The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
28274633 |
2 |
Discovery of a 2'-fluoro-2'-C-methyl C-nucleotide HCV polymerase inhibitor and a phosphoramidate prodrug with favorable properties. |
Gilead Sciences |
28124907 |
3 |
Discovery and Synthesis of a Phosphoramidate Prodrug of a Pyrrolo[2,1-f][triazin-4-amino] Adenine C-Nucleoside (GS-5734) for the Treatment of Ebola and Emerging Viruses. |
Gilead Sciences |
24944743 |
3 |
Discovery and Synthesis of C-Nucleosides as Potential New Anti-HCV Agents. |
Biota Scientific Management |
23968551 |
55 |
New nucleotide-competitive non-nucleoside inhibitors of terminal deoxynucleotidyl transferase: discovery, characterization, and crystal structure in complex with the target. |
Sapienza University of Rome |
23713606 |
116 |
8-Benzamidochromen-4-one-2-carboxylic acids: potent and selective agonists for the orphan G protein-coupled receptor GPR35. |
University of Bonn |
21561086 |
21 |
Selective inhibition of the tumor marker aldo-keto reductase family member 1B10 by oleanolic acid. |
Gifu Pharmaceutical University |
18811136 |
4 |
Alpha,beta-methylene-2'-deoxynucleoside 5'-triphosphates as noncleavable substrates for DNA polymerases: isolation, characterization, and stability studies of novel 2'-deoxycyclonucleosides, 3,5'-cyclo-dG, and 2,5'-cyclo-dT. |
University of Rhode Island |
14640519 |
5 |
A new acylated oleanane triterpenoid from Couepia polyandra that inhibits the lyase activity of DNA polymerase beta. |
Virginia Polytechnic Institute and State University |
8864237 |
4 |
Specific inhibition of human immunodeficiency virus type 1 reverse transcriptase mediated by soulattrolide, a coumarin isolated from the latex of calophyllum teysmannii. |
Chulalongkorn University |
18343122 |
8 |
Inhibitors of DNA polymerase beta: activity and mechanism. |
University of Virginia |
9622545 |
41 |
Newly synthesized L-enantiomers of 3'-fluoro-modified beta-2'-deoxyribonucleoside 5'-triphosphates inhibit hepatitis B DNA polymerases but not the five cellular DNA polymerases alpha, beta, gamma, delta, and epsilon nor HIV-1 reverse transcriptase. |
Max-Delbr�Ck-Centrum F�R Molekulare Medizin |
18852280 |
8 |
1,5-benzodiazepines, a novel class of hepatitis C virus polymerase nonnucleoside inhibitors. |
Tibotec |
19398642 |
10 |
GS-9191 is a novel topical prodrug of the nucleotide analog 9-(2-phosphonylmethoxyethyl)guanine with antiproliferative activity and possible utility in the treatment of human papillomavirus lesions. |
Gilead Sciences |
20516278 |
10 |
PSI-7851, a pronucleotide of beta-D-2'-deoxy-2'-fluoro-2'-C-methyluridine monophosphate, is a potent and pan-genotype inhibitor of hepatitis C virus replication. |
Pharmasset |
20014868 |
6 |
N-sulfonylanthranilic acid derivatives as allosteric inhibitors of dengue viral RNA-dependent RNA polymerase. |
Novartis Institute For Tropical Diseases |
1705574 |
2 |
Differential Inhibition of Reverse Transcriptase and Various DNA Polymerases by Digallic Acid and Its Derivatives |
TBA |
7561895 |
4 |
Mechanistic Evaluation of New Plant-Derived Compounds That Inhibit HIV-1 Reverse Transcriptase |
TBA |
18364258 |
1 |
Hymenoic acid, a novel specific inhibitor of human DNA polymerase lambda from a fungus of Hymenochaetaceae sp. |
Kobe Gakuin University |
16038535 |
5 |
Acylphloroglucinol derivatives from Mahurea palustris. |
National Center For Scientific Research (Cnrs)-Pierre Fabre |
15497946 |
2 |
Marine sesquiterpenoids that inhibit the lyase activity of DNA polymerase beta. |
Virginia Polytechnic Institute and State University |
15217274 |
13 |
New neolignans that inhibit DNA polymerase beta lyase. |
Virginia Polytechnic Institute and State University |
15165161 |
5 |
A new ursane triterpene from Monochaetum vulcanicum that inhibits DNA polymerase beta lyase. |
Virginia Polytechnic Institute and State University |
16854079 |
57 |
Benzimidazole derivatives bearing substituted biphenyls as hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitors: structure-activity relationship studies and identification of a potent and highly selective inhibitor JTK-109. |
Central Pharmaceutical Research Institute |
16722622 |
24 |
Discovery of proline sulfonamides as potent and selective hepatitis C virus NS5b polymerase inhibitors. Evidence for a new NS5b polymerase binding site. |
Wyeth Research |
16563761 |
48 |
Synthetic analogues of the manzamenones and plakoridines which inhibit DNA polymerase. |
The University of Manchester |
16455252 |
72 |
Benzimidazole inhibitors of hepatitis C virus NS5B polymerase: identification of 2-[(4-diarylmethoxy)phenyl]-benzimidazole. |
Central Pharmaceutical Research Institute |
16451063 |
139 |
3-(1,1-dioxo-2H-(1,2,4)-benzothiadiazin-3-yl)-4-hydroxy-2(1H)-quinolinones, potent inhibitors of hepatitis C virus RNA-dependent RNA polymerase. |
Glaxosmithkline |
15588095 |
1 |
Discovery of pyrano[3,4-b]indoles as potent and selective HCV NS5B polymerase inhibitors. |
Wyeth Research |
15261274 |
28 |
Identification of [(naphthalene-1-carbonyl)-amino]-acetic acid derivatives as nonnucleoside inhibitors of HCV NS5B RNA dependent RNA polymerase. |
Wyeth Research |
30653317 |
104 |
Discovery of a Series of 2'-?-Fluoro,2'-?-bromo-ribonucleosides and Their Phosphoramidate Prodrugs as Potent Pan-Genotypic Inhibitors of Hepatitis C Virus. |
Emory University School of Medicine |
28633899 |
8 |
Discovery of BMS-961955, an allosteric inhibitor of the hepatitis C virus NS5B polymerase. |
Bristol-Myers Squibb Research and Development |
28835346 |
3 |
The discovery of IDX21437: Design, synthesis and antiviral evaluation of 2'-?-chloro-2'-?-C-methyl branched uridine pronucleotides as potent liver-targeted HCV polymerase inhibitors. |
Idenix An Msd |
28595015 |
14 |
2'-Chloro,2'-fluoro Ribonucleotide Prodrugs with Potent Pan-genotypic Activity against Hepatitis C Virus Replication in Culture. |
Emory University |