Found 91 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441138
(CHEMBL2430727)Show SMILES C[C@@H](Nc1nc(cnc1N)-c1cc(ccc1C)C(O)=O)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C20H19ClN4O2/c1-11-3-4-14(20(26)27)9-16(11)17-10-23-18(22)19(25-17)24-12(2)13-5-7-15(21)8-6-13/h3-10,12H,1-2H3,(H2,22,23)(H,24,25)(H,26,27)/t12-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441115
(CHEMBL2430713)Show SMILES C[C@@H](Nc1nc(cnc1N)-c1cccc(c1)C(O)=O)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C19H17ClN4O2/c1-11(12-5-7-15(20)8-6-12)23-18-17(21)22-10-16(24-18)13-3-2-4-14(9-13)19(25)26/h2-11H,1H3,(H2,21,22)(H,23,24)(H,25,26)/t11-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441119
(CHEMBL2430733)Show SMILES CC(C)c1ccc(cc1-c1cnc(N)c(N[C@H](C)c2ccccc2)n1)C(O)=O |r| Show InChI InChI=1S/C22H24N4O2/c1-13(2)17-10-9-16(22(27)28)11-18(17)19-12-24-20(23)21(26-19)25-14(3)15-7-5-4-6-8-15/h4-14H,1-3H3,(H2,23,24)(H,25,26)(H,27,28)/t14-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441120
(CHEMBL2430732)Show SMILES C[C@@H](Nc1nc(cnc1N)-c1cc(ccc1C)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C20H20N4O2/c1-12-8-9-15(20(25)26)10-16(12)17-11-22-18(21)19(24-17)23-13(2)14-6-4-3-5-7-14/h3-11,13H,1-2H3,(H2,21,22)(H,23,24)(H,25,26)/t13-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441117
(CHEMBL2430735)Show SMILES C[C@@H](Nc1nc(cnc1N)-c1cc(ccc1Cl)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C19H17ClN4O2/c1-11(12-5-3-2-4-6-12)23-18-17(21)22-10-16(24-18)14-9-13(19(25)26)7-8-15(14)20/h2-11H,1H3,(H2,21,22)(H,23,24)(H,25,26)/t11-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem
Similars
| PDB
Article
PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441118
(CHEMBL2430734)Show SMILES COc1ccc(cc1-c1cnc(N)c(N[C@H](C)c2ccccc2)n1)C(O)=O |r| Show InChI InChI=1S/C20H20N4O3/c1-12(13-6-4-3-5-7-13)23-19-18(21)22-11-16(24-19)15-10-14(20(25)26)8-9-17(15)27-2/h3-12H,1-2H3,(H2,21,22)(H,23,24)(H,25,26)/t12-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441113
(CHEMBL2430716)Show SMILES C[C@@H](Nc1nc(cnc1N)-c1cccc(c1)C(O)=O)C1CCCCC1 |r| Show InChI InChI=1S/C19H24N4O2/c1-12(13-6-3-2-4-7-13)22-18-17(20)21-11-16(23-18)14-8-5-9-15(10-14)19(24)25/h5,8-13H,2-4,6-7H2,1H3,(H2,20,21)(H,22,23)(H,24,25)/t12-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441121
(CHEMBL2430731)Show SMILES C[C@@H](Nc1nc(cnc1N)-c1cc(C)cc(c1)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C20H20N4O2/c1-12-8-15(10-16(9-12)20(25)26)17-11-22-18(21)19(24-17)23-13(2)14-6-4-3-5-7-14/h3-11,13H,1-2H3,(H2,21,22)(H,23,24)(H,25,26)/t13-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441132
(CHEMBL2430737)Show SMILES C[C@@H](Nc1nc(cnc1N)-c1cccc(c1)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C19H18N4O2/c1-12(13-6-3-2-4-7-13)22-18-17(20)21-11-16(23-18)14-8-5-9-15(10-14)19(24)25/h2-12H,1H3,(H2,20,21)(H,22,23)(H,24,25)/t12-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase B chain
(Homo sapiens (Human)) | BDBM50441115
(CHEMBL2430713)Show SMILES C[C@@H](Nc1nc(cnc1N)-c1cccc(c1)C(O)=O)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C19H17ClN4O2/c1-11(12-5-7-15(20)8-6-12)23-18-17(21)22-10-16(24-18)13-3-2-4-14(9-13)19(25)26/h2-11H,1H3,(H2,21,22)(H,23,24)(H,25,26)/t11-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHB (1 to 333) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase B chain
(Homo sapiens (Human)) | BDBM50441120
(CHEMBL2430732)Show SMILES C[C@@H](Nc1nc(cnc1N)-c1cc(ccc1C)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C20H20N4O2/c1-12-8-9-15(20(25)26)10-16(12)17-11-22-18(21)19(24-17)23-13(2)14-6-4-3-5-7-14/h3-11,13H,1-2H3,(H2,21,22)(H,23,24)(H,25,26)/t13-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHB (1 to 333) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase B chain
(Homo sapiens (Human)) | BDBM50441119
(CHEMBL2430733)Show SMILES CC(C)c1ccc(cc1-c1cnc(N)c(N[C@H](C)c2ccccc2)n1)C(O)=O |r| Show InChI InChI=1S/C22H24N4O2/c1-13(2)17-10-9-16(22(27)28)11-18(17)19-12-24-20(23)21(26-19)25-14(3)15-7-5-4-6-8-15/h4-14H,1-3H3,(H2,23,24)(H,25,26)(H,27,28)/t14-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHB (1 to 333) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase B chain
(Homo sapiens (Human)) | BDBM50441121
(CHEMBL2430731)Show SMILES C[C@@H](Nc1nc(cnc1N)-c1cc(C)cc(c1)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C20H20N4O2/c1-12-8-15(10-16(9-12)20(25)26)17-11-22-18(21)19(24-17)23-13(2)14-6-4-3-5-7-14/h3-11,13H,1-2H3,(H2,21,22)(H,23,24)(H,25,26)/t13-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHB (1 to 333) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase B chain
