The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
3637247 |
6 |
Peptidyl carbamates incorporating amino acid isosteres as novel elastase inhibitors. |
TBA |
2566685 |
47 |
Inhibition of aminopeptidases by peptides containing ketomethylene and hydroxyethylene amide bond replacements. |
University of Wisconsin-Madison |
11055335 |
27 |
Highly potent and selective peptide-based inhibitors of the hepatitis C virus serine protease: towards smaller inhibitors. |
Boehringer Ingelheim Pharmaceuticals |
10360758 |
10 |
Metallopeptide approach to the design of biologically active ligands: design of specific human neutrophil elastase inhibitors. |
Palatin Technologies |
| 45 |
A comparative SAR and computer modeling study of benzisothiazolone, mechanism-based inhibitors with porcine pancreatic and human leukocyte elastase |
TBA |
| 27 |
Synthesis and porcine pancreatic elastase inhibitory evaluation of 6α-(sulfonyl)oxy-and 6α-chloropenicillanate sulfone esters and 3α-(acyloxy)methyl-6α-chloropenam sulfones |
TBA |
| 46 |
1,3-Oxazino[4,5-b]indole-2,4-(1H,9H)-diones and 5,6-dimethylpyrrolo-[2,3-d]-1,3-oxazin-2,4-(1H,7H)-diones as serine protease inhi... |
TBA |
| 30 |
Enantioselective synthesis and antielastase activity of 1,3,4-trisubstituted and 3,4-disubstituted β-lactam antibiotics |
TBA |
12565935 |
5 |
Synthesis and evaluation of delta-lactams (piperazones) as elastase inhibitors. |
The Oxford Centre For Molecular Sciences and The Dyson Perrins Laboratory |
10866385 |
13 |
Mass spectrometry reveals elastase inhibitors from the reactive centre loop of alpha1-antitrypsin. |
The Oxford Centre For Molecular Sciences |
10698435 |
150 |
Structure-activity relationship studies of chloromethyl ketone derivatives for selective human chymase inhibitors. |
Kyoto Pharmaceutical University |
10091694 |
90 |
Symmetrical anhydride-type serine protease inhibitors: structure-activity relationship studies of human chymase inhibitors. |
Nippon Steel |
9925737 |
57 |
N-[2,2-dimethyl-3-(N-(4-cyanobenzoyl)amino)nonanoyl]-L-phenylalanine ethyl ester as a stable ester-type inhibitor of chymotrypsin-like serine proteases: structural requirements for potent inhibition of alpha-chymotrypsin. |
Nippon Steel |
9873610 |
48 |
Studies on the C-terminal of hexapeptide inhibitors of the hepatitis C virus serine protease. |
Boehringer Ingelheim (Canada) |
9871780 |
85 |
Inhibition of human cytomegalovirus protease N(o) with monocyclic beta-lactams. |
Boehringer Ingelheim (Canada) |
9406601 |
109 |
Peptidomimetic inhibitors of the human cytomegalovirus protease. |
Boehringer Ingelheim |
9379436 |
46 |
Orally active trifluoromethyl ketone inhibitors of human leukocyte elastase. |
Zeneca Pharmaceuticals |
9341917 |
69 |
7-alkylidenecephalosporin esters as inhibitors of human leukocyte elastase. |
Southern Methodist University |
9191969 |
31 |
Dual inhibition of human leukocyte elastase and lipid peroxidation: in vitro and in vivo activities of azabicyclo[2.2.2]octane and perhydroindole derivatives. |
Institut De Recherche Servier |
7932558 |
30 |
Nonpeptidic inhibitors of human leukocyte elastase. 2. Design, synthesis, and in vitro activity of a series of 3-amino-6-arylopyridin-2-one trifluoromethyl ketones. |
Zeneca Pharmaceuticals Group |
7739010 |
118 |
Characterization of a class of peptide boronates with neutral P1 side chains as highly selective inhibitors of thrombin. |
Thrombosis Research Institute |
7562931 |
41 |
Peptidyl alpha-ketoheterocyclic inhibitors of human neutrophil elastase. 3. In vitro and in vivo potency of a series of peptidyl alpha-ketobenzoxazoles. |
Zeneca Pharmaceuticals |
18693761 |
4 |
Kempopeptins A and B, serine protease inhibitors with different selectivity profiles from a marine cyanobacterium, Lyngbya sp. |
University of Florida |
3844034 |
13 |
Amino acid derived latent isocyanates: irreversible inactivation of porcine pancreatic elastase and human leukocyte elastase. |
TBA |
2391691 |
55 |
Inhibition of human leukocyte elastase. 1. Inhibition by C-7-substituted cephalosporin tert-butyl esters. |
Merck Sharp and Dohme Research Laboratories |
2296031 |
48 |
Synthesis of peptidyl fluoromethyl ketones and peptidyl alpha-keto esters as inhibitors of porcine pancreatic elastase, human neutrophil elastase, and rat and human neutrophil cathepsin G. |
Merrell Dow Research Institute |