL4565646) Show SMILES [H][C@@]1(CCC[C@@H]1NC(C)=O)[C@@](C#N)(C1CCN(CC2CN(C2)c2ccc(cc2)C#N)CC1)c1ccccc1 |r| Show InChI InChI=1S/C31H37N5O/c1-23(37)34-30-9-5-8-29(30)31(22-33,26-6-3-2-4-7-26)27-14-16-35(17-15-27)19-25-20-36(21-25)28-12-10-24(18-32)11-13-28/h2-4,6-7,10-13,25,27,29-30H,5,8-9,14-17,19-21H2,1H3,(H,34,37)/t29-,30-,31+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50489247 (CHEMBL2314834) Show SMILES [H][C@@]12CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@]1([H])CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCCCCCCCNC2=O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O |r| Show InChI InChI=1S/C58H86N16O9/c1-36-49(76)70-44(25-16-30-65-58(61)62)55(82)73-31-17-26-47(73)53(80)63-28-14-7-5-3-4-6-11-23-43(51(78)72-46(33-38-19-9-8-10-20-38)56(83)74-32-18-27-48(74)54(81)67-36)69-52(79)45(34-39-35-66-41-22-13-12-21-40(39)41)71-50(77)42(68-37(2)75)24-15-29-64-57(59)60/h8-10,12-13,19-22,35-36,42-48,66H,3-7,11,14-18,23-34H2,1-2H3,(H,63,80)(H,67,81)(H,68,75)(H,69,79)(H,70,76)(H,71,77)(H,72,78)(H4,59,60,64)(H4,61,62,65)/t36-,42-,43-,44-,45-,46-,47-,48-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	43	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to menin (unknown origin) after 60 mins by fluorescence polarization assay				J Med Chem 56: 1113-23 (2013) Article DOI: 10.1021/jm3015298 BindingDB Entry DOI: 10.7270/Q22B91XM
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516560 (CHEMBL4592512 | US10899738, Cpd. No 132) Show SMILES CS(=O)(=O)c1ccc(cc1)N1CC(CN2CCC(CC2)C2(NCCc3ccccc23)C2CCCC2)C1 Show InChI InChI=1S/C30H41N3O2S/c1-36(34,35)28-12-10-27(11-13-28)33-21-23(22-33)20-32-18-15-26(16-19-32)30(25-7-3-4-8-25)29-9-5-2-6-24(29)14-17-31-30/h2,5-6,9-13,23,25-26,31H,3-4,7-8,14-22H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50489228 (CHEMBL2314573) Show SMILES [H][C@@]12CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)C1(CCC1)NC(=O)[C@]1([H])CCCN1C(=O)[C@H](Cc1cccc(Cl)c1)NC(=O)[C@@H](N)CCCCCCCCNC2=O |r| Show InChI InChI=1S/C40H61ClN10O6/c41-27-13-7-12-26(24-27)25-30-37(56)51-23-10-17-32(51)35(54)49-40(18-11-19-40)38(57)48-29(15-8-21-46-39(43)44)36(55)50-22-9-16-31(50)34(53)45-20-6-4-2-1-3-5-14-28(42)33(52)47-30/h7,12-13,24,28-32H,1-6,8-11,14-23,25,42H2,(H,45,53)(H,47,52)(H,48,57)(H,49,54)(H4,43,44,46)/t28-,29-,30-,31-,32-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to menin (unknown origin) after 60 mins by fluorescence polarization assay				J Med Chem 56: 1113-23 (2013) Article DOI: 10.1021/jm3015298 BindingDB Entry DOI: 10.7270/Q22B91XM
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50489244 (CHEMBL2314568) Show SMILES [H][C@@]12CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)C1(CC1)NC(=O)[C@]1([H])CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCCCCCCNC2=O |r| Show InChI InChI=1S/C39H60N10O6/c40-27-15-8-3-1-2-4-9-21-43-33(51)30-17-11-23-48(30)35(53)28(16-10-22-44-38(41)42)46-37(55)39(19-20-39)47-34(52)31-18-12-24-49(31)36(54)29(45-32(27)50)25-26-13-6-5-7-14-26/h5-7,13-14,27-31H,1-4,8-12,15-25,40H2,(H,43,51)(H,45,50)(H,46,55)(H,47,52)(H4,41,42,44)/t27-,28-,29-,30-,31-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	56	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to menin (unknown origin) after 60 mins by fluorescence polarization assay				J Med Chem 56: 1113-23 (2013) Article DOI: 10.1021/jm3015298 BindingDB Entry DOI: 10.7270/Q22B91XM