(Homo sapiens (Human)) | BDBM50441118
(CHEMBL2430734)Show SMILES COc1ccc(cc1-c1cnc(N)c(N[C@H](C)c2ccccc2)n1)C(O)=O |r| Show InChI InChI=1S/C20H20N4O3/c1-12(13-6-4-3-5-7-13)23-19-18(21)22-11-16(24-19)15-10-14(20(25)26)8-9-17(15)27-2/h3-12H,1-2H3,(H2,21,22)(H,23,24)(H,25,26)/t12-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHB (1 to 333) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase B chain
(Homo sapiens (Human)) | BDBM50441117
(CHEMBL2430735)Show SMILES C[C@@H](Nc1nc(cnc1N)-c1cc(ccc1Cl)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C19H17ClN4O2/c1-11(12-5-3-2-4-6-12)23-18-17(21)22-10-16(24-18)14-9-13(19(25)26)7-8-15(14)20/h2-11H,1H3,(H2,21,22)(H,23,24)(H,25,26)/t11-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHB (1 to 333) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441126
(CHEMBL2430744)Show SMILES C[C@@H](Nc1nc(cnc1N)-c1ccc(C(O)=O)c(O)c1)c1ccccc1 |r| Show InChI InChI=1S/C19H18N4O3/c1-11(12-5-3-2-4-6-12)22-18-17(20)21-10-15(23-18)13-7-8-14(19(25)26)16(24)9-13/h2-11,24H,1H3,(H2,20,21)(H,22,23)(H,25,26)/t11-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase B chain
(Homo sapiens (Human)) | BDBM50441132
(CHEMBL2430737)Show SMILES C[C@@H](Nc1nc(cnc1N)-c1cccc(c1)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C19H18N4O2/c1-12(13-6-3-2-4-7-13)22-18-17(20)21-11-16(23-18)14-8-5-9-15(10-14)19(24)25/h2-12H,1H3,(H2,20,21)(H,22,23)(H,24,25)/t12-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHB (1 to 333) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441116
(CHEMBL2430736)Show InChI InChI=1S/C18H16N4O2/c19-16-17(21-10-12-5-2-1-3-6-12)22-15(11-20-16)13-7-4-8-14(9-13)18(23)24/h1-9,11H,10H2,(H2,19,20)(H,21,22)(H,23,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441127
(CHEMBL2430743)Show SMILES C[C@@H](Nc1nc(cnc1N)-c1ccc(cc1)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C19H18N4O2/c1-12(13-5-3-2-4-6-13)22-18-17(20)21-11-16(23-18)14-7-9-15(10-8-14)19(24)25/h2-12H,1H3,(H2,20,21)(H,22,23)(H,24,25)/t12-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase B chain
(Homo sapiens (Human)) | BDBM50441125
(CHEMBL2430745)Show SMILES C[C@@H](Nc1nc(cnc1N)-n1cc(cn1)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C16H16N6O2/c1-10(11-5-3-2-4-6-11)20-15-14(17)18-8-13(21-15)22-9-12(7-19-22)16(23)24/h2-10H,1H3,(H2,17,18)(H,20,21)(H,23,24)/t10-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHB (1 to 333) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441122
(CHEMBL2430730)Show SMILES C[C@@H](Nc1nc(cnc1N)-c1ccc(C)c(c1)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C20H20N4O2/c1-12-8-9-15(10-16(12)20(25)26)17-11-22-18(21)19(24-17)23-13(2)14-6-4-3-5-7-14/h3-11,13H,1-2H3,(H2,21,22)(H,23,24)(H,25,26)/t13-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441125
(CHEMBL2430745)Show SMILES C[C@@H](Nc1nc(cnc1N)-n1cc(cn1)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C16H16N6O2/c1-10(11-5-3-2-4-6-11)20-15-14(17)18-8-13(21-15)22-9-12(7-19-22)16(23)24/h2-10H,1H3,(H2,17,18)(H,20,21)(H,23,24)/t10-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase B chain
(Homo sapiens (Human)) | BDBM50441126
(CHEMBL2430744)Show SMILES C[C@@H](Nc1nc(cnc1N)-c1ccc(C(O)=O)c(O)c1)c1ccccc1 |r| Show InChI InChI=1S/C19H18N4O3/c1-11(12-5-3-2-4-6-12)22-18-17(20)21-10-15(23-18)13-7-8-14(19(25)26)16(24)9-13/h2-11,24H,1H3,(H2,20,21)(H,22,23)(H,25,26)/t11-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHB (1 to 333) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase B chain
(Homo sapiens (Human)) | BDBM50441113
(CHEMBL2430716)Show SMILES C[C@@H](Nc1nc(cnc1N)-c1cccc(c1)C(O)=O)C1CCCCC1 |r| Show InChI InChI=1S/C19H24N4O2/c1-12(13-6-3-2-4-7-13)22-18-17(20)21-11-16(23-18)14-8-5-9-15(10-14)19(24)25/h5,8-13H,2-4,6-7H2,1H3,(H2,20,21)(H,22,23)(H,24,25)/t12-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHB (1 to 333) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase B chain
(Homo sapiens (Human)) | BDBM50441127
(CHEMBL2430743)Show SMILES C[C@@H](Nc1nc(cnc1N)-c1ccc(cc1)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C19H18N4O2/c1-12(13-5-3-2-4-6-13)22-18-17(20)21-11-16(23-18)14-7-9-15(10-8-14)19(24)25/h2-12H,1H3,(H2,20,21)(H,22,23)(H,24,25)/t12-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHB (1 to 333) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441111
