The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
25782742 |
76 |
trans-(3S,4S)-Disubstituted pyrrolidines as inhibitors of the human aspartyl protease renin. Part I: prime site exploration using an amino linker. |
Novartis Pharma |
25754490 |
44 |
trans-3,4-Disubstituted pyrrolidines as inhibitors of the human aspartyl protease renin. Part II: prime site exploration using an oxygen linker. |
Novartis Pharma |
25050166 |
58 |
Structure-based design of substituted piperidines as a new class of highly efficacious oral direct Renin inhibitors. |
Novartis Institutes For Biomedical Research |
9632367 |
10 |
Auxiliary agents for the peroral administration of peptide and protein drugs: synthesis and evaluation of novel pepstatin analogues. |
Institute of Pharmaceutical Chemistry |
1527792 |
55 |
Specific inhibition of HIV-1 protease by boronated porphyrins. |
University of California |
1635057 |
48 |
Structure-activity relationships of a series of 2-amino-4-thiazole-containing renin inhibitors. |
Parke-Davis Pharmaceutical Research Division of Warner-Lambert |
11806706 |
7 |
Designing non-peptide peptidomimetics in the 21st century: inhibitors targeting conformational ensembles. |
University of Wisconsin-Madison |
8410992 |
35 |
Renin inhibitors containing a pyridyl amino diol derived C-terminus. |
Hoechst |
8410973 |
75 |
Specificity in the binding of inhibitors to the active site of human/primate aspartic proteinases: analysis of P2-P1-P1'-P2' variation. |
University of Florida |
6767029 |
14 |
Synthesis of analogues of the carboxyl protease inhibitor pepstatin. Effects of structure on inhibition of pepsin and renin. |
TBA |
3126296 |
43 |
Inhibition of porcine pepsin by two substrate analogues containing statine. The effect of histidine at the P2 subsite on the inhibition of aspartic proteinases. |
University of Wisconsin |
1738148 |
16 |
Renin inhibitory pentols showing improved enteral bioavailability. |
Hoechst |