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50496346 (CHEMBL3126196) Show SMILES NC(C1CCCC1)(C1CCN(CCCOc2ccc(cc2)C#N)CC1)c1ccccc1 Show InChI InChI=1S/C27H35N3O/c28-21-22-11-13-26(14-12-22)31-20-6-17-30-18-15-25(16-19-30)27(29,24-9-4-5-10-24)23-7-2-1-3-8-23/h1-3,7-8,11-14,24-25H,4-6,9-10,15-20,29H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair				3D Structure (crystal)
Menin (Homo sapiens (Human))	BDBM50489246 (CHEMBL2315087) Show SMILES [H][C@@]12CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)C(C)(C)NC(=O)[C@]1([H])CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCCCCCCNC2=O |r| Show InChI InChI=1S/C39H62N10O6/c1-39(2)37(55)46-28(18-12-22-44-38(41)42)35(53)48-23-13-19-30(48)33(51)43-21-11-6-4-3-5-10-17-27(40)32(50)45-29(25-26-15-8-7-9-16-26)36(54)49-24-14-20-31(49)34(52)47-39/h7-9,15-16,27-31H,3-6,10-14,17-25,40H2,1-2H3,(H,43,51)(H,45,50)(H,46,55)(H,47,52)(H4,41,42,44)/t27-,28-,29-,30-,31-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	67	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to menin (unknown origin) after 60 mins by fluorescence polarization assay				J Med Chem 56: 1113-23 (2013) Article DOI: 10.1021/jm3015298 BindingDB Entry DOI: 10.7270/Q22B91XM
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50489238 (CHEMBL2314824) Show SMILES C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(N)=O |r| Show InChI InChI=1S/C53H79N19O9/c1-30(44(75)68-38(19-10-24-63-53(59)60)49(80)71-25-11-20-41(71)43(54)74)65-48(79)42-21-12-26-72(42)50(81)40(27-32-13-4-3-5-14-32)70-46(77)37(18-9-23-62-52(57)58)67-47(78)39(28-33-29-64-35-16-7-6-15-34(33)35)69-45(76)36(66-31(2)73)17-8-22-61-51(55)56/h3-7,13-16,29-30,36-42,64H,8-12,17-28H2,1-2H3,(H2,54,74)(H,65,79)(H,66,73)(H,67,78)(H,68,75)(H,69,76)(H,70,77)(H4,55,56,61)(H4,57,58,62)(H4,59,60,63)/t30-,36-,37-,38-,39-,40-,41-,42-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	71	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to menin (unknown origin) after 60 mins by fluorescence polarization assay				J Med Chem 56: 1113-23 (2013) Article DOI: 10.1021/jm3015298 BindingDB Entry DOI: 10.7270/Q22B91XM
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50454123 (CHEMBL4216333) Show SMILES NCC(CCN1CCC(=CC1)c1ccc(Cl)cc1)(C1CCCC1)c1ccccc1 |c:8| Show InChI InChI=1S/C26H33ClN2/c27-25-12-10-21(11-13-25)22-14-17-29(18-15-22)19-16-26(20-28,24-8-4-5-9-24)23-6-2-1-3-7-23/h1-3,6-7,10-14,24H,4-5,8-9,15-20,28H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Displacement of FITC-MBM1 from full length human menin measured after 2 hrs by fluorescence polarization assay				Bioorg Med Chem 26: 356-365 (2018) Article DOI: 10.1016/j.bmc.2017.11.045 BindingDB Entry DOI: 10.7270/Q2SQ92ZS