(CHEMBL2430719)Show SMILES C[C@@H](Nc1cc(cnc1N)-c1cccc(c1)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C20H19N3O2/c1-13(14-6-3-2-4-7-14)23-18-11-17(12-22-19(18)21)15-8-5-9-16(10-15)20(24)25/h2-13,23H,1H3,(H2,21,22)(H,24,25)/t13-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441112
(CHEMBL2430717)Show InChI InChI=1S/C17H20N4O2/c18-15-16(20-9-11-4-1-2-5-11)21-14(10-19-15)12-6-3-7-13(8-12)17(22)23/h3,6-8,10-11H,1-2,4-5,9H2,(H2,18,19)(H,20,21)(H,22,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase B chain
(Homo sapiens (Human)) | BDBM50441110
(CHEMBL2430721)Show SMILES C[C@@H](Nc1cncc(n1)-c1cccc(c1)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C19H17N3O2/c1-13(14-6-3-2-4-7-14)21-18-12-20-11-17(22-18)15-8-5-9-16(10-15)19(23)24/h2-13H,1H3,(H,21,22)(H,23,24)/t13-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHB (1 to 333) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441129
(CHEMBL2430741)Show SMILES C[C@@H](Nc1nc(cnc1N)-c1ccnc(c1)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C18H17N5O2/c1-11(12-5-3-2-4-6-12)22-17-16(19)21-10-15(23-17)13-7-8-20-14(9-13)18(24)25/h2-11H,1H3,(H2,19,21)(H,22,23)(H,24,25)/t11-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441110
(CHEMBL2430721)Show SMILES C[C@@H](Nc1cncc(n1)-c1cccc(c1)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C19H17N3O2/c1-13(14-6-3-2-4-7-14)21-18-12-20-11-17(22-18)15-8-5-9-16(10-15)19(23)24/h2-13H,1H3,(H,21,22)(H,23,24)/t13-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase B chain
(Homo sapiens (Human)) | BDBM50441116
(CHEMBL2430736)Show InChI InChI=1S/C18H16N4O2/c19-16-17(21-10-12-5-2-1-3-6-12)22-15(11-20-16)13-7-4-8-14(9-13)18(23)24/h1-9,11H,10H2,(H2,19,20)(H,21,22)(H,23,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHB (1 to 333) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441123
(CHEMBL2430729)Show SMILES C[C@@H](Nc1nc(cnc1N)-c1cccc(C(O)=O)c1C)c1ccccc1 |r| Show InChI InChI=1S/C20H20N4O2/c1-12-15(9-6-10-16(12)20(25)26)17-11-22-18(21)19(24-17)23-13(2)14-7-4-3-5-8-14/h3-11,13H,1-2H3,(H2,21,22)(H,23,24)(H,25,26)/t13-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase B chain
(Homo sapiens (Human)) | BDBM50441122
(CHEMBL2430730)Show SMILES C[C@@H](Nc1nc(cnc1N)-c1ccc(C)c(c1)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C20H20N4O2/c1-12-8-9-15(10-16(12)20(25)26)17-11-22-18(21)19(24-17)23-13(2)14-6-4-3-5-7-14/h3-11,13H,1-2H3,(H2,21,22)(H,23,24)(H,25,26)/t13-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHB (1 to 333) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase B chain
(Homo sapiens (Human)) | BDBM50441123
(CHEMBL2430729)Show SMILES C[C@@H](Nc1nc(cnc1N)-c1cccc(C(O)=O)c1C)c1ccccc1 |r| Show InChI InChI=1S/C20H20N4O2/c1-12-15(9-6-10-16(12)20(25)26)17-11-22-18(21)19(24-17)23-13(2)14-7-4-3-5-8-14/h3-11,13H,1-2H3,(H2,21,22)(H,23,24)(H,25,26)/t13-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHB (1 to 333) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase B chain
(Homo sapiens (Human)) | BDBM50441129
(CHEMBL2430741)Show SMILES C[C@@H](Nc1nc(cnc1N)-c1ccnc(c1)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C18H17N5O2/c1-11(12-5-3-2-4-6-12)22-17-16(19)21-10-15(23-17)13-7-8-20-14(9-13)18(24)25/h2-11H,1H3,(H2,19,21)(H,22,23)(H,24,25)/t11-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHB (1 to 333) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441124
(CHEMBL2430728)Show SMILES C[C@@H](Nc1nc(cnc1N)-c1csc(c1)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C17H16N4O2S/c1-10(11-5-3-2-4-6-11)20-16-15(18)19-8-13(21-16)12-7-14(17(22)23)24-9-12/h2-10H,1H3,(H2,18,19)(H,20,21)(H,22,23)/t10-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase B chain
(Homo sapiens (Human)) | BDBM50441111
(CHEMBL2430719)Show SMILES C[C@@H](Nc1cc(cnc1N)-c1cccc(c1)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C20H19N3O2/c1-13(14-6-3-2-4-7-14)23-18-11-17(12-22-19(18)21)15-8-5-9-16(10-15)20(24)25/h2-13,23H,1H3,(H2,21,22)(H,24,25)/t13-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHB (1 to 333) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441106
(CHEMBL2430725)Show SMILES C[C@@H](Nc1nc(cnc1NS(C)(=O)=O)-c1cccc(c1)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C20H20N4O4S/c1-13(14-7-4-3-5-8-14)22-19-18(24-29(2,27)28)21-12-17(23-19)15-9-6-10-16(11-15)20(25)26/h3-13H,1-2H3,(H,21,24)(H,22,23)(H,25,26)/t13-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 7.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441108
