The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
28692292 |
73 |
Discovery of Potent and Selective Inhibitors of Cdc2-Like Kinase 1 (CLK1) as a New Class of Autophagy Inducers.![EBI](/images/logo_chembl.png) |
Sichuan University and Collaborative Innovation Center For Biotherapy |
26762835 |
342 |
Discovery of 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one (7ao) as a potent selective inhibitor of Polo like kinase 2 (PLK2).![EBI](/images/logo_chembl.png) |
Icahn School of Medicine At Mount Sinai |
26275681 |
15 |
Discovery and structure of a new inhibitor scaffold of the autophagy initiating kinase ULK1.![EBI](/images/logo_chembl.png) |
University of California |
21413800 |
56 |
A one-pot synthesis and biological activity of ageladine A and analogues.![EBI](/images/logo_chembl.png) |
Macquarie University |
22037378 |
31824 |
Comprehensive analysis of kinase inhibitor selectivity.![EBI](/images/logo_chembl.png) |
Ambit Biosciences |
19654408 |
2521 |
AC220 is a uniquely potent and selective inhibitor of FLT3 for the treatment of acute myeloid leukemia (AML).![EBI](/images/logo_chembl.png) |
Ambit Biosciences |
31859507 |
212 |
Discovery of BAY-985, a Highly Selective TBK1/IKK? Inhibitor.![EBI](/images/logo_chembl.png) |
Bayer |
31693351 |
473 |
Discovery of 4![EBI](/images/logo_chembl.png) |
TBA |
30384048 |
365 |
ASR352, A potent anticancer agent: Synthesis, preliminary SAR, and biological activities against colorectal cancer bulk, 5-fluorouracil/oxaliplatin resistant and stem cells.![EBI](/images/logo_chembl.png) |
University of Florida |
31526603 |
379 |
Structure-based rational design of staurosporine-based fluorescent probe with broad-ranging kinase affinity for kinase panel application.![EBI](/images/logo_chembl.png) |
Takeda Pharmaceutical |
29211480 |
64 |
Design of Small Molecule Autophagy Modulators: A Promising Druggable Strategy.![EBI](/images/logo_chembl.png) |
China Pharmaceutical University |
29561612 |
5 |
Small-Molecule Activator of UNC-51-Like Kinase 1 (ULK1) That Induces Cytoprotective Autophagy for Parkinson's Disease Treatment.![EBI](/images/logo_chembl.png) |
Sichuan University |
29259744 |
30 |
HTS and Structure Based Optimization of Indazole-Derived ULK1 Inhibitors.![EBI](/images/logo_chembl.png) |
The Scripps Research Institute |
29509411 |
8 |
UNC-51-like Kinase 1: From an Autophagic Initiator to Multifunctional Drug Target.![EBI](/images/logo_chembl.png) |
Sichuan Universitt China Hospital |