The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
26340601 |
54 |
Recent Update on Human Lactate Dehydrogenase Enzyme 5 (hLDH5) Inhibitors: A Promising Approach for Cancer Chemotherapy. |
National Cancer Institute-Cro |
26114812 |
26 |
Identification of N-acylhydrazone derivatives as novel lactate dehydrogenase A inhibitors. |
University of Bologna |
25288186 |
20 |
An update on therapeutic opportunities offered by cancer glycolytic metabolism. |
Universit£ |
25466195 |
41 |
Optimization of 5-(2,6-dichlorophenyl)-3-hydroxy-2-mercaptocyclohex-2-enones as potent inhibitors of human lactate dehydrogenase. |
Genentech |
25037916 |
185 |
Identification of substituted 3-hydroxy-2-mercaptocyclohex-2-enones as potent inhibitors of human lactate dehydrogenase. |
Genentech |
25467161 |
43 |
Identification of 3,6-disubstituted dihydropyrones as inhibitors of human lactate dehydrogenase. |
Genentech |
24012183 |
91 |
Identification of 2-amino-5-aryl-pyrazines as inhibitors of human lactate dehydrogenase. |
Genentech |
23628333 |
69 |
Identification of substituted 2-thio-6-oxo-1,6-dihydropyrimidines as inhibitors of human lactate dehydrogenase. |
Genentech |
23302067 |
29 |
Fragment growing and linking lead to novel nanomolar lactate dehydrogenase inhibitors. |
Ariad Pharmaceuticals |
8308865 |
9 |
CNAD: a potent and specific inhibitor of alcohol dehydrogenase. |
University of Rochester Medical Center |
21332213 |
10 |
Discovery of N-hydroxyindole-based inhibitors of human lactate dehydrogenase isoform A (LDH-A) as starvation agents against cancer cells. |
Universita` Di Pisa |
31879209 |
6 |
Identification of human lactate dehydrogenase A inhibitors with anti-osteosarcoma activity through cell-based phenotypic screening. |
Jilin University China-Japan Union Hospital |
27406795 |
6 |
Discovery of 2-((3-cyanopyridin-2-yl)thio)acetamides as human lactate dehydrogenase A inhibitors to reduce the growth of MG-63 osteosarcoma cells: Virtual screening and biological validation. |
Heilongjiang Province Hospital |
31345633 |
3 |
Discovery of human lactate dehydrogenase 5 inhibitors (hLDH5) with anti-lung cancer activity through an in silico method and biological validation. |
The 5Th Affiliated Hospital of Shenzhen University Health Science Center |
27774125 |
82 |
Cell Active Hydroxylactam Inhibitors of Human Lactate Dehydrogenase with Oral Bioavailability in Mice. |
Genentech |
32250117 |
27 |
Interrogating the Lactate Dehydrogenase Tetramerization Site Using (Stapled) Peptides. |
Universit£ |
31129449 |
24 |
Development of novel human lactate dehydrogenase A inhibitors: High-throughput screening, synthesis, and biological evaluations. |
Hubei University of Medicine |
30300845 |
43 |
1-(2-Hydroxybenzoyl)-thiosemicarbazides are promising antimicrobial agents targeting d-alanine-d-alanine ligase in bacterio. |
Universit£ |
31327531 |
35 |
Inhibition of 3-phosphoglycerate dehydrogenase (PHGDH) by indole amides abrogates de novo serine synthesis in cancer cells. |
Meyer Cancer Center |
9748363 |
30 |
Selective inhibitors of human lactate dehydrogenases and lactate dehydrogenase from the malarial parasite Plasmodium falciparum. |
University of New Mexico School of Medicine |
26597536 |
7 |
Identification of a potent inhibitor targeting human lactate dehydrogenase A and its metabolic modulation for cancer cell line. |
Chongqing University |
29541354 |
6 |
Thiazole Derivatives as Inhibitors for the Treatment of Cancer Cells Resistant. |
Usona Institute |
28692289 |
12 |
Constituents of Polygala flavescens ssp. flavescens and Their Activity as Inhibitors of Human Lactate Dehydrogenase. |
Universit£ |
29861142 |
3 |
Computer-aided discovery and biological characterization of human lactate dehydrogenase 5 inhibitors with anti-osteosarcoma activity. |
Capital Medical University |
29120638 |
216 |
Discovery and Optimization of Potent, Cell-Active Pyrazole-Based Inhibitors of Lactate Dehydrogenase (LDH). |
National Center For Advancing Translational Sciences |
27082157 |
2 |
Dissecting the Multiple Roles of PqsE in Pseudomonas aeruginosa Virulence by Discovery of Small Tool Compounds. |
Helmholtz-Institute For Pharmaceutical Research Saarland |