(CHEMBL2430723)Show SMILES CNc1ncc(nc1N[C@H](C)c1ccccc1)-c1cccc(c1)C(O)=O |r| Show InChI InChI=1S/C20H20N4O2/c1-13(14-7-4-3-5-8-14)23-19-18(21-2)22-12-17(24-19)15-9-6-10-16(11-15)20(25)26/h3-13H,1-2H3,(H,21,22)(H,23,24)(H,25,26)/t13-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase B chain
(Homo sapiens (Human)) | BDBM50441112
(CHEMBL2430717)Show InChI InChI=1S/C17H20N4O2/c18-15-16(20-9-11-4-1-2-5-11)21-14(10-19-15)12-6-3-7-13(8-12)17(22)23/h3,6-8,10-11H,1-2,4-5,9H2,(H2,18,19)(H,20,21)(H,22,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHB (1 to 333) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441105
(CHEMBL2430726)Show SMILES C[C@@H](Nc1nc(c(C)nc1N)-c1cccc(c1)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C20H20N4O2/c1-12(14-7-4-3-5-8-14)23-19-18(21)22-13(2)17(24-19)15-9-6-10-16(11-15)20(25)26/h3-12H,1-2H3,(H2,21,22)(H,23,24)(H,25,26)/t12-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase B chain
(Homo sapiens (Human)) | BDBM50441131
(CHEMBL2430739)Show SMILES C[C@@H](Nc1nc(cnc1N)-c1cccc(c1)C(N)=O)c1ccccc1 |r| Show InChI InChI=1S/C19H19N5O/c1-12(13-6-3-2-4-7-13)23-19-17(20)22-11-16(24-19)14-8-5-9-15(10-14)18(21)25/h2-12H,1H3,(H2,20,22)(H2,21,25)(H,23,24)/t12-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHB (1 to 333) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441128
(CHEMBL2430742)Show SMILES C[C@@H](Nc1nc(cnc1N)-c1ccccc1C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C19H18N4O2/c1-12(13-7-3-2-4-8-13)22-18-17(20)21-11-16(23-18)14-9-5-6-10-15(14)19(24)25/h2-12H,1H3,(H2,20,21)(H,22,23)(H,24,25)/t12-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase B chain
(Homo sapiens (Human)) | BDBM50441114
(CHEMBL2430715)Show SMILES C[C@@H](Oc1nc(cnc1N)-c1cccc(c1)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C19H17N3O3/c1-12(13-6-3-2-4-7-13)25-18-17(20)21-11-16(22-18)14-8-5-9-15(10-14)19(23)24/h2-12H,1H3,(H2,20,21)(H,23,24)/t12-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHB (1 to 333) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase B chain
(Homo sapiens (Human)) | BDBM50441109
(CHEMBL2430722)Show SMILES C[C@@H](Nc1nc(c[nH]c1=O)-c1cccc(c1)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C19H17N3O3/c1-12(13-6-3-2-4-7-13)21-17-18(23)20-11-16(22-17)14-8-5-9-15(10-14)19(24)25/h2-12H,1H3,(H,20,23)(H,21,22)(H,24,25)/t12-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHB (1 to 333) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441133
(CHEMBL2430720)Show SMILES C[C@@H](Nc1nc(ccc1N)-c1cccc(c1)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C20H19N3O2/c1-13(14-6-3-2-4-7-14)22-19-17(21)10-11-18(23-19)15-8-5-9-16(12-15)20(24)25/h2-13H,21H2,1H3,(H,22,23)(H,24,25)/t13-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase B chain
(Homo sapiens (Human)) | BDBM50441107
(CHEMBL2430724)Show SMILES C[C@@H](Nc1nc(cnc1NC(C)=O)-c1cccc(c1)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C21H20N4O3/c1-13(15-7-4-3-5-8-15)23-20-19(24-14(2)26)22-12-18(25-20)16-9-6-10-17(11-16)21(27)28/h3-13H,1-2H3,(H,23,25)(H,27,28)(H,22,24,26)/t13-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHB (1 to 333) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441109
(CHEMBL2430722)Show SMILES C[C@@H](Nc1nc(c[nH]c1=O)-c1cccc(c1)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C19H17N3O3/c1-12(13-6-3-2-4-7-13)21-17-18(23)20-11-16(22-17)14-8-5-9-15(10-14)19(24)25/h2-12H,1H3,(H,20,23)(H,21,22)(H,24,25)/t12-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase B chain
(Homo sapiens (Human)) | BDBM50441128
(CHEMBL2430742)Show SMILES C[C@@H](Nc1nc(cnc1N)-c1ccccc1C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C19H18N4O2/c1-12(13-7-3-2-4-8-13)22-18-17(20)21-11-16(23-18)14-9-5-6-10-15(14)19(24)25/h2-12H,1H3,(H2,20,21)(H,22,23)(H,24,25)/t12-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHB (1 to 333) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase B chain
(Homo sapiens (Human)) | BDBM50441105
(CHEMBL2430726)Show SMILES C[C@@H](Nc1nc(c(C)nc1N)-c1cccc(c1)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C20H20N4O2/c1-12(14-7-4-3-5-8-14)23-19-18(21)22-13(2)17(24-19)15-9-6-10-16(11-15)20(25)26/h3-12H,1-2H3,(H2,21,22)(H,23,24)(H,25,26)/t12-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHB (1 to 333) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441130
(CHEMBL2430740)Show SMILES C[C@@H](Nc1nc(cnc1N)-c1cccc(c1)C(=O)NS(C)(=O)=O)c1ccccc1 |r| Show InChI InChI=1S/C20H21N5O3S/c1-13(14-7-4-3-5-8-14)23-19-18(21)22-12-17(24-19)15-9-6-10-16(11-15)20(26)25-29(2,27)28/h3-13H,1-2H3,(H2,21,22)(H,23,24)(H,25,26)/t13-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441134