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50489224 (CHEMBL2314818) Show SMILES [H][C@@]12CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)C1(CCC1)NC(=O)[C@]1([H])CCCN1C(=O)[C@H](Cc1ccc(F)cc1)NC(=O)[C@@H](N)CCCCCCCCNC2=O |r| Show InChI InChI=1S/C40H61FN10O6/c41-27-17-15-26(16-18-27)25-30-37(56)51-24-9-14-32(51)35(54)49-40(19-10-20-40)38(57)48-29(12-7-22-46-39(43)44)36(55)50-23-8-13-31(50)34(53)45-21-6-4-2-1-3-5-11-28(42)33(52)47-30/h15-18,28-32H,1-14,19-25,42H2,(H,45,53)(H,47,52)(H,48,57)(H,49,54)(H4,43,44,46)/t28-,29-,30-,31-,32-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	123	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to menin (unknown origin) after 60 mins by fluorescence polarization assay				J Med Chem 56: 1113-23 (2013) Article DOI: 10.1021/jm3015298 BindingDB Entry DOI: 10.7270/Q22B91XM
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50489235 (CHEMBL2314831) Show SMILES [H][C@@]12CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@]1([H])CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCCCNC2=O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O |r| Show InChI InChI=1S/C54H78N16O9/c1-32-45(72)66-40(21-12-26-61-54(57)58)51(78)69-27-13-22-43(69)49(76)59-24-10-4-7-19-39(47(74)68-42(29-34-15-5-3-6-16-34)52(79)70-28-14-23-44(70)50(77)63-32)65-48(75)41(30-35-31-62-37-18-9-8-17-36(35)37)67-46(73)38(64-33(2)71)20-11-25-60-53(55)56/h3,5-6,8-9,15-18,31-32,38-44,62H,4,7,10-14,19-30H2,1-2H3,(H,59,76)(H,63,77)(H,64,71)(H,65,75)(H,66,72)(H,67,73)(H,68,74)(H4,55,56,60)(H4,57,58,61)/t32-,38-,39-,40-,41-,42-,43-,44-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	136	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to menin (unknown origin) after 60 mins by fluorescence polarization assay				J Med Chem 56: 1113-23 (2013) Article DOI: 10.1021/jm3015298 BindingDB Entry DOI: 10.7270/Q22B91XM
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50489233 (CHEMBL2315084) Show SMILES [H][C@@]12CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@]1([H])CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCCCCCCNC2=O |r| Show InChI InChI=1S/C38H60N10O6/c1-25-32(49)45-28(17-11-21-43-38(40)41)36(53)47-22-12-18-30(47)34(51)42-20-10-5-3-2-4-9-16-27(39)33(50)46-29(24-26-14-7-6-8-15-26)37(54)48-23-13-19-31(48)35(52)44-25/h6-8,14-15,25,27-31H,2-5,9-13,16-24,39H2,1H3,(H,42,51)(H,44,52)(H,45,49)(H,46,50)(H4,40,41,43)/t25-,27-,28-,29-,30-,31-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	197	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to menin (unknown origin) after 60 mins by fluorescence polarization assay				J Med Chem 56: 1113-23 (2013) Article DOI: 10.1021/jm3015298 BindingDB Entry DOI: 10.7270/Q22B91XM
