The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
26303893 |
93 |
A novel series of indazole-/indole-based glucagon receptor antagonists. |
Merck Research Laboratories |
24881566 |
140 |
Identification of diarylsulfonamides as agonists of the free fatty acid receptor 4 (FFA4/GPR120). |
Glaxosmithkline |
24527772 |
262 |
The discovery of N-((2H-tetrazol-5-yl)methyl)-4-((R)-1-((5r,8R)-8-(tert-butyl)-3-(3,5-dichlorophenyl)-2-oxo-1,4-diazaspiro[4.5]dec-3-en-1-yl)-4,4-dimethylpentyl)benzamide (SCH 900822): a potent and selective glucagon receptor antagonist. |
Merck Research Laboratories |
22708876 |
106 |
Discovery of a novel glucagon receptor antagonist N-[(4-{(1S)-1-[3-(3, 5-dichlorophenyl)-5-(6-methoxynaphthalen-2-yl)-1H-pyrazol-1-yl]ethyl}phenyl)carbonyl]-ß-alanine (MK-0893) for the treatment of type II diabetes. |
Merck Research Laboratories |
19702274 |
31 |
Eleven amino acid glucagon-like peptide-1 receptor agonists with antidiabetic activity. |
Bristol-Myers Squibb |
22119466 |
38 |
A novel series of glucagon receptor antagonists with reduced molecular weight and lipophilicity. |
Pfizer |
22030028 |
55 |
Discovery of N-aryl-2-acylindole human glucagon receptor antagonists. |
Merck Research Laboratories |
22001094 |
78 |
Discovery of cyclic guanidines as potent, orally active, human glucagon receptor antagonists. |
Merck Research Laboratories |
21147532 |
82 |
Discovery of novel, potent, selective, and orally active human glucagon receptor antagonists containing a pyrazole core. |
Merck Research Laboratories |
18707090 |
68 |
Novel glucagon receptor antagonists with improved selectivity over the glucose-dependent insulinotropic polypeptide receptor. |
Novo Nordisk |
17126016 |
69 |
Design and synthesis of conformationally constrained tri-substituted ureas as potent antagonists of the human glucagon receptor. |
Merck Research Laboratories |
16102966 |
55 |
Discovery of novel, potent, and orally active spiro-urea human glucagon receptor antagonists. |
Merck Research Laboratories |
29153547 |
50 |
Optimization of peptide-based polyagonists for treatment of diabetes and obesity. |
Novo Nordisk Research Center Indianapolis |
29879354 |
54 |
Dual Glucagon-like Peptide 1 (GLP-1)/Glucagon Receptor Agonists Specifically Optimized for Multidose Formulations. |
Sanofi-Aventis Deutschland |
21108268 |
67 |
Biological evaluation and structural determinants of p38α mitogen-activated-protein kinase and c-Jun-N-terminal kinase 3 inhibition by flavonoids. |
Eberhard Karls University of Tuebingen |