(CHEMBL2430718)Show InChI InChI=1S/C14H16N4O3/c1-21-6-5-16-13-12(15)17-8-11(18-13)9-3-2-4-10(7-9)14(19)20/h2-4,7-8H,5-6H2,1H3,(H2,15,17)(H,16,18)(H,19,20) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441107
(CHEMBL2430724)Show SMILES C[C@@H](Nc1nc(cnc1NC(C)=O)-c1cccc(c1)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C21H20N4O3/c1-13(15-7-4-3-5-8-15)23-20-19(24-14(2)26)22-12-18(25-20)16-9-6-10-17(11-16)21(27)28/h3-13H,1-2H3,(H,23,25)(H,27,28)(H,22,24,26)/t13-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase B chain
(Homo sapiens (Human)) | BDBM50441130
(CHEMBL2430740)Show SMILES C[C@@H](Nc1nc(cnc1N)-c1cccc(c1)C(=O)NS(C)(=O)=O)c1ccccc1 |r| Show InChI InChI=1S/C20H21N5O3S/c1-13(14-7-4-3-5-8-14)23-19-18(21)22-12-17(24-19)15-9-6-10-16(11-15)20(26)25-29(2,27)28/h3-13H,1-2H3,(H2,21,22)(H,23,24)(H,25,26)/t13-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHB (1 to 333) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441137
(CHEMBL2430738)Show SMILES CCOC(=O)c1cccc(c1)-c1cnc(N)c(N[C@H](C)c2ccccc2)n1 |r| Show InChI InChI=1S/C21H22N4O2/c1-3-27-21(26)17-11-7-10-16(12-17)18-13-23-19(22)20(25-18)24-14(2)15-8-5-4-6-9-15/h4-14H,3H2,1-2H3,(H2,22,23)(H,24,25)/t14-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441135
(CHEMBL2430714)Show SMILES C[C@@H](N(C)c1nc(cnc1N)-c1cccc(c1)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C20H20N4O2/c1-13(14-7-4-3-5-8-14)24(2)19-18(21)22-12-17(23-19)15-9-6-10-16(11-15)20(25)26/h3-13H,1-2H3,(H2,21,22)(H,25,26)/t13-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase B chain
(Homo sapiens (Human)) | BDBM50441124
(CHEMBL2430728)Show SMILES C[C@@H](Nc1nc(cnc1N)-c1csc(c1)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C17H16N4O2S/c1-10(11-5-3-2-4-6-11)20-16-15(18)19-8-13(21-16)12-7-14(17(22)23)24-9-12/h2-10H,1H3,(H2,18,19)(H,20,21)(H,22,23)/t10-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHB (1 to 333) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase B chain
(Homo sapiens (Human)) | BDBM50441106
(CHEMBL2430725)Show SMILES C[C@@H](Nc1nc(cnc1NS(C)(=O)=O)-c1cccc(c1)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C20H20N4O4S/c1-13(14-7-4-3-5-8-14)22-19-18(24-29(2,27)28)21-12-17(23-19)15-9-6-10-16(11-15)20(25)26/h3-13H,1-2H3,(H,21,24)(H,22,23)(H,25,26)/t13-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHB (1 to 333) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441136
(CHEMBL2430712)Show SMILES C[C@H](Nc1nc(cnc1N)-c1cccc(c1)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C19H18N4O2/c1-12(13-6-3-2-4-7-13)22-18-17(20)21-11-16(23-18)14-8-5-9-15(10-14)19(24)25/h2-12H,1H3,(H2,20,21)(H,22,23)(H,24,25)/t12-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase B chain
(Homo sapiens (Human)) | BDBM50441108
(CHEMBL2430723)Show SMILES CNc1ncc(nc1N[C@H](C)c1ccccc1)-c1cccc(c1)C(O)=O |r| Show InChI InChI=1S/C20H20N4O2/c1-13(14-7-4-3-5-8-14)23-19-18(21-2)22-12-17(24-19)15-9-6-10-16(11-15)20(25)26/h3-13H,1-2H3,(H,21,22)(H,23,24)(H,25,26)/t13-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHB (1 to 333) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441131
(CHEMBL2430739)Show SMILES C[C@@H](Nc1nc(cnc1N)-c1cccc(c1)C(N)=O)c1ccccc1 |r| Show InChI InChI=1S/C19H19N5O/c1-12(13-6-3-2-4-7-13)23-19-17(20)22-11-16(24-19)14-8-5-9-15(10-14)18(21)25/h2-12H,1H3,(H2,20,22)(H2,21,25)(H,23,24)/t12-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441114
(CHEMBL2430715)Show SMILES C[C@@H](Oc1nc(cnc1N)-c1cccc(c1)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C19H17N3O3/c1-12(13-6-3-2-4-7-13)25-18-17(20)21-11-16(22-18)14-8-5-9-15(10-14)19(23)24/h2-12H,1H3,(H2,20,21)(H,23,24)/t12-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441117
(CHEMBL2430735)Show SMILES C[C@@H](Nc1nc(cnc1N)-c1cc(ccc1Cl)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C19H17ClN4O2/c1-11(12-5-3-2-4-6-12)23-18-17(21)22-10-16(24-18)14-9-13(19(25)26)7-8-15(14)20/h2-11H,1H3,(H2,21,22)(H,23,24)(H,25,26)/t11-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem
Similars
| PDB
Article
PubMed
| n/a | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Binding affinity to human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli by surface plasmon resonance analysis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441121