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516557 (CHEMBL4537683 | US10899738, Cpd. No 55) Show SMILES N#Cc1ccc(cc1)N1CCC(CC1)N1CCC(CC1)C1(NCCc2ccccc12)C1CCCC1 Show InChI InChI=1S/C31H40N4/c32-23-24-9-11-28(12-10-24)35-21-16-29(17-22-35)34-19-14-27(15-20-34)31(26-6-2-3-7-26)30-8-4-1-5-25(30)13-18-33-31/h1,4-5,8-12,26-27,29,33H,2-3,6-7,13-22H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	207	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50489249 (CHEMBL2314826) Show SMILES C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(N)=O |r| Show InChI InChI=1S/C47H67N15O8/c1-27(40(65)59-34(17-9-21-54-47(51)52)44(69)61-22-10-18-37(61)39(48)64)56-43(68)38-19-11-23-62(38)45(70)36(24-29-12-4-3-5-13-29)60-41(66)33(16-8-20-53-46(49)50)58-42(67)35(57-28(2)63)25-30-26-55-32-15-7-6-14-31(30)32/h3-7,12-15,26-27,33-38,55H,8-11,16-25H2,1-2H3,(H2,48,64)(H,56,68)(H,57,63)(H,58,67)(H,59,65)(H,60,66)(H4,49,50,53)(H4,51,52,54)/t27-,33-,34-,35-,36-,37-,38-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	311	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to menin (unknown origin) after 60 mins by fluorescence polarization assay				J Med Chem 56: 1113-23 (2013) Article DOI: 10.1021/jm3015298 BindingDB Entry DOI: 10.7270/Q22B91XM
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50489242 (CHEMBL2314575) Show SMILES [H][C@@]12CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)C1(CCC1)NC(=O)[C@]1([H])CCCN1C(=O)[C@H](Cc1cccc(C)c1)NC(=O)[C@@H](N)CCCCCCCCNC2=O |r| Show InChI InChI=1S/C41H64N10O6/c1-27-13-8-14-28(25-27)26-31-38(56)51-24-11-18-33(51)36(54)49-41(19-12-20-41)39(57)48-30(16-9-22-46-40(43)44)37(55)50-23-10-17-32(50)35(53)45-21-7-5-3-2-4-6-15-29(42)34(52)47-31/h8,13-14,25,29-33H,2-7,9-12,15-24,26,42H2,1H3,(H,45,53)(H,47,52)(H,48,57)(H,49,54)(H4,43,44,46)/t29-,30-,31-,32-,33-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	332	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Binding affinity to menin (unknown origin) after 60 mins by fluorescence polarization assay				J Med Chem 56: 1113-23 (2013) Article DOI: 10.1021/jm3015298 BindingDB Entry DOI: 10.7270/Q22B91XM
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516580 (CHEMBL4453547) Show SMILES [H][C@@]1(CCC[C@@H]1OC(=O)CCC)[C@@](C#N)(C1CCN(CC2CN(C2)c2ccc(cc2)C#N)CC1)c1ccccc1 |r| Show InChI InChI=1S/C33H40N4O2/c1-2-7-32(38)39-31-11-6-10-30(31)33(24-35,27-8-4-3-5-9-27)28-16-18-36(19-17-28)21-26-22-37(23-26)29-14-12-25(20-34)13-15-29/h3-5,8-9,12-15,26,28,30-31H,2,6-7,10-11,16-19,21-23H2,1H3/t30-,31-,33+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516573 (CHEMBL4448156 | US10899738, Cpd. No 53) Show SMILES O=S(=O)(c1ccncc1)c1ccc(cc1)N1CC(CN2CCC(CC2)C2(CN(Cc3ccncc3)Cc3ccccc23)C2CCCC2)C1 Show InChI InChI=1S/C40H47N5O2S/c46-48(47,38-15-21-42-22-16-38)37-11-9-36(10-12-37)45-27-32(28-45)26-43-23-17-35(18-24-43)40(34-6-2-3-7-34)30-44(25-31-13-19-41-20-14-31)29-33-5-1-4-8-39(33)40/h1,4-5,8-16,19-22,32,34-35H,2-3,6-7,17-18,23-30H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	361	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair

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