(CHEMBL2430731)Show SMILES C[C@@H](Nc1nc(cnc1N)-c1cc(C)cc(c1)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C20H20N4O2/c1-12-8-15(10-16(9-12)20(25)26)17-11-22-18(21)19(24-17)23-13(2)14-6-4-3-5-7-14/h3-11,13H,1-2H3,(H2,21,22)(H,23,24)(H,25,26)/t13-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Binding affinity to human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli by surface plasmon resonance analysis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441112
(CHEMBL2430717)Show InChI InChI=1S/C17H20N4O2/c18-15-16(20-9-11-4-1-2-5-11)21-14(10-19-15)12-6-3-7-13(8-12)17(22)23/h3,6-8,10-11H,1-2,4-5,9H2,(H2,18,19)(H,20,21)(H,22,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 1.80E+4 | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Binding affinity to human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli by surface plasmon resonance analysis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441132
(CHEMBL2430737)Show SMILES C[C@@H](Nc1nc(cnc1N)-c1cccc(c1)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C19H18N4O2/c1-12(13-6-3-2-4-7-13)22-18-17(20)21-11-16(23-18)14-8-5-9-15(10-14)19(24)25/h2-12H,1H3,(H2,20,21)(H,22,23)(H,24,25)/t12-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 8.57E+5 | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Binding affinity to human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli by surface plasmon resonance analysis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441108
(CHEMBL2430723)Show SMILES CNc1ncc(nc1N[C@H](C)c1ccccc1)-c1cccc(c1)C(O)=O |r| Show InChI InChI=1S/C20H20N4O2/c1-13(14-7-4-3-5-8-14)23-19-18(21-2)22-12-17(24-19)15-9-6-10-16(11-15)20(25)26/h3-13H,1-2H3,(H,21,22)(H,23,24)(H,25,26)/t13-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Binding affinity to human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli by surface plasmon resonance analysis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441109
(CHEMBL2430722)Show SMILES C[C@@H](Nc1nc(c[nH]c1=O)-c1cccc(c1)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C19H17N3O3/c1-12(13-6-3-2-4-7-13)21-17-18(23)20-11-16(22-17)14-8-5-9-15(10-14)19(24)25/h2-12H,1H3,(H,20,23)(H,21,22)(H,24,25)/t12-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Binding affinity to human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli by surface plasmon resonance analysis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441110
(CHEMBL2430721)Show SMILES C[C@@H](Nc1cncc(n1)-c1cccc(c1)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C19H17N3O2/c1-13(14-6-3-2-4-7-14)21-18-12-20-11-17(22-18)15-8-5-9-16(10-15)19(23)24/h2-13H,1H3,(H,21,22)(H,23,24)/t13-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Binding affinity to human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli by surface plasmon resonance analysis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441135
(CHEMBL2430714)Show SMILES C[C@@H](N(C)c1nc(cnc1N)-c1cccc(c1)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C20H20N4O2/c1-13(14-7-4-3-5-8-14)24(2)19-18(21)22-12-17(23-19)15-9-6-10-16(11-15)20(25)26/h3-13H,1-2H3,(H2,21,22)(H,25,26)/t13-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Binding affinity to human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli by surface plasmon resonance analysis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441116
(CHEMBL2430736)Show InChI InChI=1S/C18H16N4O2/c19-16-17(21-10-12-5-2-1-3-6-12)22-15(11-20-16)13-7-4-8-14(9-13)18(23)24/h1-9,11H,10H2,(H2,19,20)(H,21,22)(H,23,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 2.20E+4 | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Binding affinity to human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli by surface plasmon resonance analysis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441131
(CHEMBL2430739)Show SMILES C[C@@H](Nc1nc(cnc1N)-c1cccc(c1)C(N)=O)c1ccccc1 |r| Show InChI InChI=1S/C19H19N5O/c1-12(13-6-3-2-4-7-13)23-19-17(20)22-11-16(24-19)14-8-5-9-15(10-14)18(21)25/h2-12H,1H3,(H2,20,22)(H2,21,25)(H,23,24)/t12-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Binding affinity to human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli by surface plasmon resonance analysis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441132
(CHEMBL2430737)Show SMILES C[C@@H](Nc1nc(cnc1N)-c1cccc(c1)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C19H18N4O2/c1-12(13-6-3-2-4-7-13)22-18-17(20)21-11-16(23-18)14-8-5-9-15(10-14)19(24)25/h2-12H,1H3,(H2,20,21)(H,22,23)(H,24,25)/t12-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Binding affinity to human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli by surface plasmon resonance analysis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441111
(CHEMBL2430719)Show SMILES C[C@@H](Nc1cc(cnc1N)-c1cccc(c1)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C20H19N3O2/c1-13(14-6-3-2-4-7-14)23-18-11-17(12-22-19(18)21)15-8-5-9-16(10-15)20(24)25/h2-13,23H,1H3,(H2,21,22)(H,24,25)/t13-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 2.90E+4 | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Binding affinity to human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli by surface plasmon resonance analysis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441134
(CHEMBL2430718)Show InChI InChI=1S/C14H16N4O3/c1-21-6-5-16-13-12(15)17-8-11(18-13)9-3-2-4-10(7-9)14(19)20/h2-4,7-8H,5-6H2,1H3,(H2,15,17)(H,16,18)(H,19,20) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Binding affinity to human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli by surface plasmon resonance analysis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441120
(CHEMBL2430732)Show SMILES C[C@@H](Nc1nc(cnc1N)-c1cc(ccc1C)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C20H20N4O2/c1-12-8-9-15(20(25)26)10-16(12)17-11-22-18(21)19(24-17)23-13(2)14-6-4-3-5-7-14/h3-11,13H,1-2H3,(H2,21,22)(H,23,24)(H,25,26)/t13-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Binding affinity to human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli by surface plasmon resonance analysis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441124
(CHEMBL2430728)Show SMILES C[C@@H](Nc1nc(cnc1N)-c1csc(c1)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C17H16N4O2S/c1-10(11-5-3-2-4-6-11)20-16-15(18)19-8-13(21-16)12-7-14(17(22)23)24-9-12/h2-10H,1H3,(H2,18,19)(H,20,21)(H,22,23)/t10-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 3.30E+4 | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Binding affinity to human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli by surface plasmon resonance analysis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441128
(CHEMBL2430742)Show SMILES C[C@@H](Nc1nc(cnc1N)-c1ccccc1C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C19H18N4O2/c1-12(13-7-3-2-4-8-13)22-18-17(20)21-11-16(23-18)14-9-5-6-10-15(14)19(24)25/h2-12H,1H3,(H2,20,21)(H,22,23)(H,24,25)/t12-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Binding affinity to human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli by surface plasmon resonance analysis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441129
(CHEMBL2430741)Show SMILES C[C@@H](Nc1nc(cnc1N)-c1ccnc(c1)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C18H17N5O2/c1-11(12-5-3-2-4-6-12)22-17-16(19)21-10-15(23-17)13-7-8-20-14(9-13)18(24)25/h2-11H,1H3,(H2,19,21)(H,22,23)(H,24,25)/t11-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 3.20E+4 | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Binding affinity to human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli by surface plasmon resonance analysis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441137
(CHEMBL2430738)Show SMILES CCOC(=O)c1cccc(c1)-c1cnc(N)c(N[C@H](C)c2ccccc2)n1 |r| Show InChI InChI=1S/C21H22N4O2/c1-3-27-21(26)17-11-7-10-16(12-17)18-13-23-19(22)20(25-18)24-14(2)15-8-5-4-6-9-15/h4-14H,3H2,1-2H3,(H2,22,23)(H,24,25)/t14-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Binding affinity to human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli by surface plasmon resonance analysis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441118
(CHEMBL2430734)Show SMILES COc1ccc(cc1-c1cnc(N)c(N[C@H](C)c2ccccc2)n1)C(O)=O |r| Show InChI InChI=1S/C20H20N4O3/c1-12(13-6-4-3-5-7-13)23-19-18(21)22-11-16(24-19)15-10-14(20(25)26)8-9-17(15)27-2/h3-12H,1-2H3,(H2,21,22)(H,23,24)(H,25,26)/t12-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Binding affinity to human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli by surface plasmon resonance analysis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441105
(CHEMBL2430726)Show SMILES C[C@@H](Nc1nc(c(C)nc1N)-c1cccc(c1)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C20H20N4O2/c1-12(14-7-4-3-5-8-14)23-19-18(21)22-13(2)17(24-19)15-9-6-10-16(11-15)20(25)26/h3-12H,1-2H3,(H2,21,22)(H,23,24)(H,25,26)/t12-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Binding affinity to human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli by surface plasmon resonance analysis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441136
(CHEMBL2430712)Show SMILES C[C@H](Nc1nc(cnc1N)-c1cccc(c1)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C19H18N4O2/c1-12(13-6-3-2-4-7-13)22-18-17(20)21-11-16(23-18)14-8-5-9-15(10-14)19(24)25/h2-12H,1H3,(H2,20,21)(H,22,23)(H,24,25)/t12-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Binding affinity to human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli by surface plasmon resonance analysis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441119
(CHEMBL2430733)Show SMILES CC(C)c1ccc(cc1-c1cnc(N)c(N[C@H](C)c2ccccc2)n1)C(O)=O |r| Show InChI InChI=1S/C22H24N4O2/c1-13(2)17-10-9-16(22(27)28)11-18(17)19-12-24-20(23)21(26-19)25-14(3)15-7-5-4-6-8-15/h4-14H,1-3H3,(H2,23,24)(H,25,26)(H,27,28)/t14-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Binding affinity to human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli by surface plasmon resonance analysis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441122
(CHEMBL2430730)Show SMILES C[C@@H](Nc1nc(cnc1N)-c1ccc(C)c(c1)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C20H20N4O2/c1-12-8-9-15(10-16(12)20(25)26)17-11-22-18(21)19(24-17)23-13(2)14-6-4-3-5-7-14/h3-11,13H,1-2H3,(H2,21,22)(H,23,24)(H,25,26)/t13-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 2.90E+4 | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Binding affinity to human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli by surface plasmon resonance analysis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441123
(CHEMBL2430729)Show SMILES C[C@@H](Nc1nc(cnc1N)-c1cccc(C(O)=O)c1C)c1ccccc1 |r| Show InChI InChI=1S/C20H20N4O2/c1-12-15(9-6-10-16(12)20(25)26)17-11-22-18(21)19(24-17)23-13(2)14-7-4-3-5-8-14/h3-11,13H,1-2H3,(H2,21,22)(H,23,24)(H,25,26)/t13-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Binding affinity to human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli by surface plasmon resonance analysis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441133
(CHEMBL2430720)Show SMILES C[C@@H](Nc1nc(ccc1N)-c1cccc(c1)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C20H19N3O2/c1-13(14-6-3-2-4-7-14)22-19-17(21)10-11-18(23-19)15-8-5-9-16(12-15)20(24)25/h2-13H,21H2,1H3,(H,22,23)(H,24,25)/t13-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Binding affinity to human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli by surface plasmon resonance analysis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441113
(CHEMBL2430716)Show SMILES C[C@@H](Nc1nc(cnc1N)-c1cccc(c1)C(O)=O)C1CCCCC1 |r| Show InChI InChI=1S/C19H24N4O2/c1-12(13-6-3-2-4-7-13)22-18-17(20)21-11-16(23-18)14-8-5-9-15(10-14)19(24)25/h5,8-13H,2-4,6-7H2,1H3,(H2,20,21)(H,22,23)(H,24,25)/t12-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Binding affinity to human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli by surface plasmon resonance analysis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441114
(CHEMBL2430715)Show SMILES C[C@@H](Oc1nc(cnc1N)-c1cccc(c1)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C19H17N3O3/c1-12(13-6-3-2-4-7-13)25-18-17(20)21-11-16(22-18)14-8-5-9-15(10-14)19(23)24/h2-12H,1H3,(H2,20,21)(H,23,24)/t12-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Binding affinity to human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli by surface plasmon resonance analysis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441115
(CHEMBL2430713)Show SMILES C[C@@H](Nc1nc(cnc1N)-c1cccc(c1)C(O)=O)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C19H17ClN4O2/c1-11(12-5-7-15(20)8-6-12)23-18-17(21)22-10-16(24-18)13-3-2-4-14(9-13)19(25)26/h2-11H,1H3,(H2,21,22)(H,23,24)(H,25,26)/t11-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Binding affinity to human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli by surface plasmon resonance analysis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
L-lactate dehydrogenase A chain
(Homo sapiens (Human)) | BDBM50441130
(CHEMBL2430740)Show SMILES C[C@@H](Nc1nc(cnc1N)-c1cccc(c1)C(=O)NS(C)(=O)=O)c1ccccc1 |r| Show InChI InChI=1S/C20H21N5O3S/c1-13(14-7-4-3-5-8-14)23-19-18(21)22-12-17(24-19)15-9-6-10-16(11-15)20(26)25-29(2,27)28/h3-13H,1-2H3,(H2,21,22)(H,23,24)(H,25,26)/t13-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description
Binding affinity to human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli by surface plasmon resonance analysis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060
BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this
Ligand-Target Pair | |
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